Neckers L - Search Results

1

Tumour necrosis factor receptor 1 mediates endoplasmic reticulum stress-induced activation of the MAP kinase JNK.

Yang Q, Kim YS, Lin Y, Lewis J, Neckers L, Liu ZG. Yang Q, et al. Among authors: neckers l. EMBO Rep. 2006 Jun;7(6):622-7. doi: 10.1038/sj.embor.7400687. Epub 2006 May 5. EMBO Rep. 2006. PMID: 16680093 Free PMC article.

2

Disruption of hsp90 function results in degradation of the death domain kinase, receptor-interacting protein (RIP), and blockage of tumor necrosis factor-induced nuclear factor-kappaB activation.

Lewis J, Devin A, Miller A, Lin Y, Rodriguez Y, Neckers L, Liu ZG. Lewis J, et al. Among authors: neckers l. J Biol Chem. 2000 Apr 7;275(14):10519-26. doi: 10.1074/jbc.275.14.10519. J Biol Chem. 2000. PMID: 10744744 Free article.

3

Hypoxia-inducible factor induction by tumour necrosis factor in normoxic cells requires receptor-interacting protein-dependent nuclear factor kappa B activation.

Jung Y, Isaacs JS, Lee S, Trepel J, Liu ZG, Neckers L. Jung Y, et al. Among authors: neckers l. Biochem J. 2003 Mar 15;370(Pt 3):1011-7. doi: 10.1042/BJ20021279. Biochem J. 2003. PMID: 12479793 Free PMC article.

4

Sensitivity of epidermal growth factor receptor and ErbB2 exon 20 insertion mutants to Hsp90 inhibition.

Xu W, Soga S, Beebe K, Lee MJ, Kim YS, Trepel J, Neckers L. Xu W, et al. Among authors: neckers l. Br J Cancer. 2007 Sep 17;97(6):741-4. doi: 10.1038/sj.bjc.6603950. Epub 2007 Aug 21. Br J Cancer. 2007. PMID: 17712310 Free PMC article.

5

Just say NO: nitric oxide regulation of Hsp90.

Scroggins BT, Neckers L. Scroggins BT, et al. Among authors: neckers l. EMBO Rep. 2009 Oct;10(10):1093-4. doi: 10.1038/embor.2009.212. Epub 2009 Sep 18. EMBO Rep. 2009. PMID: 19763143 Free PMC article. No abstract available.

6

Update on Hsp90 inhibitors in clinical trial.

Kim YS, Alarcon SV, Lee S, Lee MJ, Giaccone G, Neckers L, Trepel JB. Kim YS, et al. Among authors: neckers l. Curr Top Med Chem. 2009;9(15):1479-92. doi: 10.2174/156802609789895728. Curr Top Med Chem. 2009. PMID: 19860730 Free PMC article. Review.

7

Tumor-intrinsic and tumor-extrinsic factors impacting hsp90- targeted therapy.

Alarcon SV, Mollapour M, Lee MJ, Tsutsumi S, Lee S, Kim YS, Prince T, Apolo AB, Giaccone G, Xu W, Neckers LM, Trepel JB. Alarcon SV, et al. Among authors: neckers lm. Curr Mol Med. 2012 Nov 1;12(9):1125-41. doi: 10.2174/156652412803306729. Curr Mol Med. 2012. PMID: 22804236 Free PMC article. Review.

8

Possible role for serine/threonine phosphorylation in the regulation of the heteroprotein complex between the hsp90 stress protein and the pp60v-src tyrosine kinase.

Mimnaugh EG, Worland PJ, Whitesell L, Neckers LM. Mimnaugh EG, et al. Among authors: neckers lm. J Biol Chem. 1995 Dec 1;270(48):28654-9. doi: 10.1074/jbc.270.48.28654. J Biol Chem. 1995. PMID: 7499384 Free article.

9

Sensitive and simple bioassay for human tumour necrosis factor-alpha.

Blagosklonny MV, Neckers LM. Blagosklonny MV, et al. Among authors: neckers lm. Eur Cytokine Netw. 1993 Jul-Aug;4(4):279-83. Eur Cytokine Netw. 1993. PMID: 8268418

10

Polyubiquitination and proteasomal degradation of the p185c-erbB-2 receptor protein-tyrosine kinase induced by geldanamycin.

Mimnaugh EG, Chavany C, Neckers L. Mimnaugh EG, et al. Among authors: neckers l. J Biol Chem. 1996 Sep 13;271(37):22796-801. doi: 10.1074/jbc.271.37.22796. J Biol Chem. 1996. PMID: 8798456 Free article.

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