Appel JR - Search Results

1

Identification of potent and highly selective chiral tri-amine and tetra-amine mu opioid receptors ligands: an example of lead optimization using mixture-based libraries.

Nefzi A, Ostresh JM, Appel JR, Bidlack J, Dooley CT, Houghten RA. Nefzi A, et al. Among authors: appel jr. Bioorg Med Chem Lett. 2006 Aug 15;16(16):4331-8. doi: 10.1016/j.bmcl.2006.05.053. Epub 2006 Jun 5. Bioorg Med Chem Lett. 2006. PMID: 16750366

2

Anomalous reversed-phase high-performance liquid chromatographic behavior of synthetic peptides related to antigenic helper T cell sites.

Büttner K, Pinilla C, Appel JR, Houghten RA. Büttner K, et al. Among authors: appel jr. J Chromatogr. 1992 Nov 20;625(2):191-8. doi: 10.1016/0021-9673(92)85202-5. J Chromatogr. 1992. PMID: 1282129

3

The use of synthetic peptide combinatorial libraries for the identification of bioactive peptides.

Houghten RA, Appel JR, Blondelle SE, Cuervo JH, Dooley CT, Pinilla C. Houghten RA, et al. Among authors: appel jr. Biotechniques. 1992 Sep;13(3):412-21. Biotechniques. 1992. PMID: 1382470

4

Rapid identification of high affinity peptide ligands using positional scanning synthetic peptide combinatorial libraries.

Pinilla C, Appel JR, Blanc P, Houghten RA. Pinilla C, et al. Among authors: appel jr. Biotechniques. 1992 Dec;13(6):901-5. Biotechniques. 1992. PMID: 1476743

5

Elucidation of discontinuous linear determinants in peptides.

Appel JR, Pinilla C, Niman H, Houghten R. Appel JR, et al. J Immunol. 1990 Feb 1;144(3):976-83. J Immunol. 1990. PMID: 1688594

6

Generation and use of synthetic peptide combinatorial libraries for basic research and drug discovery.

Houghten RA, Pinilla C, Blondelle SE, Appel JR, Dooley CT, Cuervo JH. Houghten RA, et al. Among authors: appel jr. Nature. 1991 Nov 7;354(6348):84-6. doi: 10.1038/354084a0. Nature. 1991. PMID: 1719428

7

Investigation of antigen-antibody interactions using a soluble, non-support-bound synthetic decapeptide library composed of four trillion (4 x 10(12) sequences.

Pinilla C, Appel JR, Houghten RA. Pinilla C, et al. Among authors: appel jr. Biochem J. 1994 Aug 1;301 ( Pt 3)(Pt 3):847-53. doi: 10.1042/bj3010847. Biochem J. 1994. PMID: 7519851 Free PMC article.

8

Crystal structure of a peptide complex of anti-influenza peptide antibody Fab 26/9. Comparison of two different antibodies bound to the same peptide antigen.

Churchill ME, Stura EA, Pinilla C, Appel JR, Houghten RA, Kono DH, Balderas RS, Fieser GG, Schulze-Gahmen U, Wilson IA. Churchill ME, et al. Among authors: appel jr. J Mol Biol. 1994 Aug 26;241(4):534-56. doi: 10.1006/jmbi.1994.1530. J Mol Biol. 1994. PMID: 7520084

9

Activation of bee venom phospholipase A2 through a peptide-enzyme complex.

Mingarro I, Pérez-Payá E, Pinilla C, Appel JR, Houghten RA, Blondelle SE. Mingarro I, et al. Among authors: appel jr. FEBS Lett. 1995 Sep 18;372(1):131-4. doi: 10.1016/0014-5793(95)00964-b. FEBS Lett. 1995. PMID: 7556634 Free article.

10

Functional importance of amino acid residues making up peptide antigenic determinants.

Pinilla C, Appel JR, Houghten RA. Pinilla C, et al. Among authors: appel jr. Mol Immunol. 1993 Apr;30(6):577-85. doi: 10.1016/0161-5890(93)90032-7. Mol Immunol. 1993. PMID: 7683750

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