Smart RC - Search Results

1

TAK1 is a master regulator of epidermal homeostasis involving skin inflammation and apoptosis.

Omori E, Matsumoto K, Sanjo H, Sato S, Akira S, Smart RC, Ninomiya-Tsuji J. Omori E, et al. Among authors: smart rc. J Biol Chem. 2006 Jul 14;281(28):19610-7. doi: 10.1074/jbc.M603384200. Epub 2006 May 4. J Biol Chem. 2006. PMID: 16675448 Free PMC article.

2

CCAAT/enhancer binding protein-beta is a mediator of keratinocyte survival and skin tumorigenesis involving oncogenic Ras signaling.

Zhu S, Yoon K, Sterneck E, Johnson PF, Smart RC. Zhu S, et al. Among authors: smart rc. Proc Natl Acad Sci U S A. 2002 Jan 8;99(1):207-12. doi: 10.1073/pnas.012437299. Epub 2001 Dec 26. Proc Natl Acad Sci U S A. 2002. PMID: 11756662 Free PMC article.

3

Deficiency of either cyclooxygenase (COX)-1 or COX-2 alters epidermal differentiation and reduces mouse skin tumorigenesis.

Tiano HF, Loftin CD, Akunda J, Lee CA, Spalding J, Sessoms A, Dunson DB, Rogan EG, Morham SG, Smart RC, Langenbach R. Tiano HF, et al. Among authors: smart rc. Cancer Res. 2002 Jun 15;62(12):3395-401. Cancer Res. 2002. PMID: 12067981

4

Lithium stabilizes the CCAAT/enhancer-binding protein alpha (C/EBPalpha) through a glycogen synthase kinase 3 (GSK3)-independent pathway involving direct inhibition of proteasomal activity.

Shim M, Smart RC. Shim M, et al. Among authors: smart rc. J Biol Chem. 2003 May 30;278(22):19674-81. doi: 10.1074/jbc.M301356200. Epub 2003 Mar 30. J Biol Chem. 2003. PMID: 12668682 Free article.

5

Conditional ablation of C/EBP beta demonstrates its keratinocyte-specific requirement for cell survival and mouse skin tumorigenesis.

Sterneck E, Zhu S, Ramirez A, Jorcano JL, Smart RC. Sterneck E, et al. Among authors: smart rc. Oncogene. 2006 Feb 23;25(8):1272-1276. doi: 10.1038/sj.onc.1209144. Oncogene. 2006. PMID: 16205634 Free PMC article.

6

Decreased survival of C/EBP beta-deficient keratinocytes is due to aberrant regulation of p53 levels and function.

Yoon K, Zhu S, Ewing SJ, Smart RC. Yoon K, et al. Among authors: smart rc. Oncogene. 2007 Jan 18;26(3):360-7. doi: 10.1038/sj.onc.1209797. Epub 2006 Jul 10. Oncogene. 2007. PMID: 16832342

7

Genetic ablation of CCAAT/enhancer binding protein alpha in epidermis reveals its role in suppression of epithelial tumorigenesis.

Loomis KD, Zhu S, Yoon K, Johnson PF, Smart RC. Loomis KD, et al. Among authors: smart rc. Cancer Res. 2007 Jul 15;67(14):6768-76. doi: 10.1158/0008-5472.CAN-07-0139. Cancer Res. 2007. PMID: 17638888 Free PMC article.

8

Ablation of TAK1 upregulates reactive oxygen species and selectively kills tumor cells.

Omori E, Matsumoto K, Zhu S, Smart RC, Ninomiya-Tsuji J. Omori E, et al. Among authors: smart rc. Cancer Res. 2010 Nov 1;70(21):8417-25. doi: 10.1158/0008-5472.CAN-10-1227. Epub 2010 Oct 19. Cancer Res. 2010. PMID: 20959492 Free PMC article.

9

Epidermal protein kinase C-beta 2 is highly sensitive to downregulation and is exclusively expressed in Langerhans cells: downregulation is associated with attenuated contact hypersensitivity.

Goodell AL, Oh HS, Meyer SA, Smart RC. Goodell AL, et al. Among authors: smart rc. J Invest Dermatol. 1996 Sep;107(3):354-9. doi: 10.1111/1523-1747.ep12363325. J Invest Dermatol. 1996. PMID: 8751970 Free article.

10

An estrogen receptor pathway regulates the telogen-anagen hair follicle transition and influences epidermal cell proliferation.

Oh HS, Smart RC. Oh HS, et al. Among authors: smart rc. Proc Natl Acad Sci U S A. 1996 Oct 29;93(22):12525-30. doi: 10.1073/pnas.93.22.12525. Proc Natl Acad Sci U S A. 1996. PMID: 8901615 Free PMC article.

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