Gottesman MM - Search Results

1

Melanosomal sequestration of cytotoxic drugs contributes to the intractability of malignant melanomas.

Chen KG, Valencia JC, Lai B, Zhang G, Paterson JK, Rouzaud F, Berens W, Wincovitch SM, Garfield SH, Leapman RD, Hearing VJ, Gottesman MM. Chen KG, et al. Among authors: gottesman mm. Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):9903-7. doi: 10.1073/pnas.0600213103. Epub 2006 Jun 15. Proc Natl Acad Sci U S A. 2006. PMID: 16777967 Free PMC article.

2

Transgenic mice that express the human multidrug-resistance gene in bone marrow enable a rapid identification of agents that reverse drug resistance.

Mickisch GH, Merlino GT, Galski H, Gottesman MM, Pastan I. Mickisch GH, et al. Among authors: gottesman mm. Proc Natl Acad Sci U S A. 1991 Jan 15;88(2):547-51. doi: 10.1073/pnas.88.2.547. Proc Natl Acad Sci U S A. 1991. PMID: 1671173 Free PMC article.

3

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues.

Thiebaut F, Tsuruo T, Hamada H, Gottesman MM, Pastan I, Willingham MC. Thiebaut F, et al. Among authors: gottesman mm. Proc Natl Acad Sci U S A. 1987 Nov;84(21):7735-8. doi: 10.1073/pnas.84.21.7735. Proc Natl Acad Sci U S A. 1987. PMID: 2444983 Free PMC article.

4

A retrovirus carrying an MDR1 cDNA confers multidrug resistance and polarized expression of P-glycoprotein in MDCK cells.

Pastan I, Gottesman MM, Ueda K, Lovelace E, Rutherford AV, Willingham MC. Pastan I, et al. Among authors: gottesman mm. Proc Natl Acad Sci U S A. 1988 Jun;85(12):4486-90. doi: 10.1073/pnas.85.12.4486. Proc Natl Acad Sci U S A. 1988. PMID: 2898143 Free PMC article.

5

ATP-dependent transport of vinblastine in vesicles from human multidrug-resistant cells.

Horio M, Gottesman MM, Pastan I. Horio M, et al. Among authors: gottesman mm. Proc Natl Acad Sci U S A. 1988 May;85(10):3580-4. doi: 10.1073/pnas.85.10.3580. Proc Natl Acad Sci U S A. 1988. PMID: 3368466 Free PMC article.

6

Drug-selected coexpression of human glucocerebrosidase and P-glycoprotein using a bicistronic vector.

Aran JM, Gottesman MM, Pastan I. Aran JM, et al. Among authors: gottesman mm. Proc Natl Acad Sci U S A. 1994 Apr 12;91(8):3176-80. doi: 10.1073/pnas.91.8.3176. Proc Natl Acad Sci U S A. 1994. PMID: 7909160 Free PMC article.

7

A human mitochondrial ATP-dependent protease that is highly homologous to bacterial Lon protease.

Wang N, Gottesman S, Willingham MC, Gottesman MM, Maurizi MR. Wang N, et al. Among authors: gottesman s, gottesman mm. Proc Natl Acad Sci U S A. 1993 Dec 1;90(23):11247-51. doi: 10.1073/pnas.90.23.11247. Proc Natl Acad Sci U S A. 1993. PMID: 8248235 Free PMC article.

8

Evidence for two nonidentical drug-interaction sites in the human P-glycoprotein.

Dey S, Ramachandra M, Pastan I, Gottesman MM, Ambudkar SV. Dey S, et al. Among authors: gottesman mm. Proc Natl Acad Sci U S A. 1997 Sep 30;94(20):10594-9. doi: 10.1073/pnas.94.20.10594. Proc Natl Acad Sci U S A. 1997. PMID: 9380680 Free PMC article.

9

Drug selection with paclitaxel restores expression of linked IL-2 receptor gamma -chain and multidrug resistance (MDR1) transgenes in canine bone marrow.

Licht T, Haskins M, Henthorn P, Kleiman SE, Bodine DM, Whitwam T, Puck JM, Gottesman MM, Melniczek JR. Licht T, et al. Among authors: gottesman mm. Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):3123-8. doi: 10.1073/pnas.052712199. Epub 2002 Feb 26. Proc Natl Acad Sci U S A. 2002. PMID: 11867757 Free PMC article.

10

Topical colchicine selection of keratinocytes transduced with the multidrug resistance gene (MDR1) can sustain and enhance transgene expression in vivo.

Pfutzner W, Terunuma A, Tock CL, Snead EK, Kolodka TM, Gottesman MM, Taichman L, Vogel JC. Pfutzner W, et al. Among authors: gottesman mm. Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):13096-101. doi: 10.1073/pnas.192247899. Epub 2002 Sep 16. Proc Natl Acad Sci U S A. 2002. PMID: 12235361 Free PMC article.

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