Sasaki T - Search Results

1

In vitro sensitivity to platinum-derived drugs is associated with expression of thymidylate synthase and dihydropyrimidine dehydrogenase in human lung cancer.

Takizawa M, Kawakami K, Obata T, Matsumoto I, Ohta Y, Oda M, Sasaki T, Watanabe G. Takizawa M, et al. Among authors: sasaki t. Oncol Rep. 2006 Jun;15(6):1533-9. Oncol Rep. 2006. PMID: 16685392

2

[The association of expression and gene polymorphism of the thymidylate synthase gene with 5-fluoro-5'-deoxyuridine sensitivity in gastric cancer cell lines].

Kaneko M, Kawakami K, Oyama K, Endo Y, Tanaka M, Sasaki T, Watanabe G. Kaneko M, et al. Among authors: sasaki t. Gan To Kagaku Ryoho. 2004 Sep;31(9):1347-50. Gan To Kagaku Ryoho. 2004. PMID: 15446554 Japanese.

3

A crucial role of uridine/cytidine kinase 2 in antitumor activity of 3'-ethynyl nucleosides.

Murata D, Endo Y, Obata T, Sakamoto K, Syouji Y, Kadohira M, Matsuda A, Sasaki T. Murata D, et al. Among authors: sasaki t. Drug Metab Dispos. 2004 Oct;32(10):1178-82. doi: 10.1124/dmd.104.000737. Epub 2004 Jul 27. Drug Metab Dispos. 2004. PMID: 15280220

4

Development of an antitumor adenosine analog, 3''-ethynyladenosine.

Endo Y, Obata T, Nomura M, Fukushima M, Yamada Y, Matsuda A, Sasaki T. Endo Y, et al. Among authors: sasaki t. Nucleosides Nucleotides Nucleic Acids. 2007;26(6-7):691-4. doi: 10.1080/15257770701490654. Nucleosides Nucleotides Nucleic Acids. 2007. PMID: 18066881

5

Influence of cytidine deaminase on antitumor activity of 2'-deoxycytidine analogs in vitro and in vivo.

Yoshida T, Endo Y, Obata T, Kosugi Y, Sakamoto K, Sasaki T. Yoshida T, et al. Among authors: sasaki t. Drug Metab Dispos. 2010 Oct;38(10):1814-9. doi: 10.1124/dmd.110.034397. Epub 2010 Jun 29. Drug Metab Dispos. 2010. PMID: 20587622

6

Rapamycin-induced translational derepression of GCN4 mRNA involves a novel mechanism for activation of the eIF2 alpha kinase GCN2.

Kubota H, Obata T, Ota K, Sasaki T, Ito T. Kubota H, et al. Among authors: sasaki t. J Biol Chem. 2003 Jun 6;278(23):20457-60. doi: 10.1074/jbc.C300133200. Epub 2003 Apr 2. J Biol Chem. 2003. PMID: 12676950 Free article.

7

The molecular targets of antitumor 2'-deoxycytidine analogues.

Obata T, Endo Y, Murata D, Sakamoto K, Sasaki T. Obata T, et al. Among authors: sasaki t. Curr Drug Targets. 2003 May;4(4):305-13. doi: 10.2174/1389450033491037. Curr Drug Targets. 2003. PMID: 12699351 Review.

8

Cellular localization and functional characterization of the equilibrative nucleoside transporters of antitumor nucleosides.

Endo Y, Obata T, Murata D, Ito M, Sakamoto K, Fukushima M, Yamasaki Y, Yamada Y, Natsume N, Sasaki T. Endo Y, et al. Among authors: sasaki t. Cancer Sci. 2007 Oct;98(10):1633-7. doi: 10.1111/j.1349-7006.2007.00581.x. Epub 2007 Aug 16. Cancer Sci. 2007. PMID: 17711502 Free PMC article.

9

Synthesis, configurational stability and stereochemical biological evaluations of (S)- and (R)-5-hydroxythalidomides.

Yamamoto T, Shibata N, Sukeguchi D, Takashima M, Nakamura S, Toru T, Matsunaga N, Hara H, Tanaka M, Obata T, Sasaki T. Yamamoto T, et al. Among authors: sasaki t. Bioorg Med Chem Lett. 2009 Jul 15;19(14):3973-6. doi: 10.1016/j.bmcl.2009.02.108. Epub 2009 Mar 3. Bioorg Med Chem Lett. 2009. PMID: 19297157

10

Recent advances in the treatment of peritoneal dissemination of gastrointestinal cancers by nucleoside antimetabolites.

Yonemura Y, Endo Y, Obata T, Sasaki T. Yonemura Y, et al. Among authors: sasaki t. Cancer Sci. 2007 Jan;98(1):11-8. doi: 10.1111/j.1349-7006.2006.00350.x. Cancer Sci. 2007. PMID: 17052255 Free PMC article. Review.

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