Keogh JM - Search Results

1

A POMC variant implicates beta-melanocyte-stimulating hormone in the control of human energy balance.

Lee YS, Challis BG, Thompson DA, Yeo GS, Keogh JM, Madonna ME, Wraight V, Sims M, Vatin V, Meyre D, Shield J, Burren C, Ibrahim Z, Cheetham T, Swift P, Blackwood A, Hung CC, Wareham NJ, Froguel P, Millhauser GL, O'Rahilly S, Farooqi IS. Lee YS, et al. Among authors: keogh jm. Cell Metab. 2006 Feb;3(2):135-40. doi: 10.1016/j.cmet.2006.01.006. Cell Metab. 2006. PMID: 16459314 Free article.

2

Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiency.

Farooqi IS, Yeo GS, Keogh JM, Aminian S, Jebb SA, Butler G, Cheetham T, O'Rahilly S. Farooqi IS, et al. Among authors: keogh jm. J Clin Invest. 2000 Jul;106(2):271-9. doi: 10.1172/JCI9397. J Clin Invest. 2000. PMID: 10903343 Free PMC article.

3

The CART gene and human obesity: mutational analysis and population genetics.

Challis BG, Yeo GS, Farooqi IS, Luan J, Aminian S, Halsall DJ, Keogh JM, Wareham NJ, O'Rahilly S. Challis BG, et al. Among authors: keogh jm. Diabetes. 2000 May;49(5):872-5. doi: 10.2337/diabetes.49.5.872. Diabetes. 2000. PMID: 10905499

4

Uncoupling protein 3 genetic variants in human obesity: the c-55t promoter polymorphism is negatively correlated with body mass index in a UK Caucasian population.

Halsall DJ, Luan J, Saker P, Huxtable S, Farooqi IS, Keogh J, Wareham NJ, O'Rahilly S. Halsall DJ, et al. Int J Obes Relat Metab Disord. 2001 Apr;25(4):472-7. doi: 10.1038/sj.ijo.0801584. Int J Obes Relat Metab Disord. 2001. PMID: 11319649

5

Partial leptin deficiency and human adiposity.

Farooqi IS, Keogh JM, Kamath S, Jones S, Gibson WT, Trussell R, Jebb SA, Lip GY, O'Rahilly S. Farooqi IS, et al. Among authors: keogh jm. Nature. 2001 Nov 1;414(6859):34-5. doi: 10.1038/35102112. Nature. 2001. PMID: 11689931

6

A missense mutation disrupting a dibasic prohormone processing site in pro-opiomelanocortin (POMC) increases susceptibility to early-onset obesity through a novel molecular mechanism.

Challis BG, Pritchard LE, Creemers JW, Delplanque J, Keogh JM, Luan J, Wareham NJ, Yeo GS, Bhattacharyya S, Froguel P, White A, Farooqi IS, O'Rahilly S. Challis BG, et al. Among authors: keogh jm. Hum Mol Genet. 2002 Aug 15;11(17):1997-2004. doi: 10.1093/hmg/11.17.1997. Hum Mol Genet. 2002. PMID: 12165561

7

Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency.

Farooqi IS, Matarese G, Lord GM, Keogh JM, Lawrence E, Agwu C, Sanna V, Jebb SA, Perna F, Fontana S, Lechler RI, DePaoli AM, O'Rahilly S. Farooqi IS, et al. Among authors: keogh jm. J Clin Invest. 2002 Oct;110(8):1093-103. doi: 10.1172/JCI15693. J Clin Invest. 2002. PMID: 12393845 Free PMC article.

8

Mutations in the human melanocortin-4 receptor gene associated with severe familial obesity disrupts receptor function through multiple molecular mechanisms.

Yeo GS, Lank EJ, Farooqi IS, Keogh J, Challis BG, O'Rahilly S. Yeo GS, et al. Hum Mol Genet. 2003 Mar 1;12(5):561-74. doi: 10.1093/hmg/ddg057. Hum Mol Genet. 2003. PMID: 12588803

9

Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene.

Farooqi IS, Keogh JM, Yeo GS, Lank EJ, Cheetham T, O'Rahilly S. Farooqi IS, et al. Among authors: keogh jm. N Engl J Med. 2003 Mar 20;348(12):1085-95. doi: 10.1056/NEJMoa022050. N Engl J Med. 2003. PMID: 12646665 Free article.

10

Contribution of variants in the small heterodimer partner gene to birthweight, adiposity, and insulin levels: mutational analysis and association studies in multiple populations.

Hung CC, Farooqi IS, Ong K, Luan J, Keogh JM, Pembrey M, Yeo GS, Dunger D, Wareham NJ, O' Rahilly S. Hung CC, et al. Among authors: keogh jm. Diabetes. 2003 May;52(5):1288-91. doi: 10.2337/diabetes.52.5.1288. Diabetes. 2003. PMID: 12716767

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