Ke H - Search Results

1

Multiple conformations of phosphodiesterase-5: implications for enzyme function and drug development.

Wang H, Liu Y, Huai Q, Cai J, Zoraghi R, Francis SH, Corbin JD, Robinson H, Xin Z, Lin G, Ke H. Wang H, et al. Among authors: ke h. J Biol Chem. 2006 Jul 28;281(30):21469-21479. doi: 10.1074/jbc.M512527200. Epub 2006 May 30. J Biol Chem. 2006. PMID: 16735511 Free article.

2

Crystal structure of NaeI-an evolutionary bridge between DNA endonuclease and topoisomerase.

Huai Q, Colandene JD, Chen Y, Luo F, Zhao Y, Topal MD, Ke H. Huai Q, et al. Among authors: ke h. EMBO J. 2000 Jun 15;19(12):3110-8. doi: 10.1093/emboj/19.12.3110. EMBO J. 2000. PMID: 10856254 Free PMC article.

3

Crystal structures of 1-aminocyclopropane-1-carboxylate (ACC) synthase in complex with aminoethoxyvinylglycine and pyridoxal-5'-phosphate provide new insight into catalytic mechanisms.

Huai Q, Xia Y, Chen Y, Callahan B, Li N, Ke H. Huai Q, et al. Among authors: ke h. J Biol Chem. 2001 Oct 12;276(41):38210-6. doi: 10.1074/jbc.M103840200. Epub 2001 Jun 28. J Biol Chem. 2001. PMID: 11431475 Free article.

4

Structure of NaeI-DNA complex reveals dual-mode DNA recognition and complete dimer rearrangement.

Huai Q, Colandene JD, Topal MD, Ke H. Huai Q, et al. Among authors: ke h. Nat Struct Biol. 2001 Aug;8(8):665-9. doi: 10.1038/90366. Nat Struct Biol. 2001. PMID: 11473254

5

Crystal structure of calcineurin-cyclophilin-cyclosporin shows common but distinct recognition of immunophilin-drug complexes.

Huai Q, Kim HY, Liu Y, Zhao Y, Mondragon A, Liu JO, Ke H. Huai Q, et al. Among authors: ke h. Proc Natl Acad Sci U S A. 2002 Sep 17;99(19):12037-42. doi: 10.1073/pnas.192206699. Epub 2002 Sep 6. Proc Natl Acad Sci U S A. 2002. PMID: 12218175 Free PMC article.

6

Three-dimensional structures of PDE4D in complex with roliprams and implication on inhibitor selectivity.

Huai Q, Wang H, Sun Y, Kim HY, Liu Y, Ke H. Huai Q, et al. Among authors: ke h. Structure. 2003 Jul;11(7):865-73. doi: 10.1016/s0969-2126(03)00123-0. Structure. 2003. PMID: 12842049 Free article.

7

Crystal structure of DJ-1/RS and implication on familial Parkinson's disease.

Huai Q, Sun Y, Wang H, Chin LS, Li L, Robinson H, Ke H. Huai Q, et al. Among authors: ke h. FEBS Lett. 2003 Aug 14;549(1-3):171-5. doi: 10.1016/s0014-5793(03)00764-6. FEBS Lett. 2003. PMID: 12914946 Free article.

8

The crystal structure of AMP-bound PDE4 suggests a mechanism for phosphodiesterase catalysis.

Huai Q, Colicelli J, Ke H. Huai Q, et al. Among authors: ke h. Biochemistry. 2003 Nov 18;42(45):13220-6. doi: 10.1021/bi034653e. Biochemistry. 2003. PMID: 14609333

9

Structures of calcineurin and its complexes with immunophilins-immunosuppressants.

Ke H, Huai Q. Ke H, et al. Biochem Biophys Res Commun. 2003 Nov 28;311(4):1095-102. doi: 10.1016/s0006-291x(03)01537-7. Biochem Biophys Res Commun. 2003. PMID: 14623295 Review.

10

Familial Parkinson's disease-associated L166P mutation disrupts DJ-1 protein folding and function.

Olzmann JA, Brown K, Wilkinson KD, Rees HD, Huai Q, Ke H, Levey AI, Li L, Chin LS. Olzmann JA, et al. Among authors: ke h. J Biol Chem. 2004 Feb 27;279(9):8506-15. doi: 10.1074/jbc.M311017200. Epub 2003 Dec 9. J Biol Chem. 2004. PMID: 14665635 Free article.

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