Lees AJ - Search Results

1

Altered cleavage and localization of PINK1 to aggresomes in the presence of proteasomal stress.

Muqit MM, Abou-Sleiman PM, Saurin AT, Harvey K, Gandhi S, Deas E, Eaton S, Payne Smith MD, Venner K, Matilla A, Healy DG, Gilks WP, Lees AJ, Holton J, Revesz T, Parker PJ, Harvey RJ, Wood NW, Latchman DS. Muqit MM, et al. Among authors: lees aj. J Neurochem. 2006 Jul;98(1):156-69. doi: 10.1111/j.1471-4159.2006.03845.x. J Neurochem. 2006. PMID: 16805805 Free article.

2

The gene responsible for PARK6 Parkinson's disease, PINK1, does not influence common forms of parkinsonism.

Healy DG, Abou-Sleiman PM, Ahmadi KR, Muqit MM, Bhatia KP, Quinn NP, Lees AJ, Latchmann DS, Goldstein DB, Wood NW. Healy DG, et al. Among authors: lees aj. Ann Neurol. 2004 Sep;56(3):329-35. doi: 10.1002/ana.20206. Ann Neurol. 2004. PMID: 15349859

3

Synphilin-1 and parkin show overlapping expression patterns in human brain and form aggresomes in response to proteasomal inhibition.

Bandopadhyay R, Kingsbury AE, Muqit MM, Harvey K, Reid AR, Kilford L, Engelender S, Schlossmacher MG, Wood NW, Latchman DS, Harvey RJ, Lees AJ. Bandopadhyay R, et al. Among authors: lees aj. Neurobiol Dis. 2005 Nov;20(2):401-11. doi: 10.1016/j.nbd.2005.03.021. Neurobiol Dis. 2005. PMID: 15894486

4

PINK1 protein in normal human brain and Parkinson's disease.

Gandhi S, Muqit MM, Stanyer L, Healy DG, Abou-Sleiman PM, Hargreaves I, Heales S, Ganguly M, Parsons L, Lees AJ, Latchman DS, Holton JL, Wood NW, Revesz T. Gandhi S, et al. Among authors: lees aj. Brain. 2006 Jul;129(Pt 7):1720-31. doi: 10.1093/brain/awl114. Epub 2006 May 15. Brain. 2006. PMID: 16702191

5

TDP-43 pathology is present in most post-encephalitic parkinsonism brains.

Ling H, Holton JL, Lees AJ, Revesz T. Ling H, et al. Among authors: lees aj. Neuropathol Appl Neurobiol. 2014 Aug;40(5):654-7. doi: 10.1111/nan.12067. Neuropathol Appl Neurobiol. 2014. PMID: 23763789 No abstract available.

6

A common LRRK2 mutation in idiopathic Parkinson's disease.

Gilks WP, Abou-Sleiman PM, Gandhi S, Jain S, Singleton A, Lees AJ, Shaw K, Bhatia KP, Bonifati V, Quinn NP, Lynch J, Healy DG, Holton JL, Revesz T, Wood NW. Gilks WP, et al. Among authors: lees aj. Lancet. 2005 Jan 29-Feb 4;365(9457):415-6. doi: 10.1016/S0140-6736(05)17830-1. Lancet. 2005. PMID: 15680457

7

UCHL-1 is not a Parkinson's disease susceptibility gene.

Healy DG, Abou-Sleiman PM, Casas JP, Ahmadi KR, Lynch T, Gandhi S, Muqit MM, Foltynie T, Barker R, Bhatia KP, Quinn NP, Lees AJ, Gibson JM, Holton JL, Revesz T, Goldstein DB, Wood NW. Healy DG, et al. Among authors: lees aj. Ann Neurol. 2006 Apr;59(4):627-33. doi: 10.1002/ana.20757. Ann Neurol. 2006. PMID: 16450370

8

NR4A2 genetic variation in sporadic Parkinson's disease: a genewide approach.

Healy DG, Abou-Sleiman PM, Ahmadi KR, Gandhi S, Muqit MM, Bhatia KP, Quinn NP, Lees AJ, Holton JL, Revesz T, Wood NW. Healy DG, et al. Among authors: lees aj. Mov Disord. 2006 Nov;21(11):1960-3. doi: 10.1002/mds.21018. Mov Disord. 2006. PMID: 16977628

9

Glucocerebrosidase mutations do not cause increased Lewy body pathology in Parkinson's disease.

Parkkinen L, Neumann J, O'Sullivan SS, Holton JL, Revesz T, Hardy J, Lees AJ. Parkkinen L, et al. Among authors: lees aj. Mol Genet Metab. 2011 Aug;103(4):410-2. doi: 10.1016/j.ymgme.2011.04.015. Epub 2011 May 5. Mol Genet Metab. 2011. PMID: 21621439

10

The role of pathogenic DJ-1 mutations in Parkinson's disease.

Abou-Sleiman PM, Healy DG, Quinn N, Lees AJ, Wood NW. Abou-Sleiman PM, et al. Among authors: lees aj. Ann Neurol. 2003 Sep;54(3):283-6. doi: 10.1002/ana.10675. Ann Neurol. 2003. PMID: 12953260

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