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The relative bioavailability of loratadine administered as a chewing gum formulation in healthy volunteers.
Eur J Clin Pharmacol. 2006 Jun;62(6):437-45. doi: 10.1007/s00228-006-0139-6. Epub 2006 Apr 28.
Eur J Clin Pharmacol. 2006.
PMID: 16770647
Rifampicin seems to act as both an inducer and an inhibitor of the metabolism of repaglinide.
Bidstrup TB, Stilling N, Damkier P, Scharling B, Thomsen MS, Brøsen K.
Bidstrup TB, et al.
Eur J Clin Pharmacol. 2004 Apr;60(2):109-14. doi: 10.1007/s00228-004-0746-z. Epub 2004 Mar 19.
Eur J Clin Pharmacol. 2004.
PMID: 15034704
Clinical Trial.
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The impact of CYP2C8 polymorphism and grapefruit juice on the pharmacokinetics of repaglinide.
Bidstrup TB, Damkier P, Olsen AK, Ekblom M, Karlsson A, Brøsen K.
Bidstrup TB, et al.
Br J Clin Pharmacol. 2006 Jan;61(1):49-57. doi: 10.1111/j.1365-2125.2005.02516.x.
Br J Clin Pharmacol. 2006.
PMID: 16390351
Free PMC article.
Clinical Trial.
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CYP2C8 and CYP3A4 are the principal enzymes involved in the human in vitro biotransformation of the insulin secretagogue repaglinide.
Bidstrup TB, Bjørnsdottir I, Sidelmann UG, Thomsen MS, Hansen KT.
Bidstrup TB, et al.
Br J Clin Pharmacol. 2003 Sep;56(3):305-14. doi: 10.1046/j.0306-5251.2003.01862.x.
Br J Clin Pharmacol. 2003.
PMID: 12919179
Free PMC article.
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