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Fusion of the upstream vpu sequences to the env of simian human immunodeficiency virus (SHIV(KU-1bMC33)) results in the synthesis of two envelope precursor proteins, increased numbers of virus particles associated with the cell surface and is pathogenic for pig-tailed macaques.
Hout DR, Gomez ML, Pacyniak E, Mulcahy ER, Gomez LM, Jackson M, Flick M, Fegley B, McCormick C, Wisdom BJ, Culley N, Pinson DM, Powers M, Wong SW, Stephens EB. Hout DR, et al. Among authors: gomez ml, gomez lm. Virology. 2004 May 20;323(1):91-107. doi: 10.1016/j.virol.2004.02.028. Virology. 2004. PMID: 15165822 Free article.
Identification of a region within the cytoplasmic domain of the subtype B Vpu protein of human immunodeficiency virus type 1 (HIV-1) that is responsible for retention in the golgi complex and its absence in the Vpu protein from a subtype C HIV-1.
Pacyniak E, Gomez ML, Gomez LM, Mulcahy ER, Jackson M, Hout DR, Wisdom BJ, Stephens EB. Pacyniak E, et al. Among authors: gomez ml, gomez lm. AIDS Res Hum Retroviruses. 2005 May;21(5):379-94. doi: 10.1089/aid.2005.21.379. AIDS Res Hum Retroviruses. 2005. PMID: 15929700
Scrambling of the amino acids within the transmembrane domain of Vpu results in a simian-human immunodeficiency virus (SHIVTM) that is less pathogenic for pig-tailed macaques.
Hout DR, Gomez ML, Pacyniak E, Gomez LM, Inbody SH, Mulcahy ER, Culley N, Pinson DM, Powers MF, Wong SW, Stephens EB. Hout DR, et al. Among authors: gomez ml, gomez lm. Virology. 2005 Aug 15;339(1):56-69. doi: 10.1016/j.virol.2005.04.038. Virology. 2005. PMID: 15975620 Free article.
Substitution of the transmembrane domain of Vpu in simian-human immunodeficiency virus (SHIVKU1bMC33) with that of M2 of influenza A results in a virus that is sensitive to inhibitors of the M2 ion channel and is pathogenic for pig-tailed macaques.
Hout DR, Gomez ML, Pacyniak E, Gomez LM, Fegley B, Mulcahy ER, Hill MS, Culley N, Pinson DM, Nothnick W, Powers MF, Wong SW, Stephens EB. Hout DR, et al. Among authors: gomez ml, gomez lm. Virology. 2006 Jan 20;344(2):541-59. doi: 10.1016/j.virol.2005.08.022. Epub 2005 Sep 30. Virology. 2006. PMID: 16199074 Free article.
GENCODE 2025: reference gene annotation for human and mouse.
Mudge JM, Carbonell-Sala S, Diekhans M, Martinez JG, Hunt T, Jungreis I, Loveland JE, Arnan C, Barnes I, Bennett R, Berry A, Bignell A, Cerdán-Vélez D, Cochran K, Cortés LT, Davidson C, Donaldson S, Dursun C, Fatima R, Hardy M, Hebbar P, Hollis Z, James BT, Jiang Y, Johnson R, Kaur G, Kay M, Mangan RJ, Maquedano M, Gómez LM, Mathlouthi N, Merritt R, Ni P, Palumbo E, Perteghella T, Pozo F, Raj S, Sisu C, Steed E, Sumathipala D, Suner MM, Uszczynska-Ratajczak B, Wass E, Yang YT, Zhang D, Finn RD, Gerstein M, Guigó R, Hubbard TJP, Kellis M, Kundaje A, Paten B, Tress ML, Birney E, Martin FJ, Frankish A. Mudge JM, et al. Among authors: gomez lm. Nucleic Acids Res. 2025 Jan 6;53(D1):D966-D975. doi: 10.1093/nar/gkae1078. Nucleic Acids Res. 2025. PMID: 39565199 Free PMC article.
128 results