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Dissociation of pathological and molecular phenotype of variant Creutzfeldt-Jakob disease in transgenic human prion protein 129 heterozygous mice.
Asante EA, Linehan JM, Gowland I, Joiner S, Fox K, Cooper S, Osiguwa O, Gorry M, Welch J, Houghton R, Desbruslais M, Brandner S, Wadsworth JD, Collinge J. Asante EA, et al. Among authors: gowland i. Proc Natl Acad Sci U S A. 2006 Jul 11;103(28):10759-64. doi: 10.1073/pnas.0604292103. Epub 2006 Jun 29. Proc Natl Acad Sci U S A. 2006. PMID: 16809423 Free PMC article.
Human prion protein with valine 129 prevents expression of variant CJD phenotype.
Wadsworth JD, Asante EA, Desbruslais M, Linehan JM, Joiner S, Gowland I, Welch J, Stone L, Lloyd SE, Hill AF, Brandner S, Collinge J. Wadsworth JD, et al. Among authors: gowland i. Science. 2004 Dec 3;306(5702):1793-6. doi: 10.1126/science.1103932. Epub 2004 Nov 11. Science. 2004. PMID: 15539564
The same prion strain causes vCJD and BSE.
Hill AF, Desbruslais M, Joiner S, Sidle KC, Gowland I, Collinge J, Doey LJ, Lantos P. Hill AF, et al. Among authors: gowland i. Nature. 1997 Oct 2;389(6650):448-50, 526. doi: 10.1038/38925. Nature. 1997. PMID: 9333232 No abstract available.
12 results