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A high-throughput cell-based assay for inhibitors of ABCG2 activity.
Henrich CJ, Bokesch HR, Dean M, Bates SE, Robey RW, Goncharova EI, Wilson JA, McMahon JB. Henrich CJ, et al. Among authors: dean m. J Biomol Screen. 2006 Mar;11(2):176-83. doi: 10.1177/1087057105284576. Epub 2006 Feb 20. J Biomol Screen. 2006. PMID: 16490770
New inhibitors of ABCG2 identified by high-throughput screening.
Henrich CJ, Robey RW, Bokesch HR, Bates SE, Shukla S, Ambudkar SV, Dean M, McMahon JB. Henrich CJ, et al. Among authors: dean m. Mol Cancer Ther. 2007 Dec;6(12 Pt 1):3271-8. doi: 10.1158/1535-7163.MCT-07-0352. Mol Cancer Ther. 2007. PMID: 18089721 Free PMC article.
Mutational analysis of ABCG2: role of the GXXXG motif.
Polgar O, Robey RW, Morisaki K, Dean M, Michejda C, Sauna ZE, Ambudkar SV, Tarasova N, Bates SE. Polgar O, et al. Among authors: dean m. Biochemistry. 2004 Jul 27;43(29):9448-56. doi: 10.1021/bi0497953. Biochemistry. 2004. PMID: 15260487
Tumour stem cells and drug resistance.
Dean M, Fojo T, Bates S. Dean M, et al. Nat Rev Cancer. 2005 Apr;5(4):275-84. doi: 10.1038/nrc1590. Nat Rev Cancer. 2005. PMID: 15803154 Review.
ABCG2: a perspective.
Robey RW, To KK, Polgar O, Dohse M, Fetsch P, Dean M, Bates SE. Robey RW, et al. Among authors: dean m. Adv Drug Deliv Rev. 2009 Jan 31;61(1):3-13. doi: 10.1016/j.addr.2008.11.003. Epub 2008 Dec 16. Adv Drug Deliv Rev. 2009. PMID: 19135109 Free PMC article. Review.
Arginine 383 is a crucial residue in ABCG2 biogenesis.
Polgar O, Ediriwickrema LS, Robey RW, Sharma A, Hegde RS, Li Y, Xia D, Ward Y, Dean M, Ozvegy-Laczka C, Sarkadi B, Bates SE. Polgar O, et al. Among authors: dean m. Biochim Biophys Acta. 2009 Jul;1788(7):1434-43. doi: 10.1016/j.bbamem.2009.04.016. Epub 2009 May 3. Biochim Biophys Acta. 2009. PMID: 19406100 Free PMC article.
1,653 results