Griffiths JR - Search Results

1

Tumour overexpression of inducible nitric oxide synthase (iNOS) increases angiogenesis and may modulate the anti-tumour effects of the vascular disrupting agent ZD6126.

Cullis ER, Kalber TL, Ashton SE, Cartwright JE, Griffiths JR, Ryan AJ, Robinson SP. Cullis ER, et al. Among authors: griffiths jr. Microvasc Res. 2006 Mar;71(2):76-84. doi: 10.1016/j.mvr.2006.01.004. Epub 2006 Mar 10. Microvasc Res. 2006. PMID: 16530791

2

Effects of overexpression of dimethylarginine dimethylaminohydrolase on tumor angiogenesis assessed by susceptibility magnetic resonance imaging.

Kostourou V, Robinson SP, Whitley GS, Griffiths JR. Kostourou V, et al. Among authors: griffiths jr. Cancer Res. 2003 Aug 15;63(16):4960-6. Cancer Res. 2003. PMID: 12941821

3

Overexpression of dimethylarginine dimethylaminohydrolase enhances tumor hypoxia: an insight into the relationship of hypoxia and angiogenesis in vivo.

Kostourou V, Troy H, Murray JF, Cullis ER, Whitley GS, Griffiths JR, Robinson SP. Kostourou V, et al. Among authors: griffiths jr. Neoplasia. 2004 Jul-Aug;6(4):401-11. doi: 10.1593/neo.04109. Neoplasia. 2004. PMID: 15256062 Free PMC article.

4

Acute tumor response to ZD6126 assessed by intrinsic susceptibility magnetic resonance imaging.

Robinson SP, Kalber TL, Howe FA, McIntyre DJ, Griffiths JR, Blakey DC, Whittaker L, Ryan AJ, Waterton JC. Robinson SP, et al. Among authors: griffiths jr. Neoplasia. 2005 May;7(5):466-74. doi: 10.1593/neo.04622. Neoplasia. 2005. PMID: 15967099 Free PMC article.

5

The response of RIF-1 fibrosarcomas to the vascular-disrupting agent ZD6126 assessed by in vivo and ex vivo 1H magnetic resonance spectroscopy.

Madhu B, Waterton JC, Griffiths JR, Ryan AJ, Robinson SP. Madhu B, et al. Among authors: griffiths jr. Neoplasia. 2006 Jul;8(7):560-7. doi: 10.1593/neo.06319. Neoplasia. 2006. PMID: 16867218 Free PMC article.

6

Susceptibility contrast magnetic resonance imaging determination of fractional tumor blood volume: a noninvasive imaging biomarker of response to the vascular disrupting agent ZD6126.

Robinson SP, Howe FA, Griffiths JR, Ryan AJ, Waterton JC. Robinson SP, et al. Among authors: griffiths jr. Int J Radiat Oncol Biol Phys. 2007 Nov 1;69(3):872-9. doi: 10.1016/j.ijrobp.2007.06.061. Int J Radiat Oncol Biol Phys. 2007. PMID: 17889267

7

Tumour dose response to the antivascular agent ZD6126 assessed by magnetic resonance imaging.

Robinson SP, McIntyre DJ, Checkley D, Tessier JJ, Howe FA, Griffiths JR, Ashton SE, Ryan AJ, Blakey DC, Waterton JC. Robinson SP, et al. Among authors: griffiths jr. Br J Cancer. 2003 May 19;88(10):1592-7. doi: 10.1038/sj.bjc.6600926. Br J Cancer. 2003. PMID: 12771928 Free PMC article.

8

Single dose of the antivascular agent, ZD6126 (N-acetylcolchinol-O-phosphate), reduces perfusion for at least 96 hours in the GH3 prolactinoma rat tumor model.

McIntyre DJ, Robinson SP, Howe FA, Griffiths JR, Ryan AJ, Blakey DC, Peers IS, Waterton JC. McIntyre DJ, et al. Among authors: griffiths jr. Neoplasia. 2004 Mar-Apr;6(2):150-7. doi: 10.1593/neo.03247. Neoplasia. 2004. PMID: 15140404 Free PMC article.

9

Current issues in the utility of 19F nuclear magnetic resonance methodologies for the assessment of tumour hypoxia.

Robinson SP, Griffiths JR. Robinson SP, et al. Among authors: griffiths jr. Philos Trans R Soc Lond B Biol Sci. 2004 Jun 29;359(1446):987-96. doi: 10.1098/rstb.2003.1376. Philos Trans R Soc Lond B Biol Sci. 2004. PMID: 15306411 Free PMC article. Review.

10

Tumor dose response to the vascular disrupting agent, 5,6-dimethylxanthenone-4-acetic acid, using in vivo magnetic resonance spectroscopy.

McPhail LD, Chung YL, Madhu B, Clark S, Griffiths JR, Kelland LR, Robinson SP. McPhail LD, et al. Among authors: griffiths jr. Clin Cancer Res. 2005 May 15;11(10):3705-13. doi: 10.1158/1078-0432.CCR-04-2504. Clin Cancer Res. 2005. PMID: 15897567

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