Brugge JM - Search Results

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Protein S levels modulate the activated protein C resistance phenotype induced by elevated prothrombin levels.

Brugge JM, Tans G, Rosing J, Castoldi E. Brugge JM, et al. Thromb Haemost. 2006 Feb;95(2):236-42. doi: 10.1160/TH05-08-0582. Thromb Haemost. 2006. PMID: 16493484

Expression of the normal factor V allele modulates the APC resistance phenotype in heterozygous carriers of the factor V Leiden mutation.

Brugge JM, Simioni P, Bernardi F, Tormene D, Lunghi B, Tans G, Pagnan A, Rosing J, Castoldi E. Brugge JM, et al. J Thromb Haemost. 2005 Dec;3(12):2695-702. doi: 10.1111/j.1538-7836.2005.01634.x. J Thromb Haemost. 2005. PMID: 16359508 Free article.

Impaired APC cofactor activity of factor V plays a major role in the APC resistance associated with the factor V Leiden (R506Q) and R2 (H1299R) mutations.

Castoldi E, Brugge JM, Nicolaes GA, Girelli D, Tans G, Rosing J. Castoldi E, et al. Among authors: brugge jm. Blood. 2004 Jun 1;103(11):4173-9. doi: 10.1182/blood-2003-10-3578. Epub 2004 Feb 19. Blood. 2004. PMID: 14976057 Free article.

Theoretical and experimental study of the D2194G mutation in the C2 domain of coagulation factor V.

Miteva MA, Brugge JM, Rosing J, Nicolaes GA, Villoutreix BO. Miteva MA, et al. Among authors: brugge jm. Biophys J. 2004 Jan;86(1 Pt 1):488-98. doi: 10.1016/S0006-3495(04)74127-2. Biophys J. 2004. PMID: 14695293 Free PMC article.

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