Lozach O - Search Results

1

Synthesis of novel 5-substituted indirubins as protein kinases inhibitors.

Beauchard A, Ferandin Y, Frère S, Lozach O, Blairvacq M, Meijer L, Thiéry V, Besson T. Beauchard A, et al. Among authors: lozach o. Bioorg Med Chem. 2006 Sep 15;14(18):6434-43. doi: 10.1016/j.bmc.2006.05.036. Epub 2006 Jun 8. Bioorg Med Chem. 2006. PMID: 16759872

2

Synthesis and evaluation of the antiproliferative activity of novel thiazoloquinazolinone kinases inhibitors.

Testard A, Picot L, Lozach O, Blairvacq M, Meijer L, Murillo L, Piot JM, Thiéry V, Besson T. Testard A, et al. Among authors: lozach o. J Enzyme Inhib Med Chem. 2005 Dec;20(6):557-68. doi: 10.1080/14756360500212399. J Enzyme Inhib Med Chem. 2005. PMID: 16408791 Free article.

3

Synthesis and biological evaluation of novel phenylcarbazoles as potential anticancer agents.

Routier S, Mérour JY, Dias N, Lansiaux A, Bailly C, Lozach O, Meijer L. Routier S, et al. Among authors: lozach o. J Med Chem. 2006 Jan 26;49(2):789-99. doi: 10.1021/jm050945x. J Med Chem. 2006. PMID: 16420063

4

Suzuki-type Pd(0) coupling reactions in the synthesis of 2-arylpurines as Cdk inhibitors.

Vandromme L, Piguel S, Lozach O, Meijer L, Legraverend M, Grierson DS. Vandromme L, et al. Among authors: lozach o. Bioorg Med Chem Lett. 2006 Jun 15;16(12):3144-6. doi: 10.1016/j.bmcl.2006.03.060. Epub 2006 Apr 17. Bioorg Med Chem Lett. 2006. PMID: 16616489

5

Thiazolo[5,4-f]quinazolin-9-ones, inhibitors of glycogen synthase kinase-3.

Testard A, Logé C, Léger B, Robert JM, Lozach O, Blairvacq M, Meijer L, Thiéry V, Besson T. Testard A, et al. Among authors: lozach o. Bioorg Med Chem Lett. 2006 Jul 1;16(13):3419-23. doi: 10.1016/j.bmcl.2006.04.006. Epub 2006 Apr 27. Bioorg Med Chem Lett. 2006. PMID: 16644220

6

3'-Substituted 7-halogenoindirubins, a new class of cell death inducing agents.

Ferandin Y, Bettayeb K, Kritsanida M, Lozach O, Polychronopoulos P, Magiatis P, Skaltsounis AL, Meijer L. Ferandin Y, et al. Among authors: lozach o. J Med Chem. 2006 Jul 27;49(15):4638-49. doi: 10.1021/jm060314i. J Med Chem. 2006. PMID: 16854069

7

A Pd(0) based cross-coupling approach to the synthesis of 2-amidopurines and their evaluation as CDK inhibitors.

Vandromme L, Legraverend M, Kreimerman S, Lozach O, Meijer L, Grierson DS. Vandromme L, et al. Among authors: lozach o. Bioorg Med Chem. 2007 Jan 1;15(1):130-41. doi: 10.1016/j.bmc.2006.10.003. Epub 2006 Oct 6. Bioorg Med Chem. 2007. PMID: 17064911

8

Novel 9-oxo-thiazolo[5,4-f]quinazoline-2-carbonitrile derivatives as dual cyclin-dependent kinase 1 (CDK1)/glycogen synthase kinase-3 (GSK-3) inhibitors: synthesis, biological evaluation and molecular modeling studies.

Logé C, Testard A, Thiéry V, Lozach O, Blairvacq M, Robert JM, Meijer L, Besson T. Logé C, et al. Among authors: lozach o. Eur J Med Chem. 2008 Jul;43(7):1469-77. doi: 10.1016/j.ejmech.2007.09.020. Epub 2007 Sep 29. Eur J Med Chem. 2008. PMID: 17981370

9

Synthesis of 3,5-bis(2-indolyl)pyridine and 3-[(2-indolyl)-5-phenyl]pyridine derivatives as CDK inhibitors and cytotoxic agents.

Jacquemard U, Dias N, Lansiaux A, Bailly C, Logé C, Robert JM, Lozach O, Meijer L, Mérour JY, Routier S. Jacquemard U, et al. Among authors: lozach o. Bioorg Med Chem. 2008 May 1;16(9):4932-53. doi: 10.1016/j.bmc.2008.03.034. Epub 2008 Mar 17. Bioorg Med Chem. 2008. PMID: 18439832

10

Soluble 3',6-substituted indirubins with enhanced selectivity toward glycogen synthase kinase -3 alter circadian period.

Vougogiannopoulou K, Ferandin Y, Bettayeb K, Myrianthopoulos V, Lozach O, Fan Y, Johnson CH, Magiatis P, Skaltsounis AL, Mikros E, Meijer L. Vougogiannopoulou K, et al. Among authors: lozach o. J Med Chem. 2008 Oct 23;51(20):6421-31. doi: 10.1021/jm800648y. Epub 2008 Sep 25. J Med Chem. 2008. PMID: 18816110 Free PMC article.

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