Barrett MP - Search Results

1

DNA binding affinity of bisguanidine and bis(2-aminoimidazoline) derivatives with in vivo antitrypanosomal activity.

Dardonville C, Barrett MP, Brun R, Kaiser M, Tanious F, Wilson WD. Dardonville C, et al. Among authors: barrett mp. J Med Chem. 2006 Jun 15;49(12):3748-52. doi: 10.1021/jm060295c. J Med Chem. 2006. PMID: 16759117 Free article.

2

An approach to use an unusual adenosine transporter to selectively deliver polyamine analogues to trypanosomes.

Tye CK, Kasinathan G, Barrett MP, Brun R, Doyle VE, Fairlamb AH, Weaver R, Gilbert IH. Tye CK, et al. Among authors: barrett mp. Bioorg Med Chem Lett. 1998 Apr 7;8(7):811-6. doi: 10.1016/s0960-894x(98)00095-x. Bioorg Med Chem Lett. 1998. PMID: 9871546

3

Synthesis and biological evaluation of s-triazine substituted polyamines as potential new anti-trypanosomal drugs.

Klenke B, Stewart M, Barrett MP, Brun R, Gilbert IH. Klenke B, et al. Among authors: barrett mp. J Med Chem. 2001 Oct 11;44(21):3440-52. doi: 10.1021/jm010854+. J Med Chem. 2001. PMID: 11585449

4

Synthesis and biological evaluation of substrate-based inhibitors of 6-phosphogluconate dehydrogenase as potential drugs against African trypanosomiasis.

Dardonville C, Rinaldi E, Hanau S, Barrett MP, Brun R, Gilbert IH. Dardonville C, et al. Among authors: barrett mp. Bioorg Med Chem. 2003 Jul 17;11(14):3205-14. doi: 10.1016/s0968-0896(03)00191-3. Bioorg Med Chem. 2003. PMID: 12818683

5

Antiplasmodial activity of a series of 1,3,5-triazine-substituted polyamines.

Klenke B, Barrett MP, Brun R, Gilbert IH. Klenke B, et al. Among authors: barrett mp. J Antimicrob Chemother. 2003 Aug;52(2):290-3. doi: 10.1093/jac/dkg307. Epub 2003 Jul 1. J Antimicrob Chemother. 2003. PMID: 12837742

6

Mechanisms of arsenical and diamidine uptake and resistance in Trypanosoma brucei.

Matovu E, Stewart ML, Geiser F, Brun R, Mäser P, Wallace LJ, Burchmore RJ, Enyaru JC, Barrett MP, Kaminsky R, Seebeck T, de Koning HP. Matovu E, et al. Among authors: barrett mp. Eukaryot Cell. 2003 Oct;2(5):1003-8. doi: 10.1128/EC.2.5.1003-1008.2003. Eukaryot Cell. 2003. PMID: 14555482 Free PMC article.

7

Trypanocidal activity of melamine-based nitroheterocycles.

Stewart ML, Bueno GJ, Baliani A, Klenke B, Brun R, Brock JM, Gilbert IH, Barrett MP. Stewart ML, et al. Among authors: barrett mp. Antimicrob Agents Chemother. 2004 May;48(5):1733-8. doi: 10.1128/AAC.48.5.1733-1738.2004. Antimicrob Agents Chemother. 2004. PMID: 15105128 Free PMC article.

8

Selective inhibition of Trypanosoma brucei 6-phosphogluconate dehydrogenase by high-energy intermediate and transition-state analogues.

Dardonville C, Rinaldi E, Barrett MP, Brun R, Gilbert IH, Hanau S. Dardonville C, et al. Among authors: barrett mp. J Med Chem. 2004 Jun 17;47(13):3427-37. doi: 10.1021/jm031066i. J Med Chem. 2004. PMID: 15189039

9

6-phosphogluconate dehydrogenase: a target for drugs in African trypanosomes.

Hanau S, Rinaldi E, Dallocchio F, Gilbert IH, Dardonville C, Adams MJ, Gover S, Barrett MP. Hanau S, et al. Among authors: barrett mp. Curr Med Chem. 2004 Oct;11(19):2639-50. doi: 10.2174/0929867043364441. Curr Med Chem. 2004. PMID: 15544466 Review.

10

Detection of arsenical drug resistance in Trypanosoma brucei with a simple fluorescence test.

Stewart ML, Krishna S, Burchmore RJ, Brun R, de Koning HP, Boykin DW, Tidwell RR, Hall JE, Barrett MP. Stewart ML, et al. Among authors: barrett mp. Lancet. 2005 Aug 6-12;366(9484):486-7. doi: 10.1016/S0140-6736(05)66793-1. Lancet. 2005. PMID: 16084257

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