Gautier F - Search Results

1

The small organic compound HA14-1 prevents Bcl-2 interaction with Bax to sensitize malignant glioma cells to induction of cell death.

Manero F, Gautier F, Gallenne T, Cauquil N, Grée D, Cartron PF, Geneste O, Grée R, Vallette FM, Juin P. Manero F, et al. Among authors: gautier f. Cancer Res. 2006 Mar 1;66(5):2757-64. doi: 10.1158/0008-5472.CAN-05-2097. Cancer Res. 2006. PMID: 16510597

2

Bax activation by the BH3-only protein Puma promotes cell dependence on antiapoptotic Bcl-2 family members.

Gallenne T, Gautier F, Oliver L, Hervouet E, Noël B, Hickman JA, Geneste O, Cartron PF, Vallette FM, Manon S, Juin P. Gallenne T, et al. Among authors: gautier f. J Cell Biol. 2009 Apr 20;185(2):279-90. doi: 10.1083/jcb.200809153. J Cell Biol. 2009. PMID: 19380879 Free PMC article.

3

Decoding and unlocking the BCL-2 dependency of cancer cells.

Juin P, Geneste O, Gautier F, Depil S, Campone M. Juin P, et al. Among authors: gautier f. Nat Rev Cancer. 2013 Jul;13(7):455-65. doi: 10.1038/nrc3538. Epub 2013 Jun 20. Nat Rev Cancer. 2013. PMID: 23783119 Review.

4

Bax activation by engagement with, then release from, the BH3 binding site of Bcl-xL.

Gautier F, Guillemin Y, Cartron PF, Gallenne T, Cauquil N, Le Diguarher T, Casara P, Vallette FM, Manon S, Hickman JA, Geneste O, Juin P. Gautier F, et al. Mol Cell Biol. 2011 Feb;31(4):832-44. doi: 10.1128/MCB.00161-10. Epub 2010 Dec 20. Mol Cell Biol. 2011. PMID: 21173168 Free PMC article.

5

Opposite role of Bax and BCL-2 in the anti-tumoral responses of the immune system.

Bougras G, Cartron PF, Gautier F, Martin S, LeCabellec M, Meflah K, Gregoire M, Vallette FM. Bougras G, et al. Among authors: gautier f. BMC Cancer. 2004 Aug 24;4:54. doi: 10.1186/1471-2407-4-54. BMC Cancer. 2004. PMID: 15331018 Free PMC article.

6

The first alpha helix of Bax plays a necessary role in its ligand-induced activation by the BH3-only proteins Bid and PUMA.

Cartron PF, Gallenne T, Bougras G, Gautier F, Manero F, Vusio P, Meflah K, Vallette FM, Juin P. Cartron PF, et al. Among authors: gautier f. Mol Cell. 2004 Dec 3;16(5):807-18. doi: 10.1016/j.molcel.2004.10.028. Mol Cell. 2004. PMID: 15574335 Free article.

7

Structure-activity relationship of selected polyphenol derivatives as inhibitors of Bax/Bcl-xL interaction.

Vo DD, Gautier F, Juin P, Grée R. Vo DD, et al. Among authors: gautier f. Eur J Med Chem. 2012 May;51:286-93. doi: 10.1016/j.ejmech.2012.02.036. Epub 2012 Feb 25. Eur J Med Chem. 2012. PMID: 22425031

8

Design, synthesis and biological evaluation of new inhibitors of Bax/Bcl-xL interaction in cancer cells.

Vo DD, Gautier F, Barillé-Nion S, Juin P, Levoin N, Grée R. Vo DD, et al. Among authors: gautier f. Bioorg Med Chem Lett. 2014 Apr 1;24(7):1758-61. doi: 10.1016/j.bmcl.2014.02.035. Epub 2014 Feb 24. Bioorg Med Chem Lett. 2014. PMID: 24602902

9

Targeting PUMA/Bcl-xL interaction by new specific compounds to unleash apoptotic process in cancer cells.

Ramana Murthy AV, Narendar V, Kumar NS, Aparna P, Durga Bhavani AK, Gautier F, Barillé-Nion S, Juin P, Mosset P, Grée R, Levoin N. Ramana Murthy AV, et al. Among authors: gautier f. Eur J Med Chem. 2019 Jan 15;162:334-347. doi: 10.1016/j.ejmech.2018.10.069. Epub 2018 Nov 2. Eur J Med Chem. 2019. PMID: 30453244

10

c-Myc dependent expression of pro-apoptotic Bim renders HER2-overexpressing breast cancer cells dependent on anti-apoptotic Mcl-1.

Campone M, Noël B, Couriaud C, Grau M, Guillemin Y, Gautier F, Gouraud W, Charbonnel C, Campion L, Jézéquel P, Braun F, Barré B, Coqueret O, Barillé-Nion S, Juin P. Campone M, et al. Among authors: gautier f. Mol Cancer. 2011 Sep 7;10:110. doi: 10.1186/1476-4598-10-110. Mol Cancer. 2011. PMID: 21899728 Free PMC article.

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