Curran T - Search Results

1

The hedgehog pathway and neurological disorders.

Dellovade T, Romer JT, Curran T, Rubin LL. Dellovade T, et al. Among authors: curran t. Annu Rev Neurosci. 2006;29:539-63. doi: 10.1146/annurev.neuro.29.051605.112858. Annu Rev Neurosci. 2006. PMID: 16776596 Review.

2

Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice.

Romer JT, Kimura H, Magdaleno S, Sasai K, Fuller C, Baines H, Connelly M, Stewart CF, Gould S, Rubin LL, Curran T. Romer JT, et al. Among authors: curran t. Cancer Cell. 2004 Sep;6(3):229-40. doi: 10.1016/j.ccr.2004.08.019. Cancer Cell. 2004. PMID: 15380514 Free article.

3

Targeting medulloblastoma: small-molecule inhibitors of the Sonic Hedgehog pathway as potential cancer therapeutics.

Romer J, Curran T. Romer J, et al. Among authors: curran t. Cancer Res. 2005 Jun 15;65(12):4975-8. doi: 10.1158/0008-5472.CAN-05-0481. Cancer Res. 2005. PMID: 15958535 Review.

4

Glucocorticoid compounds modify smoothened localization and hedgehog pathway activity.

Wang Y, Davidow L, Arvanites AC, Blanchard J, Lam K, Xu K, Oza V, Yoo JW, Ng JM, Curran T, Rubin LL, McMahon AP. Wang Y, et al. Among authors: curran t. Chem Biol. 2012 Aug 24;19(8):972-82. doi: 10.1016/j.chembiol.2012.06.012. Chem Biol. 2012. PMID: 22921064 Free PMC article.

5

Shh pathway activity is down-regulated in cultured medulloblastoma cells: implications for preclinical studies.

Sasai K, Romer JT, Lee Y, Finkelstein D, Fuller C, McKinnon PJ, Curran T. Sasai K, et al. Among authors: curran t. Cancer Res. 2006 Apr 15;66(8):4215-22. doi: 10.1158/0008-5472.CAN-05-4505. Cancer Res. 2006. PMID: 16618744

6

Medulloblastomas derived from Cxcr6 mutant mice respond to treatment with a smoothened inhibitor.

Sasai K, Romer JT, Kimura H, Eberhart DE, Rice DS, Curran T. Sasai K, et al. Among authors: curran t. Cancer Res. 2007 Apr 15;67(8):3871-7. doi: 10.1158/0008-5472.CAN-07-0493. Epub 2007 Apr 5. Cancer Res. 2007. PMID: 17413002

7

Medulloblastoma and retinoblastoma: oncology recapitulates ontogeny.

Romer JT, Curran T. Romer JT, et al. Among authors: curran t. Cell Cycle. 2004 Jul;3(7):917-9. Epub 2004 Jul 8. Cell Cycle. 2004. PMID: 15254429 Review.

8

Role of the reelin signaling pathway in central nervous system development.

Rice DS, Curran T. Rice DS, et al. Among authors: curran t. Annu Rev Neurosci. 2001;24:1005-39. doi: 10.1146/annurev.neuro.24.1.1005. Annu Rev Neurosci. 2001. PMID: 11520926 Review.

9

Transient inhibition of the Hedgehog pathway in young mice causes permanent defects in bone structure.

Kimura H, Ng JM, Curran T. Kimura H, et al. Among authors: curran t. Cancer Cell. 2008 Mar;13(3):249-60. doi: 10.1016/j.ccr.2008.01.027. Cancer Cell. 2008. PMID: 18328428 Free article.

10

PTHrP treatment fails to rescue bone defects caused by Hedgehog pathway inhibition in young mice.

Brechbiel JL, Ng JM, Curran T. Brechbiel JL, et al. Among authors: curran t. Toxicol Pathol. 2011 Apr;39(3):478-85. doi: 10.1177/0192623311399788. Epub 2011 Mar 16. Toxicol Pathol. 2011. PMID: 21411723 Free PMC article.

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