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Page 1
High-affinity AKAP7delta-protein kinase A interaction yields novel protein kinase A-anchoring disruptor peptides.
Hundsrucker C, Krause G, Beyermann M, Prinz A, Zimmermann B, Diekmann O, Lorenz D, Stefan E, Nedvetsky P, Dathe M, Christian F, McSorley T, Krause E, McConnachie G, Herberg FW, Scott JD, Rosenthal W, Klussmann E. Hundsrucker C, et al. Among authors: christian f. Biochem J. 2006 Jun 1;396(2):297-306. doi: 10.1042/BJ20051970. Biochem J. 2006. PMID: 16483255 Free PMC article.
Small molecule AKAP-protein kinase A (PKA) interaction disruptors that activate PKA interfere with compartmentalized cAMP signaling in cardiac myocytes.
Christian F, Szaszák M, Friedl S, Drewianka S, Lorenz D, Goncalves A, Furkert J, Vargas C, Schmieder P, Götz F, Zühlke K, Moutty M, Göttert H, Joshi M, Reif B, Haase H, Morano I, Grossmann S, Klukovits A, Verli J, Gáspár R, Noack C, Bergmann M, Kass R, Hampel K, Kashin D, Genieser HG, Herberg FW, Willoughby D, Cooper DM, Baillie GS, Houslay MD, von Kries JP, Zimmermann B, Rosenthal W, Klussmann E. Christian F, et al. J Biol Chem. 2011 Mar 18;286(11):9079-96. doi: 10.1074/jbc.M110.160614. Epub 2010 Dec 22. J Biol Chem. 2011. PMID: 21177871 Free PMC article.
Elucidation of a structural basis for the inhibitor-driven, p62 (SQSTM1)-dependent intracellular redistribution of cAMP phosphodiesterase-4A4 (PDE4A4).
Day JP, Lindsay B, Riddell T, Jiang Z, Allcock RW, Abraham A, Sookup S, Christian F, Bogum J, Martin EK, Rae RL, Anthony D, Rosair GM, Houslay DM, Huston E, Baillie GS, Klussmann E, Houslay MD, Adams DR. Day JP, et al. Among authors: christian f. J Med Chem. 2011 May 12;54(9):3331-47. doi: 10.1021/jm200070e. Epub 2011 Apr 13. J Med Chem. 2011. PMID: 21456625
Phosphodiesterase-8A binds to and regulates Raf-1 kinase.
Brown KM, Day JP, Huston E, Zimmermann B, Hampel K, Christian F, Romano D, Terhzaz S, Lee LC, Willis MJ, Morton DB, Beavo JA, Shimizu-Albergine M, Davies SA, Kolch W, Houslay MD, Baillie GS. Brown KM, et al. Among authors: christian f. Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):E1533-42. doi: 10.1073/pnas.1303004110. Epub 2013 Mar 18. Proc Natl Acad Sci U S A. 2013. PMID: 23509299 Free PMC article.
cAMP: novel concepts in compartmentalised signalling.
Edwards HV, Christian F, Baillie GS. Edwards HV, et al. Among authors: christian f. Semin Cell Dev Biol. 2012 Apr;23(2):181-90. doi: 10.1016/j.semcdb.2011.09.005. Epub 2011 Sep 13. Semin Cell Dev Biol. 2012. PMID: 21930230 Review.
74 results