McKee RL - Search Results

1

Biological activity of parathyroid hormone antagonists substituted at position 13.

Chorev M, Roubini E, McKee RL, Gibbons SW, Reagan JE, Goldman ME, Caulfield MP, Rosenblatt M. Chorev M, et al. Among authors: mckee rl. Peptides. 1991 Jan-Feb;12(1):57-62. doi: 10.1016/0196-9781(91)90167-n. Peptides. 1991. PMID: 1647004

2

A novel, mild, specific and indirect maleimido-based radioiodolabeling method. Radiolabeling of analogs derived from parathyroid hormone (PTH) and PTH-related protein (PTHrP).

Chorev M, Caulfield MP, Roubini E, McKee RL, Gibbons SW, Leu CT, Levy JJ, Rosenblatt M. Chorev M, et al. Among authors: mckee rl. Int J Pept Protein Res. 1992 Nov;40(5):445-55. Int J Pept Protein Res. 1992. PMID: 1336486

3

Cyclic parathyroid hormone related protein antagonists: lysine 13 to aspartic acid 17 [i to (i + 4)] side chain to side chain lactamization.

Chorev M, Roubini E, McKee RL, Gibbons SW, Goldman ME, Caulfield MP, Rosenblatt M. Chorev M, et al. Among authors: mckee rl. Biochemistry. 1991 Jun 18;30(24):5968-74. doi: 10.1021/bi00238a022. Biochemistry. 1991. PMID: 1646005

4

Effects of hydrophobic substitutions at position 18 on the potency of parathyroid hormone antagonists.

Chorev M, Roubini E, Goldman ME, McKee RL, Gibbons SW, Reagan JE, Caulfield MP, Rosenblatt M. Chorev M, et al. Among authors: mckee rl. Int J Pept Protein Res. 1990 Nov;36(5):465-70. doi: 10.1111/j.1399-3011.1990.tb01307.x. Int J Pept Protein Res. 1990. PMID: 2177456

5

Removal of partial agonism from parathyroid hormone (PTH)-related protein-(7-34)NH2 by substitution of PTH amino acids at positions 10 and 11.

Nutt RF, Caulfield MP, Levy JJ, Gibbons SW, Rosenblatt M, McKee RL. Nutt RF, et al. Among authors: mckee rl. Endocrinology. 1990 Jul;127(1):491-3. doi: 10.1210/endo-127-1-491. Endocrinology. 1990. PMID: 2163325

6

Treatment of bone-derived ROS 17/2.8 cells with dexamethasone and pertussis toxin enables detection of partial agonist activity for parathyroid hormone antagonists.

McKee RL, Caulfield MP, Rosenblatt M. McKee RL, et al. Endocrinology. 1990 Jul;127(1):76-82. doi: 10.1210/endo-127-1-76. Endocrinology. 1990. PMID: 2163326

7

The bovine renal parathyroid hormone (PTH) receptor has equal affinity for two different amino acid sequences: the receptor binding domains of PTH and PTH-related protein are located within the 14-34 region.

Caulfield MP, McKee RL, Goldman ME, Duong LT, Fisher JE, Gay CT, DeHaven PA, Levy JJ, Roubini E, Nutt RF, et al. Caulfield MP, et al. Among authors: mckee rl. Endocrinology. 1990 Jul;127(1):83-7. doi: 10.1210/endo-127-1-83. Endocrinology. 1990. PMID: 2163327

8

Modifications of position 12 in parathyroid hormone and parathyroid hormone related protein: toward the design of highly potent antagonists.

Chorev M, Goldman ME, McKee RL, Roubini E, Levy JJ, Gay CT, Reagan JE, Fisher JE, Caporale LH, Golub EE, et al. Chorev M, et al. Among authors: mckee rl. Biochemistry. 1990 Feb 13;29(6):1580-6. doi: 10.1021/bi00458a032. Biochemistry. 1990. PMID: 2334716

9

The 7-34-fragment of human hypercalcemia factor is a partial agonist/antagonist for parathyroid hormone-stimulated cAMP production.

McKee RL, Goldman ME, Caulfield MP, DeHaven PA, Levy JJ, Nutt RF, Rosenblatt M. McKee RL, et al. Endocrinology. 1988 Jun;122(6):3008-10. doi: 10.1210/endo-122-6-3008. Endocrinology. 1988. PMID: 2836181

10

A new highly potent parathyroid hormone antagonist: [D-Trp12,Tyr34]bPTH-(7-34)NH2.

Goldman ME, McKee RL, Caulfield MP, Reagan JE, Levy JJ, Gay CT, DeHaven PA, Rosenblatt M, Chorev M. Goldman ME, et al. Among authors: mckee rl. Endocrinology. 1988 Nov;123(5):2597-9. doi: 10.1210/endo-123-5-2597. Endocrinology. 1988. PMID: 2844517

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