Brun R - Search Results

1

In vitro assessment of the pharmacodynamic properties and the partitioning of OZ277/RBx-11160 in cultures of Plasmodium falciparum.

Maerki S, Brun R, Charman SA, Dorn A, Matile H, Wittlin S. Maerki S, et al. Among authors: brun r. J Antimicrob Chemother. 2006 Jul;58(1):52-8. doi: 10.1093/jac/dkl209. Epub 2006 May 30. J Antimicrob Chemother. 2006. PMID: 16735432

2

Peroxide bond-dependent antiplasmodial specificity of artemisinin and OZ277 (RBx11160).

Kaiser M, Wittlin S, Nehrbass-Stuedli A, Dong Y, Wang X, Hemphill A, Matile H, Brun R, Vennerstrom JL. Kaiser M, et al. Among authors: brun r. Antimicrob Agents Chemother. 2007 Aug;51(8):2991-3. doi: 10.1128/AAC.00225-07. Epub 2007 Jun 11. Antimicrob Agents Chemother. 2007. PMID: 17562801 Free PMC article.

3

In vitro assessment of the pharmacodynamic properties of DB75, piperaquine, OZ277 and OZ401 in cultures of Plasmodium falciparum.

Hofer S, Brun R, Maerki S, Matile H, Scheurer C, Wittlin S. Hofer S, et al. Among authors: brun r. J Antimicrob Chemother. 2008 Nov;62(5):1061-4. doi: 10.1093/jac/dkn315. Epub 2008 Jul 30. J Antimicrob Chemother. 2008. PMID: 18669520 Free article.

4

In vitro and in vivo characterization of the antimalarial lead compound SSJ-183 in Plasmodium models.

Schleiferböck S, Scheurer C, Ihara M, Itoh I, Bathurst I, Burrows JN, Fantauzzi P, Lotharius J, Charman SA, Morizzi J, Shackleford DM, White KL, Brun R, Wittlin S. Schleiferböck S, et al. Among authors: brun r. Drug Des Devel Ther. 2013 Nov 15;7:1377-84. doi: 10.2147/DDDT.S51298. eCollection 2013. Drug Des Devel Ther. 2013. PMID: 24255594 Free PMC article.

5

A new double-antibody sandwich ELISA targeting Plasmodium falciparum aldolase to evaluate anti-malarial drug sensitivity.

Tritten L, Matile H, Brun R, Wittlin S. Tritten L, et al. Among authors: brun r. Malar J. 2009 Oct 12;8:226. doi: 10.1186/1475-2875-8-226. Malar J. 2009. PMID: 19821995 Free PMC article.

6

The structure-activity relationship of the antimalarial ozonide arterolane (OZ277).

Dong Y, Wittlin S, Sriraghavan K, Chollet J, Charman SA, Charman WN, Scheurer C, Urwyler H, Santo Tomas J, Snyder C, Creek DJ, Morizzi J, Koltun M, Matile H, Wang X, Padmanilayam M, Tang Y, Dorn A, Brun R, Vennerstrom JL. Dong Y, et al. Among authors: brun r. J Med Chem. 2010 Jan 14;53(1):481-91. doi: 10.1021/jm901473s. J Med Chem. 2010. PMID: 19924861

7

Isothermal microcalorimetry, a new tool to monitor drug action against Trypanosoma brucei and Plasmodium falciparum.

Wenzler T, Steinhuber A, Wittlin S, Scheurer C, Brun R, Trampuz A. Wenzler T, et al. Among authors: brun r. PLoS Negl Trop Dis. 2012;6(6):e1668. doi: 10.1371/journal.pntd.0001668. Epub 2012 Jun 5. PLoS Negl Trop Dis. 2012. PMID: 22679520 Free PMC article.

8

In vitro interaction of artemisinin derivatives or the fully synthetic peroxidic anti-malarial OZ277 with thapsigargin in Plasmodium falciparum strains.

Abiodun OO, Brun R, Wittlin S. Abiodun OO, et al. Among authors: brun r. Malar J. 2013 Jan 31;12:43. doi: 10.1186/1475-2875-12-43. Malar J. 2013. PMID: 23368889 Free PMC article.

9

Plasmodium vivax: in vitro susceptibility of blood stages to synthetic trioxolane compounds and the diamidine DB75.

Kocken CH, van der Wel A, Arbe-Barnes S, Brun R, Matile H, Scheurer C, Wittlin S, Thomas AW. Kocken CH, et al. Among authors: brun r. Exp Parasitol. 2006 Jul;113(3):197-200. doi: 10.1016/j.exppara.2005.12.016. Epub 2006 Feb 3. Exp Parasitol. 2006. PMID: 16458301

10

In vitro susceptibility of P. falciparum populations from Colombia and Tanzania to a new synthetic peroxide (OZ277).

Osorio L, Murillo C, Aponte S, Mayagaya V, Scheurer C, Brun R, Matile H, Wittlin S. Osorio L, et al. Among authors: brun r. Am J Trop Med Hyg. 2007 Jun;76(6):1024-6. Am J Trop Med Hyg. 2007. PMID: 17556605

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