Marquez VE - Search Results

1

Conformationally constrained analogues of diacylglycerol. 26. Exploring the chemical space surrounding the C1 domain of protein kinase C with DAG-lactones containing aryl groups at the sn-1 and sn-2 positions.

Kang JH, Benzaria S, Sigano DM, Lewin NE, Pu Y, Peach ML, Blumberg PM, Marquez VE. Kang JH, et al. Among authors: marquez ve. J Med Chem. 2006 Jun 1;49(11):3185-203. doi: 10.1021/jm060011o. J Med Chem. 2006. PMID: 16722637

2

Differential binding modes of diacylglycerol (DAG) and DAG lactones to protein kinase C (PK-C).

Sigano DM, Peach ML, Nacro K, Choi Y, Lewin NE, Nicklaus MC, Blumberg PM, Marquez VE. Sigano DM, et al. Among authors: marquez ve. J Med Chem. 2003 Apr 24;46(9):1571-9. doi: 10.1021/jm020476o. J Med Chem. 2003. PMID: 12699375

3

Conformationally constrained analogues of diacylglycerol (DAG). Effect on protein kinase C (PK-C) binding by the isosteric replacement of sn-1 and sn-2 esters in DAG-lactones.

Kang JH, Chung HE, Kim SY, Kim Y, Lee J, Lewin NE, Pearce LV, Blumberg PM, Marquez VE. Kang JH, et al. Among authors: marquez ve. Bioorg Med Chem. 2003 Jun 12;11(12):2529-39. doi: 10.1016/s0968-0896(03)00156-1. Bioorg Med Chem. 2003. PMID: 12757721

4

Conformationally constrained analogues of diacylglycerol. 19. Synthesis and protein kinase C binding affinity of diacylglycerol lactones bearing an N-hydroxylamide side chain.

Choi Y, Kang JH, Lewin NE, Blumberg PM, Lee J, Marquez VE. Choi Y, et al. Among authors: marquez ve. J Med Chem. 2003 Jun 19;46(13):2790-3. doi: 10.1021/jm030082c. J Med Chem. 2003. PMID: 12801241

5

Synthetic diacylglycerols (DAG) and DAG-lactones as activators of protein kinase C (PK-C).

Marquez VE, Blumberg PM. Marquez VE, et al. Acc Chem Res. 2003 Jun;36(6):434-43. doi: 10.1021/ar020124b. Acc Chem Res. 2003. PMID: 12809530 Review.

6

Conformationally constrained analogues of diacylglycerol. 20. The search for an elusive binding site on protein kinase C through relocation of the carbonyl pharmacophore along the sn-1 side chain of 1,2-diacylglycerol lactones.

Tamamura H, Sigano DM, Lewin NE, Blumberg PM, Marquez VE. Tamamura H, et al. Among authors: marquez ve. J Med Chem. 2004 Jan 29;47(3):644-55. doi: 10.1021/jm030454h. J Med Chem. 2004. PMID: 14736244

7

Conformationally constrained diacylglycerol (DAG) analogs: 4-C-hydroxyethyl-5-O-acyl-2,3-dideoxy-D-glyceropentono-1,4-lactone analogs as protein kinase C (PKC) ligands.

Lee J, Kim SY, Kang JH, Acs G, Acs P, Blumberg PM, Marquez VE. Lee J, et al. Among authors: marquez ve. Eur J Med Chem. 2004 Jan;39(1):69-77. doi: 10.1016/j.ejmech.2003.10.006. Eur J Med Chem. 2004. PMID: 14987835

8

Conformationally constrained analogues of diacylglycerol. 21. A solid-phase method of synthesis of diacylglycerol lactones as a prelude to a combinatorial approach for the synthesis of protein kinase C isozyme-specific ligands.

Duan D, Lewin NE, Sigano DM, Blumberg PM, Marquez VE. Duan D, et al. Among authors: marquez ve. J Med Chem. 2004 Jun 3;47(12):3248-54. doi: 10.1021/jm030610k. J Med Chem. 2004. PMID: 15163204

9

Conformationally constrained analogues of diacylglycerol. 24. Asymmetric synthesis of a chiral (R)-DAG-lactone template as a versatile precursor for highly functionalized DAG-lactones.

Kang JH, Siddiqui MA, Sigano DM, Krajewski K, Lewin NE, Pu Y, Blumberg PM, Lee J, Marquez VE. Kang JH, et al. Among authors: marquez ve. Org Lett. 2004 Jul 8;6(14):2413-6. doi: 10.1021/ol0492041. Org Lett. 2004. PMID: 15228292

10

Macrocyclic diacylglycerol-bis-lactones as conformationally constrained analogues of diacylglycerol-lactones. Interactions with protein kinase C.

Kang JH, Kim SY, Lee J, Marquez VE, Lewin NE, Pearce LV, Blumberg PM. Kang JH, et al. Among authors: marquez ve. J Med Chem. 2004 Jul 29;47(16):4000-7. doi: 10.1021/jm0497747. J Med Chem. 2004. PMID: 15267238

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

325 results

Search Page

Filters