Ghelardini C - Search Results

1

Enantioselective synthesis and preliminary pharmacological evaluation of the enantiomers of unifiram (DM232), a potent cognition-enhancing agent.

Martini E, Ghelardini C, Bertucci C, Dei S, Gualtieri F, Guandalini L, Manetti D, Scapecchi S, Teodori E, Romanelli MN. Martini E, et al. Among authors: ghelardini c. Med Chem. 2005 Sep;1(5):473-80. doi: 10.2174/1573406054864142. Med Chem. 2005. PMID: 16787332

2

Analgesic, antimuscarinic activity and enantioselectivity of the four isomers of 3-quinuclidinyl tropate as compared with the enantiomers of hyoscyamine.

Dei S, Bellucci C, Gualtieri F, Romanelli MN, Scapecchi S, Teodori E, Bartolini A, Ghelardini C. Dei S, et al. Among authors: ghelardini c. Farmaco. 1995 May;50(5):303-9. Farmaco. 1995. PMID: 7626164

3

Presynaptic cholinergic modulators as potent cognition enhancers and analgesic drugs. 1. Tropic and 2-phenylpropionic acid esters.

Gualtieri F, Conti G, Dei S, Giovannoni MP, Nannucci F, Romanelli MN, Scapecchi S, Teodori E, Fanfani L, Ghelardini C, et al. Gualtieri F, et al. Among authors: ghelardini c. J Med Chem. 1994 May 27;37(11):1704-11. doi: 10.1021/jm00037a022. J Med Chem. 1994. PMID: 8201605

4

Synthesis and biological activity of a series of aryl tropanyl esters and amides chemically related to 1H-indole-3-carboxylic acid endo 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester. Development of a 5-HT4 agonist endowed with potent antinociceptive activity.

Romanelli MN, Ghelardini C, Dei S, Matucci R, Mori F, Scapecchi S, Teodori E, Bartolini A, Galli A, Giotti A, et al. Romanelli MN, et al. Among authors: ghelardini c. Arzneimittelforschung. 1993 Aug;43(8):913-8. Arzneimittelforschung. 1993. PMID: 8216452

5

Synthesis, characterization and pharmacological profile of tropicamide enantiomers.

Dei S, Bellucci C, Ghelardini C, Romanelli MN, Spampinato S. Dei S, et al. Among authors: ghelardini c. Life Sci. 1996;58(23):2147-53. doi: 10.1016/0024-3205(96)00208-1. Life Sci. 1996. PMID: 8649199

6

Synthesis and enantioselectivity of the enantiomers of PG9 and SM21, new potent analgesic and cognition-enhancing drugs.

Romanelli MN, Bartolini A, Bertucci C, Dei S, Ghelardini C, Giovannini MG, Gualtieri F, Pepeu G, Scapecchi S, Teodori E. Romanelli MN, et al. Among authors: ghelardini c. Chirality. 1996;8(3):225-33. doi: 10.1002/(SICI)1520-636X(1996)8:3<225::AID-CHIR1>3.0.CO;2-G. Chirality. 1996. PMID: 8777145

7

S-(-)-ET 126: a potent and selective M1 antagonist in vitro and in vivo.

Ghelardini C, Bartolini A, Galeotti N, Teodori E, Gualtieri F. Ghelardini C, et al. Life Sci. 1996;58(12):991-1000. doi: 10.1016/0024-3205(96)00047-1. Life Sci. 1996. PMID: 8786711

8

Reduced flexibility analogs of analgesic and cognition enhancing alpha-tropanyl esters.

Manetti D, Romanelli MN, Bartolini A, Dei S, Ghelardini C, Gualtieri F, Matucci R, Scapecchi S, Teodori E. Manetti D, et al. Among authors: ghelardini c. Arch Pharm (Weinheim). 1996 Feb;329(2):105-11. doi: 10.1002/ardp.19963290208. Arch Pharm (Weinheim). 1996. PMID: 8851474

9

Chiral synthesis and pharmacological evaluation of the enantiomers of SM32, a new analgesic and cognition-enhancing agent.

Romanelli MN, Bartolini A, Bertucci C, Dei S, Ghelardini C, Giovannini MG, Gualtieri F, Pepeu G, Scapecchi S, Teodori E. Romanelli MN, et al. Among authors: ghelardini c. Chirality. 1996;8(8):579-84. doi: 10.1002/(SICI)1520-636X(1996)8:8<579::AID-CHIR7>3.0.CO;2-4. Chirality. 1996. PMID: 9025257

10

Stereoselective increase in cholinergic transmission by R-(+)-hyoscyamine.

Ghelardini C, Gualtieri F, Novella Romanelli M, Angeli P, Pepeu G, Grazia Giovannini M, Casamenti F, Malmberg-Aiello P, Giotti A, Bartolini A. Ghelardini C, et al. Neuropharmacology. 1997 Mar;36(3):281-94. doi: 10.1016/s0028-3908(97)83761-6. Neuropharmacology. 1997. PMID: 9175606

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