Nakai H - Search Results

1

Discovery of a new chemical lead for a matrix metalloproteinase inhibitor.

Ikura M, Nakatani S, Yamamoto S, Habashita H, Sugiura T, Takahashi K, Ogawa K, Ohno H, Nakai H, Toda M. Ikura M, et al. Among authors: nakai h. Bioorg Med Chem. 2006 Jun 15;14(12):4241-52. doi: 10.1016/j.bmc.2006.01.059. Epub 2006 Feb 14. Bioorg Med Chem. 2006. PMID: 16481176

2

Design and synthesis of a selective EP4-receptor agonist. Part 1: discovery of 3,7-dithiaPGE1 derivatives and identification of their omega chains.

Maruyama T, Asada M, Shiraishi T, Egashira H, Yoshida H, Maruyama T, Ohuchida S, Nakai H, Kondo K, Toda M. Maruyama T, et al. Among authors: nakai h. Bioorg Med Chem. 2002 Apr;10(4):975-88. doi: 10.1016/s0968-0896(01)00351-0. Bioorg Med Chem. 2002. PMID: 11836107

3

Development of a highly selective EP2-receptor agonist. Part 1: identification of 16-hydroxy-17,17-trimethylene PGE2 derivatives.

Tani K, Naganawa A, Ishida A, Sagawa K, Harada H, Ogawa M, Maruyama T, Ohuchida S, Nakai H, Kondo K, Toda M. Tani K, et al. Among authors: nakai h. Bioorg Med Chem. 2002 Apr;10(4):1093-106. doi: 10.1016/s0968-0896(01)00369-8. Bioorg Med Chem. 2002. PMID: 11836120

4

Design and synthesis of a selective EP4-receptor agonist. Part 3: 16-phenyl-5-thiaPGE(1) and 9-beta-halo derivatives with improved stability.

Maruyama T, Asada M, Shiraishi T, Yoshida H, Maruyama T, Ohuchida S, Nakai H, Kondo K, Toda M. Maruyama T, et al. Among authors: nakai h. Bioorg Med Chem. 2002 Jun;10(6):1743-59. doi: 10.1016/s0968-0896(02)00031-7. Bioorg Med Chem. 2002. PMID: 11937333

5

Highly potent inhibitors of TNF-alpha production. Part 1: Discovery of chemical leads.

Matsui T, Kondo T, Nishita Y, Itadani S, Nakatani S, Omawari N, Sakai M, Nakazawa S, Ogata A, Ohno H, Obata T, Nakai H, Toda M. Matsui T, et al. Among authors: nakai h. Bioorg Med Chem Lett. 2002 Mar 25;12(6):903-5. doi: 10.1016/s0960-894x(02)00036-7. Bioorg Med Chem Lett. 2002. PMID: 11958990

6

Highly potent inhibitors of TNF-alpha production. Part I: discovery of new chemical leads and their structure-activity relationships.

Matsui T, Kondo T, Nishita Y, Itadani S, Nakatani S, Omawari N, Sakai M, Nakazawa S, Ogata A, Mori H, Terai K, Kamoshima W, Ohno H, Obata T, Nakai H, Toda M. Matsui T, et al. Among authors: nakai h. Bioorg Med Chem. 2002 Dec;10(12):3757-86. doi: 10.1016/s0968-0896(02)00381-4. Bioorg Med Chem. 2002. PMID: 12413832

7

Highly potent inhibitors of TNF-alpha production. Part II: metabolic stabilization of a newly found chemical lead and conformational analysis of an active diastereoisomer.

Matsui T, Kondo T, Nishita Y, Itadani S, Tsuruta H, Fujita S, Omawari N, Sakai M, Nakazawa S, Ogata A, Mori H, Kamoshima W, Terai K, Ohno H, Obata T, Nakai H, Toda M. Matsui T, et al. Among authors: nakai h. Bioorg Med Chem. 2002 Dec;10(12):3787-805. doi: 10.1016/s0968-0896(02)00380-2. Bioorg Med Chem. 2002. PMID: 12413833

8

Discovery of novel phosphonic acid derivatives as new chemical leads for inhibitors of TNF-alpha production.

Matsui T, Takahashi S, Matsunaga N, Nakamura K, Omawari N, Sakai M, Kamoshima W, Terai K, Ohno H, Obata T, Nakai H, Toda M. Matsui T, et al. Among authors: nakai h. Bioorg Med Chem. 2002 Dec;10(12):3807-15. doi: 10.1016/s0968-0896(02)00343-7. Bioorg Med Chem. 2002. PMID: 12413834

9

Synthesis, further biological evaluation and pharmacodynamics of newly discovered inhibitors of TNF-alpha production.

Matsui T, Kondo T, Nakatani S, Omawari N, Sakai M, Mori H, Ogata A, Kato J, Ohno H, Obata T, Nakai H, Toda M. Matsui T, et al. Among authors: nakai h. Bioorg Med Chem. 2003 Sep 1;11(18):3937-43. doi: 10.1016/s0968-0896(03)00409-7. Bioorg Med Chem. 2003. PMID: 12927854

10

Orally active PDE4 inhibitor with therapeutic potential.

Ochiai H, Ohtani T, Ishida A, Kishikawa K, Yamamoto S, Takeda H, Obata T, Nakai H, Toda M. Ochiai H, et al. Among authors: nakai h. Eur J Med Chem. 2004 Jul;39(7):555-71. doi: 10.1016/j.ejmech.2004.02.010. Eur J Med Chem. 2004. PMID: 15236836

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

1,182 results

Search Page

Filters