Feldmann M - Search Results

1

Adenoviral gene transfer into osteoarthritis synovial cells using the endogenous inhibitor IkappaBalpha reveals that most, but not all, inflammatory and destructive mediators are NFkappaB dependent.

Amos N, Lauder S, Evans A, Feldmann M, Bondeson J. Amos N, et al. Among authors: feldmann m. Rheumatology (Oxford). 2006 Oct;45(10):1201-9. doi: 10.1093/rheumatology/kel078. Epub 2006 Mar 29. Rheumatology (Oxford). 2006. PMID: 16571608

2

Effective adenoviral transfer of IkappaBalpha into human fibroblasts and chondrosarcoma cells reveals that the induction of matrix metalloproteinases and proinflammatory cytokines is nuclear factor-kappaB dependent.

Bondeson J, Brennan F, Foxwell B, Feldmann M. Bondeson J, et al. Among authors: feldmann m. J Rheumatol. 2000 Sep;27(9):2078-89. J Rheumatol. 2000. PMID: 10990217

3

Adenoviral gene transfer of the endogenous inhibitor IkappaBalpha into human osteoarthritis synovial fibroblasts demonstrates that several matrix metalloproteinases and aggrecanases are nuclear factor-kappaB-dependent.

Bondeson J, Lauder S, Wainwright S, Amos N, Evans A, Hughes C, Feldmann M, Caterson B. Bondeson J, et al. Among authors: feldmann m. J Rheumatol. 2007 Mar;34(3):523-33. Epub 2007 Jan 15. J Rheumatol. 2007. PMID: 17295438

4

Efficient adenoviral infection with IkappaB alpha reveals that macrophage tumor necrosis factor alpha production in rheumatoid arthritis is NF-kappaB dependent.

Foxwell B, Browne K, Bondeson J, Clarke C, de Martin R, Brennan F, Feldmann M. Foxwell B, et al. Among authors: feldmann m. Proc Natl Acad Sci U S A. 1998 Jul 7;95(14):8211-5. doi: 10.1073/pnas.95.14.8211. Proc Natl Acad Sci U S A. 1998. PMID: 9653166 Free PMC article.

5

Selective regulation of cytokine induction by adenoviral gene transfer of IkappaBalpha into human macrophages: lipopolysaccharide-induced, but not zymosan-induced, proinflammatory cytokines are inhibited, but IL-10 is nuclear factor-kappaB independent.

Bondeson J, Browne KA, Brennan FM, Foxwell BM, Feldmann M. Bondeson J, et al. Among authors: feldmann m. J Immunol. 1999 Mar 1;162(5):2939-45. J Immunol. 1999. PMID: 10072544

6

Defining therapeutic targets by using adenovirus: blocking NF-kappaB inhibits both inflammatory and destructive mechanisms in rheumatoid synovium but spares anti-inflammatory mediators.

Bondeson J, Foxwell B, Brennan F, Feldmann M. Bondeson J, et al. Among authors: feldmann m. Proc Natl Acad Sci U S A. 1999 May 11;96(10):5668-73. doi: 10.1073/pnas.96.10.5668. Proc Natl Acad Sci U S A. 1999. PMID: 10318942 Free PMC article.

7

Adenoviral transgene delivery provides an approach to identifying important molecular processes in inflammation: evidence for heterogenecity in the requirement for NFkappaB in tumour necrosis factor production.

Foxwell BM, Bondeson J, Brennan F, Feldmann M. Foxwell BM, et al. Among authors: feldmann m. Ann Rheum Dis. 2000 Nov;59 Suppl 1(Suppl 1):i54-9. doi: 10.1136/ard.59.suppl_1.i54. Ann Rheum Dis. 2000. PMID: 11053090 Free PMC article. Review.

8

Effective antigen presentation by dendritic cells is NF-kappaB dependent: coordinate regulation of MHC, co-stimulatory molecules and cytokines.

Yoshimura S, Bondeson J, Foxwell BM, Brennan FM, Feldmann M. Yoshimura S, et al. Among authors: feldmann m. Int Immunol. 2001 May;13(5):675-83. doi: 10.1093/intimm/13.5.675. Int Immunol. 2001. PMID: 11312255

9

Role of NFkappaB in antigen presentation and development of regulatory T cells elucidated by treatment of dendritic cells with the proteasome inhibitor PSI.

Yoshimura S, Bondeson J, Brennan FM, Foxwell BM, Feldmann M. Yoshimura S, et al. Among authors: feldmann m. Eur J Immunol. 2001 Jun;31(6):1883-93. doi: 10.1002/1521-4141(200106)31:6<1883::aid-immu1883>3.0.co;2-v. Eur J Immunol. 2001. PMID: 11433385 Free article.

10

Cytokine blockade in rheumatoid arthritis.

Feldmann M, Maini RN, Bondeson J, Taylor P, Foxwell BM, Brennan FM. Feldmann M, et al. Adv Exp Med Biol. 2001;490:119-27. doi: 10.1007/978-1-4615-1243-1_13. Adv Exp Med Biol. 2001. PMID: 11505970 Review.

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