Cavener DR - Search Results

1

Mutations in GLIS3 are responsible for a rare syndrome with neonatal diabetes mellitus and congenital hypothyroidism.

Senée V, Chelala C, Duchatelet S, Feng D, Blanc H, Cossec JC, Charon C, Nicolino M, Boileau P, Cavener DR, Bougnères P, Taha D, Julier C. Senée V, et al. Among authors: cavener dr. Nat Genet. 2006 Jun;38(6):682-7. doi: 10.1038/ng1802. Epub 2006 May 21. Nat Genet. 2006. PMID: 16715098

2

PERK EIF2AK3 control of pancreatic beta cell differentiation and proliferation is required for postnatal glucose homeostasis.

Zhang W, Feng D, Li Y, Iida K, McGrath B, Cavener DR. Zhang W, et al. Among authors: cavener dr. Cell Metab. 2006 Dec;4(6):491-7. doi: 10.1016/j.cmet.2006.11.002. Cell Metab. 2006. PMID: 17141632 Free article.

3

PERK is essential for neonatal skeletal development to regulate osteoblast proliferation and differentiation.

Wei J, Sheng X, Feng D, McGrath B, Cavener DR. Wei J, et al. Among authors: cavener dr. J Cell Physiol. 2008 Dec;217(3):693-707. doi: 10.1002/jcp.21543. J Cell Physiol. 2008. PMID: 18683826

4

Acute ablation of PERK results in ER dysfunctions followed by reduced insulin secretion and cell proliferation.

Feng D, Wei J, Gupta S, McGrath BC, Cavener DR. Feng D, et al. Among authors: cavener dr. BMC Cell Biol. 2009 Sep 4;10:61. doi: 10.1186/1471-2121-10-61. BMC Cell Biol. 2009. PMID: 19732428 Free PMC article.

5

The protein kinase PERK/EIF2AK3 regulates proinsulin processing not via protein synthesis but by controlling endoplasmic reticulum chaperones.

Sowers CR, Wang R, Bourne RA, McGrath BC, Hu J, Bevilacqua SC, Paton JC, Paton AW, Collardeau-Frachon S, Nicolino M, Cavener DR. Sowers CR, et al. Among authors: cavener dr. J Biol Chem. 2018 Apr 6;293(14):5134-5149. doi: 10.1074/jbc.M117.813790. Epub 2018 Feb 14. J Biol Chem. 2018. PMID: 29444822 Free PMC article.

6

Isolation of the gene encoding the Drosophila melanogaster homolog of the Saccharomyces cerevisiae GCN2 eIF-2alpha kinase.

Olsen DS, Jordan B, Chen D, Wek RC, Cavener DR. Olsen DS, et al. Among authors: cavener dr. Genetics. 1998 Jul;149(3):1495-509. doi: 10.1093/genetics/149.3.1495. Genetics. 1998. PMID: 9649537 Free PMC article.

7

The PERK eukaryotic initiation factor 2 alpha kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreas.

Zhang P, McGrath B, Li S, Frank A, Zambito F, Reinert J, Gannon M, Ma K, McNaughton K, Cavener DR. Zhang P, et al. Among authors: cavener dr. Mol Cell Biol. 2002 Jun;22(11):3864-74. doi: 10.1128/MCB.22.11.3864-3874.2002. Mol Cell Biol. 2002. PMID: 11997520 Free PMC article.

8

PERK (eIF2alpha kinase) is required to activate the stress-activated MAPKs and induce the expression of immediate-early genes upon disruption of ER calcium homoeostasis.

Liang SH, Zhang W, McGrath BC, Zhang P, Cavener DR. Liang SH, et al. Among authors: cavener dr. Biochem J. 2006 Jan 1;393(Pt 1):201-9. doi: 10.1042/BJ20050374. Biochem J. 2006. PMID: 16124869 Free PMC article.

9

PERK eIF2 alpha kinase is required to regulate the viability of the exocrine pancreas in mice.

Iida K, Li Y, McGrath BC, Frank A, Cavener DR. Iida K, et al. Among authors: cavener dr. BMC Cell Biol. 2007 Aug 29;8:38. doi: 10.1186/1471-2121-8-38. BMC Cell Biol. 2007. PMID: 17727724 Free PMC article.

10

PERK regulates the proliferation and development of insulin-secreting beta-cell tumors in the endocrine pancreas of mice.

Gupta S, McGrath B, Cavener DR. Gupta S, et al. Among authors: cavener dr. PLoS One. 2009 Nov 24;4(11):e8008. doi: 10.1371/journal.pone.0008008. PLoS One. 2009. PMID: 19956728 Free PMC article.

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