Pardo OE - Search Results

1

Phosphoinositide 3-Kinase C2beta regulates cytoskeletal organization and cell migration via Rac-dependent mechanisms.

Katso RM, Pardo OE, Palamidessi A, Franz CM, Marinov M, De Laurentiis A, Downward J, Scita G, Ridley AJ, Waterfield MD, Arcaro A. Katso RM, et al. Among authors: pardo oe. Mol Biol Cell. 2006 Sep;17(9):3729-44. doi: 10.1091/mbc.e05-11-1083. Epub 2006 Jun 14. Mol Biol Cell. 2006. PMID: 16775008 Free PMC article.

2

Author Correction: Results of the phase IIa RADICAL trial of the FGFR inhibitor AZD4547 in endocrine resistant breast cancer.

Coombes RC, Badman PD, Lozano-Kuehne JP, Liu X, Macpherson IR, Zubairi I, Baird RD, Rosenfeld N, Garcia-Corbacho J, Cresti N, Plummer R, Armstrong A, Allerton R, Landers D, Nicholas H, McLellan L, Lim A, Mouliere F, Pardo OE, Ferguson V, Seckl MJ. Coombes RC, et al. Among authors: pardo oe. Nat Commun. 2023 Jan 17;14(1):260. doi: 10.1038/s41467-023-35969-4. Nat Commun. 2023. PMID: 36650166 Free PMC article. No abstract available.

3

Novel cross talk between MEK and S6K2 in FGF-2 induced proliferation of SCLC cells.

Pardo OE, Arcaro A, Salerno G, Tetley TD, Valovka T, Gout I, Seckl MJ. Pardo OE, et al. Oncogene. 2001 Nov 15;20(52):7658-67. doi: 10.1038/sj.onc.1204994. Oncogene. 2001. PMID: 11753643

4

Fibroblast growth factor-2 induces translational regulation of Bcl-XL and Bcl-2 via a MEK-dependent pathway: correlation with resistance to etoposide-induced apoptosis.

Pardo OE, Arcaro A, Salerno G, Raguz S, Downward J, Seckl MJ. Pardo OE, et al. J Biol Chem. 2002 Apr 5;277(14):12040-6. doi: 10.1074/jbc.M109006200. Epub 2002 Jan 28. J Biol Chem. 2002. Retraction in: J Biol Chem. 2015 Jun 19;290(25):15390. doi: 10.1074/jbc.A115.109006 PMID: 11815602 Free article. Retracted.

5

Fibroblast growth factor 2-mediated translational control of IAPs blocks mitochondrial release of Smac/DIABLO and apoptosis in small cell lung cancer cells.

Pardo OE, Lesay A, Arcaro A, Lopes R, Ng BL, Warne PH, McNeish IA, Tetley TD, Lemoine NR, Mehmet H, Seckl MJ, Downward J. Pardo OE, et al. Mol Cell Biol. 2003 Nov;23(21):7600-10. doi: 10.1128/MCB.23.21.7600-7610.2003. Mol Cell Biol. 2003. PMID: 14560006 Free PMC article.

6

CUTL1 is a target of TGF(beta) signaling that enhances cancer cell motility and invasiveness.

Michl P, Ramjaun AR, Pardo OE, Warne PH, Wagner M, Poulsom R, D'Arrigo C, Ryder K, Menke A, Gress T, Downward J. Michl P, et al. Among authors: pardo oe. Cancer Cell. 2005 Jun;7(6):521-32. doi: 10.1016/j.ccr.2005.05.018. Cancer Cell. 2005. PMID: 15950902 Free article.

7

Potent inhibition of small-cell lung cancer cell growth by simvastatin reveals selective functions of Ras isoforms in growth factor signalling.

Khanzada UK, Pardo OE, Meier C, Downward J, Seckl MJ, Arcaro A. Khanzada UK, et al. Among authors: pardo oe. Oncogene. 2006 Feb 9;25(6):877-87. doi: 10.1038/sj.onc.1209117. Oncogene. 2006. PMID: 16170339

8

FGF-2 protects small cell lung cancer cells from apoptosis through a complex involving PKCepsilon, B-Raf and S6K2.

Pardo OE, Wellbrock C, Khanzada UK, Aubert M, Arozarena I, Davidson S, Bowen F, Parker PJ, Filonenko VV, Gout IT, Sebire N, Marais R, Downward J, Seckl MJ. Pardo OE, et al. EMBO J. 2006 Jul 12;25(13):3078-88. doi: 10.1038/sj.emboj.7601198. Epub 2006 Jun 29. EMBO J. 2006. PMID: 16810323 Free PMC article.

9

Regulators of mitotic arrest and ceramide metabolism are determinants of sensitivity to paclitaxel and other chemotherapeutic drugs.

Swanton C, Marani M, Pardo O, Warne PH, Kelly G, Sahai E, Elustondo F, Chang J, Temple J, Ahmed AA, Brenton JD, Downward J, Nicke B. Swanton C, et al. Cancer Cell. 2007 Jun;11(6):498-512. doi: 10.1016/j.ccr.2007.04.011. Cancer Cell. 2007. PMID: 17560332 Free article.

10

AKT/mTOR pathway activation and BCL-2 family proteins modulate the sensitivity of human small cell lung cancer cells to RAD001.

Marinov M, Ziogas A, Pardo OE, Tan LT, Dhillon T, Mauri FA, Lane HA, Lemoine NR, Zangemeister-Wittke U, Seckl MJ, Arcaro A. Marinov M, et al. Among authors: pardo oe. Clin Cancer Res. 2009 Feb 15;15(4):1277-87. doi: 10.1158/1078-0432.CCR-08-2166. Clin Cancer Res. 2009. PMID: 19228731 Free article.

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