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Page 1
The p110beta isoform of phosphoinositide 3-kinase signals downstream of G protein-coupled receptors and is functionally redundant with p110gamma.
Guillermet-Guibert J, Bjorklof K, Salpekar A, Gonella C, Ramadani F, Bilancio A, Meek S, Smith AJ, Okkenhaug K, Vanhaesebroeck B. Guillermet-Guibert J, et al. Among authors: smith aj. Proc Natl Acad Sci U S A. 2008 Jun 17;105(24):8292-7. doi: 10.1073/pnas.0707761105. Epub 2008 Jun 10. Proc Natl Acad Sci U S A. 2008. PMID: 18544649 Free PMC article.
Dominant role of the p110beta isoform of PI3K over p110alpha in energy homeostasis regulation by POMC and AgRP neurons.
Al-Qassab H, Smith MA, Irvine EE, Guillermet-Guibert J, Claret M, Choudhury AI, Selman C, Piipari K, Clements M, Lingard S, Chandarana K, Bell JD, Barsh GS, Smith AJ, Batterham RL, Ashford ML, Vanhaesebroeck B, Withers DJ. Al-Qassab H, et al. Among authors: smith aj, smith ma. Cell Metab. 2009 Nov;10(5):343-54. doi: 10.1016/j.cmet.2009.09.008. Cell Metab. 2009. PMID: 19883613 Free PMC article.
Control of axonal growth and regeneration of sensory neurons by the p110delta PI 3-kinase.
Eickholt BJ, Ahmed AI, Davies M, Papakonstanti EA, Pearce W, Starkey ML, Bilancio A, Need AC, Smith AJ, Hall SM, Hamers FP, Giese KP, Bradbury EJ, Vanhaesebroeck B. Eickholt BJ, et al. Among authors: smith aj. PLoS One. 2007 Sep 11;2(9):e869. doi: 10.1371/journal.pone.0000869. PLoS One. 2007. PMID: 17846664 Free PMC article.
An interspecies analysis reveals a key role for unmethylated CpG dinucleotides in vertebrate Polycomb complex recruitment.
Lynch MD, Smith AJ, De Gobbi M, Flenley M, Hughes JR, Vernimmen D, Ayyub H, Sharpe JA, Sloane-Stanley JA, Sutherland L, Meek S, Burdon T, Gibbons RJ, Garrick D, Higgs DR. Lynch MD, et al. Among authors: smith aj. EMBO J. 2012 Jan 18;31(2):317-29. doi: 10.1038/emboj.2011.399. Epub 2011 Nov 4. EMBO J. 2012. PMID: 22056776 Free PMC article.
Genetic dissection of the α-globin super-enhancer in vivo.
Hay D, Hughes JR, Babbs C, Davies JOJ, Graham BJ, Hanssen L, Kassouf MT, Marieke Oudelaar AM, Sharpe JA, Suciu MC, Telenius J, Williams R, Rode C, Li PS, Pennacchio LA, Sloane-Stanley JA, Ayyub H, Butler S, Sauka-Spengler T, Gibbons RJ, Smith AJH, Wood WG, Higgs DR. Hay D, et al. Nat Genet. 2016 Aug;48(8):895-903. doi: 10.1038/ng.3605. Epub 2016 Jul 4. Nat Genet. 2016. PMID: 27376235 Free PMC article.
Triacylglycerol mobilization underpins mitochondrial stress recovery.
Baker ZN, Zhu Y, Guerra RM, Smith AJ, Arra A, Serrano LR, Overmyer KA, Mukherji S, Craig EA, Coon JJ, Pagliarini DJ. Baker ZN, et al. Among authors: smith aj. Nat Cell Biol. 2025 Jan 8. doi: 10.1038/s41556-024-01586-6. Online ahead of print. Nat Cell Biol. 2025. PMID: 39779944
2,173 results