Lim SP - Search Results

1

Structural basis for the activation of flaviviral NS3 proteases from dengue and West Nile virus.

Erbel P, Schiering N, D'Arcy A, Renatus M, Kroemer M, Lim SP, Yin Z, Keller TH, Vasudevan SG, Hommel U. Erbel P, et al. Among authors: lim sp. Nat Struct Mol Biol. 2006 Apr;13(4):372-3. doi: 10.1038/nsmb1073. Epub 2006 Mar 12. Nat Struct Mol Biol. 2006. PMID: 16532006

2

Peptide inhibitors of West Nile NS3 protease: SAR study of tetrapeptide aldehyde inhibitors.

Knox JE, Ma NL, Yin Z, Patel SJ, Wang WL, Chan WL, Ranga Rao KR, Wang G, Ngew X, Patel V, Beer D, Lim SP, Vasudevan SG, Keller TH. Knox JE, et al. Among authors: lim sp. J Med Chem. 2006 Nov 2;49(22):6585-90. doi: 10.1021/jm0607606. J Med Chem. 2006. PMID: 17064076

3

Purification and crystallization of dengue and West Nile virus NS2B-NS3 complexes.

D'Arcy A, Chaillet M, Schiering N, Villard F, Lim SP, Lefeuvre P, Erbel P. D'Arcy A, et al. Among authors: lim sp. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Feb 1;62(Pt 2):157-62. doi: 10.1107/S1744309106001199. Epub 2006 Jan 27. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006. PMID: 16511290 Free PMC article.

4

NMR study of complexes between low molecular mass inhibitors and the West Nile virus NS2B-NS3 protease.

Su XC, Ozawa K, Yagi H, Lim SP, Wen D, Ekonomiuk D, Huang D, Keller TH, Sonntag S, Caflisch A, Vasudevan SG, Otting G. Su XC, et al. Among authors: lim sp. FEBS J. 2009 Aug;276(15):4244-55. doi: 10.1111/j.1742-4658.2009.07132.x. Epub 2009 Jul 3. FEBS J. 2009. PMID: 19583774 Free article.

5

NMR analysis of the dynamic exchange of the NS2B cofactor between open and closed conformations of the West Nile virus NS2B-NS3 protease.

Su XC, Ozawa K, Qi R, Vasudevan SG, Lim SP, Otting G. Su XC, et al. Among authors: lim sp. PLoS Negl Trop Dis. 2009 Dec 8;3(12):e561. doi: 10.1371/journal.pntd.0000561. PLoS Negl Trop Dis. 2009. PMID: 19997625 Free PMC article.

6

Dengue protease activity: the structural integrity and interaction of NS2B with NS3 protease and its potential as a drug target.

Phong WY, Moreland NJ, Lim SP, Wen D, Paradkar PN, Vasudevan SG. Phong WY, et al. Among authors: lim sp. Biosci Rep. 2011 Oct;31(5):399-409. doi: 10.1042/BSR20100142. Biosci Rep. 2011. PMID: 21329491

7

The Dengue Virus Replication Complex: From RNA Replication to Protein-Protein Interactions to Evasion of Innate Immunity.

Lescar J, Soh S, Lee LT, Vasudevan SG, Kang C, Lim SP. Lescar J, et al. Among authors: lim sp. Adv Exp Med Biol. 2018;1062:115-129. doi: 10.1007/978-981-10-8727-1_9. Adv Exp Med Biol. 2018. PMID: 29845529 Review.

8

Functional profiling of recombinant NS3 proteases from all four serotypes of dengue virus using tetrapeptide and octapeptide substrate libraries.

Li J, Lim SP, Beer D, Patel V, Wen D, Tumanut C, Tully DC, Williams JA, Jiricek J, Priestle JP, Harris JL, Vasudevan SG. Li J, et al. Among authors: lim sp. J Biol Chem. 2005 Aug 5;280(31):28766-74. doi: 10.1074/jbc.M500588200. Epub 2005 Jun 1. J Biol Chem. 2005. PMID: 15932883 Free article.

9

Peptide inhibitors of Dengue virus NS3 protease. Part 1: Warhead.

Yin Z, Patel SJ, Wang WL, Wang G, Chan WL, Rao KR, Alam J, Jeyaraj DA, Ngew X, Patel V, Beer D, Lim SP, Vasudevan SG, Keller TH. Yin Z, et al. Among authors: lim sp. Bioorg Med Chem Lett. 2006 Jan 1;16(1):36-9. doi: 10.1016/j.bmcl.2005.09.062. Epub 2005 Oct 21. Bioorg Med Chem Lett. 2006. PMID: 16246553

10

Peptide inhibitors of dengue virus NS3 protease. Part 2: SAR study of tetrapeptide aldehyde inhibitors.

Yin Z, Patel SJ, Wang WL, Chan WL, Ranga Rao KR, Wang G, Ngew X, Patel V, Beer D, Knox JE, Ma NL, Ehrhardt C, Lim SP, Vasudevan SG, Keller TH. Yin Z, et al. Among authors: lim sp. Bioorg Med Chem Lett. 2006 Jan 1;16(1):40-3. doi: 10.1016/j.bmcl.2005.09.049. Epub 2005 Oct 21. Bioorg Med Chem Lett. 2006. PMID: 16246563

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