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Page 1
Heterocyclic and phenyl double-bond-locked combretastatin analogues possessing potent apoptosis-inducing activity in HL60 and in MDR cell lines.
Simoni D, Grisolia G, Giannini G, Roberti M, Rondanin R, Piccagli L, Baruchello R, Rossi M, Romagnoli R, Invidiata FP, Grimaudo S, Jung MK, Hamel E, Gebbia N, Crosta L, Abbadessa V, Di Cristina A, Dusonchet L, Meli M, Tolomeo M. Simoni D, et al. J Med Chem. 2005 Feb 10;48(3):723-36. doi: 10.1021/jm049622b. J Med Chem. 2005. PMID: 15689156
Synthesis and pharmacology of 6-substituted benztropines: discovery of novel dopamine uptake inhibitors possessing low binding affinity to the dopamine transporter.
Simoni D, Rossi M, Bertolasi V, Roberti M, Pizzirani D, Rondanin R, Baruchello R, Invidiata FP, Tolomeo M, Grimaudo S, Merighi S, Varani K, Gessi S, Borea PA, Marino S, Cavallini S, Bianchi C, Siniscalchi A. Simoni D, et al. J Med Chem. 2005 May 5;48(9):3337-43. doi: 10.1021/jm0490235. J Med Chem. 2005. PMID: 15857139
Studies on the apoptotic activity of natural and synthetic retinoids: discovery of a new class of synthetic terphenyls that potently support cell growth and inhibit apoptosis in neuronal and HL-60 cells.
Simoni D, Giannini G, Roberti M, Rondanin R, Baruchello R, Rossi M, Grisolia G, Invidiata FP, Aiello S, Marino S, Cavallini S, Siniscalchi A, Gebbia N, Crosta L, Grimaudo S, Abbadessa V, Di Cristina A, Tolomeo M. Simoni D, et al. J Med Chem. 2005 Jun 30;48(13):4293-9. doi: 10.1021/jm049080y. J Med Chem. 2005. PMID: 15974583
Design, synthesis, and biological evaluation of novel aminobisphosphonates possessing an in vivo antitumor activity through a gammadelta-T lymphocytes-mediated activation mechanism.
Simoni D, Gebbia N, Invidiata FP, Eleopra M, Marchetti P, Rondanin R, Baruchello R, Provera S, Marchioro C, Tolomeo M, Marinelli L, Limongelli V, Novellino E, Kwaasi A, Dunford J, Buccheri S, Caccamo N, Dieli F. Simoni D, et al. J Med Chem. 2008 Nov 13;51(21):6800-7. doi: 10.1021/jm801003y. Epub 2008 Oct 21. J Med Chem. 2008. PMID: 18937434
119 results