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Neuronal lipid droplets play a conserved and sex-biased role in maintaining whole-body energy homeostasis.
Manceau R, Majeur D, Cherian CM, Miller CJ, Wat LW, Fisher JD, Labarre A, Hollman S, Prakash S, Audet S, Chao CF, Depaauw-Holt L, Rogers B, Bosson A, Xi JJY, Callow CAS, Yoosefi N, Shahraki N, Xia YH, Hui A, VanderZwaag J, Bouyakdan K, Rodaros D, Kotchetkov P, Daneault C, Fallahpour G, Tetreault M, Tremblay MÈ, Ruiz M, Lacoste B, Parker JA, Murphy-Royal C, Huan T, Fulton S, Rideout EJ, Alquier T. Manceau R, et al. Among authors: alquier t. bioRxiv [Preprint]. 2024 Sep 20:2024.09.19.613929. doi: 10.1101/2024.09.19.613929. bioRxiv. 2024. PMID: 39345476 Free PMC article. Preprint.
Blockage of ATGL-mediated breakdown of lipid droplets in microglia alleviates neuroinflammatory and behavioural responses to lipopolysaccharides.
Robb JL, Boisjoly F, Machuca-Parra AI, Coursan A, Manceau R, Majeur D, Rodaros D, Bouyakdan K, Greffard K, Bilodeau JF, Forest A, Daneault C, Ruiz M, Laurent C, Arbour N, Layé S, Fioramonti X, Madore C, Fulton S, Alquier T; Representative of consortium. Robb JL, et al. Among authors: alquier t. Brain Behav Immun. 2025 Jan;123:315-333. doi: 10.1016/j.bbi.2024.09.027. Epub 2024 Sep 24. Brain Behav Immun. 2025. PMID: 39326768 Free article.
16p11.2 haploinsufficiency reduces mitochondrial biogenesis in brain endothelial cells and alters brain metabolism in adult mice.
Béland-Millar A, Kirby A, Truong Y, Ouellette J, Yandiev S, Bouyakdan K, Pileggi C, Naz S, Yin M, Carrier M, Kotchetkov P, St-Pierre MK, Tremblay MÈ, Courchet J, Harper ME, Alquier T, Messier C, Shuhendler AJ, Lacoste B. Béland-Millar A, et al. Among authors: alquier t. Cell Rep. 2023 May 30;42(5):112485. doi: 10.1016/j.celrep.2023.112485. Epub 2023 May 6. Cell Rep. 2023. PMID: 37149866 Free article.
56 results