Akira S - Search Results

1

TAK1 is a master regulator of epidermal homeostasis involving skin inflammation and apoptosis.

Omori E, Matsumoto K, Sanjo H, Sato S, Akira S, Smart RC, Ninomiya-Tsuji J. Omori E, et al. Among authors: akira s. J Biol Chem. 2006 Jul 14;281(28):19610-7. doi: 10.1074/jbc.M603384200. Epub 2006 May 4. J Biol Chem. 2006. PMID: 16675448 Free PMC article.

2

TAK1 is a component of the Epstein-Barr virus LMP1 complex and is essential for activation of JNK but not of NF-kappaB.

Uemura N, Kajino T, Sanjo H, Sato S, Akira S, Matsumoto K, Ninomiya-Tsuji J. Uemura N, et al. Among authors: akira s. J Biol Chem. 2006 Mar 24;281(12):7863-72. doi: 10.1074/jbc.M509834200. Epub 2006 Jan 30. J Biol Chem. 2006. PMID: 16446357 Free PMC article.

3

Osmotic stress activates the TAK1-JNK pathway while blocking TAK1-mediated NF-kappaB activation: TAO2 regulates TAK1 pathways.

Huangfu WC, Omori E, Akira S, Matsumoto K, Ninomiya-Tsuji J. Huangfu WC, et al. Among authors: akira s. J Biol Chem. 2006 Sep 29;281(39):28802-10. doi: 10.1074/jbc.M603627200. Epub 2006 Aug 7. J Biol Chem. 2006. PMID: 16893890 Free PMC article.

4

Enterocyte-derived TAK1 signaling prevents epithelium apoptosis and the development of ileitis and colitis.

Kajino-Sakamoto R, Inagaki M, Lippert E, Akira S, Robine S, Matsumoto K, Jobin C, Ninomiya-Tsuji J. Kajino-Sakamoto R, et al. Among authors: akira s. J Immunol. 2008 Jul 15;181(2):1143-52. doi: 10.4049/jimmunol.181.2.1143. J Immunol. 2008. PMID: 18606667 Free PMC article.

5

Transforming growth factor beta-activated kinase 1 (TAK1) kinase adaptor, TAK1-binding protein 2, plays dual roles in TAK1 signaling by recruiting both an activator and an inhibitor of TAK1 kinase in tumor necrosis factor signaling pathway.

Broglie P, Matsumoto K, Akira S, Brautigan DL, Ninomiya-Tsuji J. Broglie P, et al. Among authors: akira s. J Biol Chem. 2010 Jan 22;285(4):2333-9. doi: 10.1074/jbc.M109.090522. Epub 2009 Dec 2. J Biol Chem. 2010. PMID: 19955178 Free PMC article.

6

TAB2 is essential for prevention of apoptosis in fetal liver but not for interleukin-1 signaling.

Sanjo H, Takeda K, Tsujimura T, Ninomiya-Tsuji J, Matsumoto K, Akira S. Sanjo H, et al. Among authors: akira s. Mol Cell Biol. 2003 Feb;23(4):1231-8. doi: 10.1128/MCB.23.4.1231-1238.2003. Mol Cell Biol. 2003. PMID: 12556483 Free PMC article.

7

TAK1-binding protein 2 facilitates ubiquitination of TRAF6 and assembly of TRAF6 with IKK in the IL-1 signaling pathway.

Kishida S, Sanjo H, Akira S, Matsumoto K, Ninomiya-Tsuji J. Kishida S, et al. Among authors: akira s. Genes Cells. 2005 May;10(5):447-54. doi: 10.1111/j.1365-2443.2005.00852.x. Genes Cells. 2005. PMID: 15836773 Free PMC article.

8

Essential function for the kinase TAK1 in innate and adaptive immune responses.

Sato S, Sanjo H, Takeda K, Ninomiya-Tsuji J, Yamamoto M, Kawai T, Matsumoto K, Takeuchi O, Akira S. Sato S, et al. Among authors: akira s. Nat Immunol. 2005 Nov;6(11):1087-95. doi: 10.1038/ni1255. Epub 2005 Sep 25. Nat Immunol. 2005. PMID: 16186825

9

TLR8-mediated NF-kappaB and JNK activation are TAK1-independent and MEKK3-dependent.

Qin J, Yao J, Cui G, Xiao H, Kim TW, Fraczek J, Wightman P, Sato S, Akira S, Puel A, Casanova JL, Su B, Li X. Qin J, et al. Among authors: akira s. J Biol Chem. 2006 Jul 28;281(30):21013-21021. doi: 10.1074/jbc.M512908200. Epub 2006 May 31. J Biol Chem. 2006. PMID: 16737960 Free article.

10

TAK1 is indispensable for development of T cells and prevention of colitis by the generation of regulatory T cells.

Sato S, Sanjo H, Tsujimura T, Ninomiya-Tsuji J, Yamamoto M, Kawai T, Takeuchi O, Akira S. Sato S, et al. Among authors: akira s. Int Immunol. 2006 Oct;18(10):1405-11. doi: 10.1093/intimm/dxl082. Epub 2006 Aug 28. Int Immunol. 2006. PMID: 16940043

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