Narumi T - Search Results

1

Synthesis of (Z)-alkene and (E)-fluoroalkene-containing diketopiperazine mimetics utilizing organocopper-mediated reduction-alkylation and diastereoselectivity examination using DFT calculations.

Niida A, Mizumoto M, Narumi T, Inokuchi E, Oishi S, Ohno H, Otaka A, Kitaura K, Fujii N. Niida A, et al. Among authors: narumi t. J Org Chem. 2006 May 26;71(11):4118-29. doi: 10.1021/jo060202z. J Org Chem. 2006. PMID: 16709051

2

A novel one-pot reaction involving organocopper-mediated reduction/transmetalation/asymmetric alkylation, leading to the diastereoselective synthesis of functionalized (Z)-fluoroalkene dipeptide isosteres.

Narumi T, Niida A, Tomita K, Oishi S, Otaka A, Ohno H, Fujii N. Narumi T, et al. Chem Commun (Camb). 2006 Dec 7;(45):4720-2. doi: 10.1039/b608596b. Epub 2006 Sep 28. Chem Commun (Camb). 2006. PMID: 17109048

3

Fmoc-based solid-phase synthesis of GPR54-agonistic pentapeptide derivatives containing alkene- and fluoroalkene-dipeptide isosteres.

Tomita K, Narumi T, Niida A, Oishi S, Ohno H, Fujii N. Tomita K, et al. Among authors: narumi t. Biopolymers. 2007;88(2):272-8. doi: 10.1002/bip.20676. Biopolymers. 2007. PMID: 17216632

4

Facile synthesis of fluoroalkenes by palladium-catalyzed reductive defluorination of allylic gem-difluorides.

Narumi T, Tomita K, Inokuchi E, Kobayashi K, Oishi S, Ohno H, Fujii N. Narumi T, et al. Org Lett. 2007 Aug 16;9(17):3465-8. doi: 10.1021/ol701627v. Epub 2007 Jul 27. Org Lett. 2007. PMID: 17655320

5

Efficient synthesis of trifluoromethyl and related trisubstituted alkene dipeptide isosteres by palladium-catalyzed carbonylation of amino acid derived allylic carbonates.

Inokuchi E, Narumi T, Niida A, Kobayashi K, Tomita K, Oishi S, Ohno H, Fujii N. Inokuchi E, et al. Among authors: narumi t. J Org Chem. 2008 May 16;73(10):3942-5. doi: 10.1021/jo702318d. Epub 2008 Apr 16. J Org Chem. 2008. PMID: 18412390

6

Synthesis of fluoroalkene dipeptide isosteres by an intramolecular redox reaction utilizing N-heteorocyclic carbenes (NHCs).

Yamaki Y, Shigenaga A, Tomita K, Narumi T, Fujii N, Otaka A. Yamaki Y, et al. Among authors: narumi t. J Org Chem. 2009 May 1;74(9):3272-7. doi: 10.1021/jo900134k. J Org Chem. 2009. PMID: 19331367

7

Synthesis and application of (Z)-alkene- and (E)-fluoroalkene-dipeptide isosteres as cis-amide equivalents.

Tomita K, Narumi T, Niida A, Oishi S, Ohno H, Fujii N. Tomita K, et al. Among authors: narumi t. Adv Exp Med Biol. 2009;611:365-6. doi: 10.1007/978-0-387-73657-0_161. Adv Exp Med Biol. 2009. PMID: 19400228 No abstract available.

8

Amino acid-based synthesis of trifluoromethylalkene dipeptide isosteres by alcohol-assisted nucleophilic trifluoromethylation and organozinc-copper-mediated S(N)2' alkylation.

Kobayashi K, Narumi T, Oishi S, Ohno H, Fujii N. Kobayashi K, et al. Among authors: narumi t. J Org Chem. 2009 Jun 19;74(12):4626-9. doi: 10.1021/jo9005602. J Org Chem. 2009. PMID: 19445465

9

Peptide bond mimicry by (E)-alkene and (Z)-fluoroalkene peptide isosteres: synthesis and bioevaluation of alpha-helical anti-HIV peptide analogues.

Oishi S, Kamitani H, Kodera Y, Watanabe K, Kobayashi K, Narumi T, Tomita K, Ohno H, Naito T, Kodama E, Matsuoka M, Fujii N. Oishi S, et al. Among authors: narumi t. Org Biomol Chem. 2009 Jul 21;7(14):2872-7. doi: 10.1039/b907983a. Epub 2009 Jun 4. Org Biomol Chem. 2009. PMID: 19582296

10

Structure-activity relationship study on artificial CXCR4 ligands possessing the cyclic pentapeptide scaffold: the exploration of amino acid residues of pentapeptides by substitutions of several aromatic amino acids.

Tanaka T, Nomura W, Narumi T, Esaka A, Oishi S, Ohashi N, Itotani K, Evans BJ, Wang ZX, Peiper SC, Fujii N, Tamamura H. Tanaka T, et al. Among authors: narumi t. Org Biomol Chem. 2009 Sep 21;7(18):3805-9. doi: 10.1039/b908286g. Epub 2009 Jul 20. Org Biomol Chem. 2009. PMID: 19707686

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