Nur-e-Alam M - Search Results

1

Novel GC-rich DNA-binding compound produced by a genetically engineered mutant of the mithramycin producer Streptomyces argillaceus exhibits improved transcriptional repressor activity: implications for cancer therapy.

Albertini V, Jain A, Vignati S, Napoli S, Rinaldi A, Kwee I, Nur-e-Alam M, Bergant J, Bertoni F, Carbone GM, Rohr J, Catapano CV. Albertini V, et al. Nucleic Acids Res. 2006 Mar 29;34(6):1721-34. doi: 10.1093/nar/gkl063. Print 2006. Nucleic Acids Res. 2006. PMID: 16571899 Free PMC article.

2

Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesis.

Remsing LL, González AM, Nur-e-Alam M, Fernández-Lozano MJ, Braña AF, Rix U, Oliveira MA, Méndez C, Salas JA, Rohr J. Remsing LL, et al. J Am Chem Soc. 2003 May 14;125(19):5745-53. doi: 10.1021/ja034162h. J Am Chem Soc. 2003. PMID: 12733914 Free PMC article.

3

Biosynthesis of the antitumor chromomycin A3 in Streptomyces griseus: analysis of the gene cluster and rational design of novel chromomycin analogs.

Menéndez N, Nur-e-Alam M, Braña AF, Rohr J, Salas JA, Méndez C. Menéndez N, et al. Chem Biol. 2004 Jan;11(1):21-32. doi: 10.1016/j.chembiol.2003.12.011. Chem Biol. 2004. PMID: 15112992 Free article.

4

Deoxysugar transfer during chromomycin A3 biosynthesis in Streptomyces griseus subsp. griseus: new derivatives with antitumor activity.

Menéndez N, Nur-e-Alam M, Fischer C, Braña AF, Salas JA, Rohr J, Méndez C. Menéndez N, et al. Appl Environ Microbiol. 2006 Jan;72(1):167-77. doi: 10.1128/AEM.72.1.167-177.2006. Appl Environ Microbiol. 2006. PMID: 16391039 Free PMC article.

5

Elucidation of the glycosylation sequence of mithramycin biosynthesis: isolation of 3A-deolivosylpremithramycin B and its conversion to premithramycin B by glycosyltransferase MtmGII.

Nur-e-Alam M, Méndez C, Salas JA, Rohr J. Nur-e-Alam M, et al. Chembiochem. 2005 Apr;6(4):632-6. doi: 10.1002/cbic.200400309. Chembiochem. 2005. PMID: 15712316 No abstract available.

6

Characterization of kinetics and products of the Baeyer-Villiger oxygenase MtmOIV, the key enzyme of the biosynthetic pathway toward the natural product anticancer drug mithramycin from Streptomyces argillaceus.

Gibson M, Nur-e-alam M, Lipata F, Oliveira MA, Rohr J. Gibson M, et al. J Am Chem Soc. 2005 Dec 21;127(50):17594-5. doi: 10.1021/ja055750t. J Am Chem Soc. 2005. PMID: 16351075

7

Investigation on Semecarpus Lehyam--a Siddha medicine for breast cancer.

Sowmyalakshmi S, Nur-E-Alam M, Akbarsha MA, Thirugnanam S, Rohr J, Chendil D. Sowmyalakshmi S, et al. Planta. 2005 Apr;220(6):910-8. doi: 10.1007/s00425-004-1405-4. Epub 2004 Oct 28. Planta. 2005. PMID: 15517350

8

Identification of the function of gene lndM2 encoding a bifunctional oxygenase-reductase involved in the biosynthesis of the antitumor antibiotic landomycin E by Streptomyces globisporus 1912 supports the originally assigned structure for landomycinone.

Zhu L, Ostash B, Rix U, Nur-E-Alam M, Mayers A, Luzhetskyy A, Mendez C, Salas JA, Bechthold A, Fedorenko V, Rohr J. Zhu L, et al. J Org Chem. 2005 Jan 21;70(2):631-8. doi: 10.1021/jo0483623. J Org Chem. 2005. PMID: 15651811 Free PMC article.

9

Tailoring modification of deoxysugars during biosynthesis of the antitumour drug chromomycin A by Streptomyces griseus ssp. griseus.

Menéndez N, Nur-E-Alam M, Braña AF, Rohr J, Salas JA, Méndez C. Menéndez N, et al. Mol Microbiol. 2004 Aug;53(3):903-15. doi: 10.1111/j.1365-2958.2004.04166.x. Mol Microbiol. 2004. PMID: 15255901 Free article.

10

Insights in the glycosylation steps during biosynthesis of the antitumor anthracycline cosmomycin: characterization of two glycosyltransferase genes.

Garrido LM, Lombó F, Baig I, Nur-E-Alam M, Furlan RL, Borda CC, Braña A, Méndez C, Salas JA, Rohr J, Padilla G. Garrido LM, et al. Appl Microbiol Biotechnol. 2006 Nov;73(1):122-31. doi: 10.1007/s00253-006-0453-z. Epub 2006 Jun 30. Appl Microbiol Biotechnol. 2006. PMID: 16810496 Free PMC article.

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