Toney MD - Search Results

1

Slow-binding human serine racemase inhibitors from high-throughput screening of combinatorial libraries.

Dixon SM, Li P, Liu R, Wolosker H, Lam KS, Kurth MJ, Toney MD. Dixon SM, et al. Among authors: toney md. J Med Chem. 2006 Apr 20;49(8):2388-97. doi: 10.1021/jm050701c. J Med Chem. 2006. PMID: 16610782

2

Aminodeoxychorismate synthase inhibitors from one-bead one-compound combinatorial libraries: "staged" inhibitor design.

Dixon S, Ziebart KT, He Z, Jeddeloh M, Yoo CL, Wang X, Lehman A, Lam KS, Toney MD, Kurth MJ. Dixon S, et al. Among authors: toney md. J Med Chem. 2006 Dec 14;49(25):7413-26. doi: 10.1021/jm0609869. J Med Chem. 2006. PMID: 17149871

3

Targeting multiple chorismate-utilizing enzymes with a single inhibitor: validation of a three-stage design.

Ziebart KT, Dixon SM, Avila B, El-Badri MH, Guggenheim KG, Kurth MJ, Toney MD. Ziebart KT, et al. Among authors: toney md. J Med Chem. 2010 May 13;53(9):3718-29. doi: 10.1021/jm100158v. J Med Chem. 2010. PMID: 20359225

4

Orthogonally protected thiazole and isoxazole diamino acids: an efficient synthetic route.

Butler JD, Coffman KC, Ziebart KT, Toney MD, Kurth MJ. Butler JD, et al. Among authors: toney md. Chemistry. 2010 Aug 9;16(30):9002-5. doi: 10.1002/chem.201001492. Chemistry. 2010. PMID: 20623732 No abstract available.

5

Serine racemase modulates intracellular D-serine levels through an alpha,beta-elimination activity.

Foltyn VN, Bendikov I, De Miranda J, Panizzutti R, Dumin E, Shleper M, Li P, Toney MD, Kartvelishvily E, Wolosker H. Foltyn VN, et al. Among authors: toney md. J Biol Chem. 2005 Jan 21;280(3):1754-63. doi: 10.1074/jbc.M405726200. Epub 2004 Nov 9. J Biol Chem. 2005. PMID: 15536068 Free article.

6

Chemoenzymatic synthesis of 1-deaza-pyridoxal 5'-phosphate.

Griswold WR, Toney MD. Griswold WR, et al. Among authors: toney md. Bioorg Med Chem Lett. 2010 Feb 15;20(4):1352-4. doi: 10.1016/j.bmcl.2010.01.002. Epub 2010 Jan 7. Bioorg Med Chem Lett. 2010. PMID: 20097067 Free PMC article.

7

Aminophosphonate inhibitors of dialkylglycine decarboxylase: structural basis for slow binding inhibition.

Liu W, Rogers CJ, Fisher AJ, Toney MD. Liu W, et al. Among authors: toney md. Biochemistry. 2002 Oct 15;41(41):12320-8. doi: 10.1021/bi026318g. Biochemistry. 2002. PMID: 12369820

8

Rapid photodynamics of vitamin B6 coenzyme pyridoxal 5'-phosphate and its Schiff bases in solution.

Hill MP, Carroll EC, Toney MD, Larsen DS. Hill MP, et al. Among authors: toney md. J Phys Chem B. 2008 May 8;112(18):5867-73. doi: 10.1021/jp7117345. Epub 2008 Apr 17. J Phys Chem B. 2008. PMID: 18416573

9

A continuous-flow system for high-precision kinetics using small volumes.

Zhou X, Medhekar R, Toney MD. Zhou X, et al. Among authors: toney md. Anal Chem. 2003 Aug 1;75(15):3681-7. doi: 10.1021/ac034068j. Anal Chem. 2003. PMID: 14572030

10

Cloning and characterization of a phosphopantetheinyl transferase from Streptomyces verticillus ATCC15003, the producer of the hybrid peptide-polyketide antitumor drug bleomycin.

Sánchez C, Du L, Edwards DJ, Toney MD, Shen B. Sánchez C, et al. Among authors: toney md. Chem Biol. 2001 Jul;8(7):725-38. doi: 10.1016/s1074-5521(01)00047-3. Chem Biol. 2001. PMID: 11451672

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