Nadzan AM - Search Results

1

Discovery of potent and orally available malonyl-CoA decarboxylase inhibitors as cardioprotective agents.

Cheng JF, Huang Y, Penuliar R, Nishimoto M, Liu L, Arrhenius T, Yang G, O'leary E, Barbosa M, Barr R, Dyck JR, Lopaschuk GD, Nadzan AM. Cheng JF, et al. Among authors: nadzan am. J Med Chem. 2006 Jul 13;49(14):4055-8. doi: 10.1021/jm0605029. J Med Chem. 2006. PMID: 16821767

2

Novel chromene derivatives as TNF-alpha inhibitors.

Cheng JF, Ishikawa A, Ono Y, Arrhenius T, Nadzan A. Cheng JF, et al. Bioorg Med Chem Lett. 2003 Nov 3;13(21):3647-50. doi: 10.1016/j.bmcl.2003.08.025. Bioorg Med Chem Lett. 2003. PMID: 14552749

3

Discovery and structure-activity relationship of coumarin derivatives as TNF-alpha inhibitors.

Cheng JF, Chen M, Wallace D, Tith S, Arrhenius T, Kashiwagi H, Ono Y, Ishikawa A, Sato H, Kozono T, Sato H, Nadzan AM. Cheng JF, et al. Among authors: nadzan am. Bioorg Med Chem Lett. 2004 May 17;14(10):2411-5. doi: 10.1016/j.bmcl.2004.03.022. Bioorg Med Chem Lett. 2004. PMID: 15109623

4

Design and synthesis of heterocyclic malonyl-CoA decarboxylase inhibitors.

Cheng JF, Chen M, Liu B, Hou Z, Arrhenius T, Nadzan AM. Cheng JF, et al. Among authors: nadzan am. Bioorg Med Chem Lett. 2006 Feb;16(3):695-700. doi: 10.1016/j.bmcl.2005.10.020. Epub 2005 Oct 27. Bioorg Med Chem Lett. 2006. PMID: 16257202

5

Synthesis and structure-activity relationship of small-molecule malonyl coenzyme A decarboxylase inhibitors.

Cheng JF, Chen M, Wallace D, Tith S, Haramura M, Liu B, Mak CC, Arrhenius T, Reily S, Brown S, Thorn V, Harmon C, Barr R, Dyck JR, Lopaschuk GD, Nadzan AM. Cheng JF, et al. Among authors: nadzan am. J Med Chem. 2006 Mar 9;49(5):1517-25. doi: 10.1021/jm050109n. J Med Chem. 2006. PMID: 16509570

6

Heteroaryl substituted bis-trifluoromethyl carbinols as malonyl-CoA decarboxylase inhibitors.

Cheng JF, Mak CC, Huang Y, Penuliar R, Nishimoto M, Zhang L, Chen M, Wallace D, Arrhenius T, Chu D, Yang G, Barbosa M, Barr R, Dyck JR, Lopaschuk GD, Nadzan AM. Cheng JF, et al. Among authors: nadzan am. Bioorg Med Chem Lett. 2006 Jul 1;16(13):3484-8. doi: 10.1016/j.bmcl.2006.03.100. Epub 2006 Apr 27. Bioorg Med Chem Lett. 2006. PMID: 16644218

7

Novel trifluoroacetophenone derivatives as malonyl-CoA decarboxylase inhibitors.

Wallace DM, Haramura M, Cheng JF, Arrhenius T, Nadzan AM. Wallace DM, et al. Among authors: nadzan am. Bioorg Med Chem Lett. 2007 Feb 15;17(4):1127-30. doi: 10.1016/j.bmcl.2006.09.023. Epub 2007 Jan 17. Bioorg Med Chem Lett. 2007. PMID: 17234415

8

Expression, purification, and characterization of human malonyl-CoA decarboxylase.

Zhou D, Yuen P, Chu D, Thon V, McConnell S, Brown S, Tsang A, Pena M, Russell A, Cheng JF, Nadzan AM, Barbosa MS, Dyck JR, Lopaschuk GD, Yang G. Zhou D, et al. Among authors: nadzan am. Protein Expr Purif. 2004 Apr;34(2):261-9. doi: 10.1016/j.pep.2003.11.023. Protein Expr Purif. 2004. PMID: 15003260

9

Malonyl coenzyme a decarboxylase inhibition protects the ischemic heart by inhibiting fatty acid oxidation and stimulating glucose oxidation.

Dyck JR, Cheng JF, Stanley WC, Barr R, Chandler MP, Brown S, Wallace D, Arrhenius T, Harmon C, Yang G, Nadzan AM, Lopaschuk GD. Dyck JR, et al. Among authors: nadzan am. Circ Res. 2004 May 14;94(9):e78-84. doi: 10.1161/01.RES.0000129255.19569.8f. Epub 2004 Apr 22. Circ Res. 2004. PMID: 15105298

10

Analysis of combinatorial chemistry samples by micellar electrokinetic chromatography.

Simms PJ, Jeffries CT, Huang Y, Zhang L, Arrhenius T, Nadzan AM. Simms PJ, et al. Among authors: nadzan am. J Comb Chem. 2001 Sep-Oct;3(5):427-33. doi: 10.1021/cc000093g. J Comb Chem. 2001. PMID: 11549360

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