Shiraishi M - Search Results

1

Highly potent and orally active CCR5 antagonists as anti-HIV-1 agents: synthesis and biological activities of 1-benzazocine derivatives containing a sulfoxide moiety.

Seto M, Aikawa K, Miyamoto N, Aramaki Y, Kanzaki N, Takashima K, Kuze Y, Iizawa Y, Baba M, Shiraishi M. Seto M, et al. Among authors: shiraishi m. J Med Chem. 2006 Mar 23;49(6):2037-48. doi: 10.1021/jm0509703. J Med Chem. 2006. PMID: 16539392

2

Orally active CCR5 antagonists as anti-HIV-1 agents. Part 3: Synthesis and biological activities of 1-benzazepine derivatives containing a sulfoxide moiety.

Seto M, Miyamoto N, Aikawa K, Aramaki Y, Kanzaki N, Iizawa Y, Baba M, Shiraishi M. Seto M, et al. Among authors: shiraishi m. Bioorg Med Chem. 2005 Jan 17;13(2):363-86. doi: 10.1016/j.bmc.2004.10.021. Bioorg Med Chem. 2005. PMID: 15598559

3

Synthesis of 1-benzothiepine and 1-benzazepine derivatives as orally active CCR5 antagonists.

Aramaki Y, Seto M, Okawa T, Oda T, Kanzaki N, Shiraishi M. Aramaki Y, et al. Among authors: shiraishi m. Chem Pharm Bull (Tokyo). 2004 Feb;52(2):254-8. doi: 10.1248/cpb.52.254. Chem Pharm Bull (Tokyo). 2004. PMID: 14758013 Free article.

4

Orally active CCR5 antagonists as anti-HIV-1 agents: synthesis and biological activity of 1-benzothiepine 1,1-dioxide and 1-benzazepine derivatives containing a tertiary amine moiety.

Seto M, Aramaki Y, Okawa T, Miyamoto N, Aikawa K, Kanzaki N, Niwa S, Iizawa Y, Baba M, Shiraishi M. Seto M, et al. Among authors: shiraishi m. Chem Pharm Bull (Tokyo). 2004 May;52(5):577-90. doi: 10.1248/cpb.52.577. Chem Pharm Bull (Tokyo). 2004. PMID: 15133211 Free article.

5

Orally active CCR5 antagonists as anti-HIV-1 agents 2: synthesis and biological activities of anilide derivatives containing a pyridine N-oxide moiety.

Seto M, Aramaki Y, Imoto H, Aikawa K, Oda T, Kanzaki N, Iizawa Y, Baba M, Shiraishi M. Seto M, et al. Among authors: shiraishi m. Chem Pharm Bull (Tokyo). 2004 Jul;52(7):818-29. doi: 10.1248/cpb.52.818. Chem Pharm Bull (Tokyo). 2004. PMID: 15256702 Free article.

6

Discovery of novel, potent, and selective small-molecule CCR5 antagonists as anti-HIV-1 agents: synthesis and biological evaluation of anilide derivatives with a quaternary ammonium moiety.

Shiraishi M, Aramaki Y, Seto M, Imoto H, Nishikawa Y, Kanzaki N, Okamoto M, Sawada H, Nishimura O, Baba M, Fujino M. Shiraishi M, et al. J Med Chem. 2000 May 18;43(10):2049-63. doi: 10.1021/jm9906264. J Med Chem. 2000. PMID: 10821717

7

TAK-652 inhibits CCR5-mediated human immunodeficiency virus type 1 infection in vitro and has favorable pharmacokinetics in humans.

Baba M, Takashima K, Miyake H, Kanzaki N, Teshima K, Wang X, Shiraishi M, Iizawa Y. Baba M, et al. Among authors: shiraishi m. Antimicrob Agents Chemother. 2005 Nov;49(11):4584-91. doi: 10.1128/AAC.49.11.4584-4591.2005. Antimicrob Agents Chemother. 2005. PMID: 16251299 Free PMC article. Clinical Trial.

8

Synthesis and biological evaluation of novel selective androgen receptor modulators (SARMs). Part I.

Aikawa K, Miyawaki T, Hitaka T, Imai YN, Hara T, Miyazaki J, Yamaoka M, Kusaka M, Kanzaki N, Tasaka A, Shiraishi M, Yamamoto S. Aikawa K, et al. Among authors: shiraishi m. Bioorg Med Chem. 2015 May 15;23(10):2568-78. doi: 10.1016/j.bmc.2015.03.032. Epub 2015 Mar 19. Bioorg Med Chem. 2015. PMID: 25862209

9

Inhibitory effects of small-molecule CCR5 antagonists on human immunodeficiency virus type 1 envelope-mediated membrane fusion and viral replication.

Takashima K, Miyake H, Furuta RA, Fujisawa JI, Iizawa Y, Kanzaki N, Shiraishi M, Okonogi K, Baba M. Takashima K, et al. Among authors: shiraishi m. Antimicrob Agents Chemother. 2001 Dec;45(12):3538-43. doi: 10.1128/AAC.45.12.3538-3543.2001. Antimicrob Agents Chemother. 2001. PMID: 11709336 Free PMC article.

10

A small-molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity.

Baba M, Nishimura O, Kanzaki N, Okamoto M, Sawada H, Iizawa Y, Shiraishi M, Aramaki Y, Okonogi K, Ogawa Y, Meguro K, Fujino M. Baba M, et al. Among authors: shiraishi m. Proc Natl Acad Sci U S A. 1999 May 11;96(10):5698-703. doi: 10.1073/pnas.96.10.5698. Proc Natl Acad Sci U S A. 1999. PMID: 10318947 Free PMC article.

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