Toney JH - Search Results

1

Expression, purification, crystallization and preliminary X-ray analysis of Aeromonas hydrophilia metallo-beta-lactamase.

Sharma N, Toney JH, Fitzgerald PM. Sharma N, et al. Among authors: toney jh. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Feb 1;61(Pt 2):180-2. doi: 10.1107/S1744309104033512. Epub 2005 Jan 8. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005. PMID: 16510987 Free PMC article.

2

Unanticipated inhibition of the metallo-beta-lactamase from Bacteroides fragilis by 4-morpholineethanesulfonic acid (MES): a crystallographic study at 1.85-A resolution.

Fitzgerald PM, Wu JK, Toney JH. Fitzgerald PM, et al. Among authors: toney jh. Biochemistry. 1998 May 12;37(19):6791-800. doi: 10.1021/bi9730339. Biochemistry. 1998. PMID: 9578564

3

Succinic acids as potent inhibitors of plasmid-borne IMP-1 metallo-beta-lactamase.

Toney JH, Hammond GG, Fitzgerald PM, Sharma N, Balkovec JM, Rouen GP, Olson SH, Hammond ML, Greenlee ML, Gao YD. Toney JH, et al. J Biol Chem. 2001 Aug 24;276(34):31913-8. doi: 10.1074/jbc.M104742200. Epub 2001 Jun 4. J Biol Chem. 2001. PMID: 11390410 Free article.

4

Antibiotic sensitization using biphenyl tetrazoles as potent inhibitors of Bacteroides fragilis metallo-beta-lactamase.

Toney JH, Fitzgerald PM, Grover-Sharma N, Olson SH, May WJ, Sundelof JG, Vanderwall DE, Cleary KA, Grant SK, Wu JK, Kozarich JW, Pompliano DL, Hammond GG. Toney JH, et al. Chem Biol. 1998 Apr;5(4):185-96. doi: 10.1016/s1074-5521(98)90632-9. Chem Biol. 1998. PMID: 9545432

5

High-yield expression, purification, and characterization of active, soluble Bacteroides fragilis metallo-beta-lactamase, CcrA.

Toney JH, Wu JK, Overbye KM, Thompson CM, Pompliano DL. Toney JH, et al. Protein Expr Purif. 1997 Apr;9(3):355-62. doi: 10.1006/prep.1996.0718. Protein Expr Purif. 1997. PMID: 9126607

6

Structure-activity relationships of biphenyl tetrazoles as metallo-beta-lactamase inhibitors.

Toney JH, Cleary KA, Hammond GG, Yuan X, May WJ, Hutchins SM, Ashton WT, Vanderwall DE. Toney JH, et al. Bioorg Med Chem Lett. 1999 Sep 20;9(18):2741-6. doi: 10.1016/s0960-894x(99)00458-8. Bioorg Med Chem Lett. 1999. PMID: 10509927

7

Novel IMP-1 metallo-beta-lactamase inhibitors can reverse meropenem resistance in Escherichia coli expressing IMP-1.

Moloughney JG, D Thomas J, Toney JH. Moloughney JG, et al. Among authors: toney jh. FEMS Microbiol Lett. 2005 Feb 1;243(1):65-71. doi: 10.1016/j.femsle.2004.11.042. FEMS Microbiol Lett. 2005. PMID: 15668002

8

Inhibition of IMP-1 metallo-beta-lactamase and sensitization of IMP-1-producing bacteria by thioester derivatives.

Hammond GG, Huber JL, Greenlee ML, Laub JB, Young K, Silver LL, Balkovec JM, Pryor KD, Wu JK, Leiting B, Pompliano DL, Toney JH. Hammond GG, et al. Among authors: toney jh. FEMS Microbiol Lett. 1999 Oct 15;179(2):289-96. doi: 10.1111/j.1574-6968.1999.tb08740.x. FEMS Microbiol Lett. 1999. PMID: 10518728

9

Metallo-beta-lactamase inhibitors: promise for the future?

Toney JH, Moloughney JG. Toney JH, et al. Curr Opin Investig Drugs. 2004 Aug;5(8):823-6. Curr Opin Investig Drugs. 2004. PMID: 15600238 Review.

10

Inhibition of bacterial peptide deformylase by biaryl acid analogs.

Green BG, Toney JH, Kozarich JW, Grant SK. Green BG, et al. Among authors: toney jh. Arch Biochem Biophys. 2000 Mar 15;375(2):355-8. doi: 10.1006/abbi.1999.1673. Arch Biochem Biophys. 2000. PMID: 10700392

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