Coleman CS - Search Results

1

Structures of wild-type and mutant human spermidine/spermine N1-acetyltransferase, a potential therapeutic drug target.

Bewley MC, Graziano V, Jiang J, Matz E, Studier FW, Pegg AE, Coleman CS, Flanagan JM. Bewley MC, et al. Among authors: coleman cs. Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2063-8. doi: 10.1073/pnas.0511008103. Epub 2006 Feb 2. Proc Natl Acad Sci U S A. 2006. PMID: 16455797 Free PMC article.

2

Spermidine/spermine-N1-acetyltransferase-2 (SSAT2) acetylates thialysine and is not involved in polyamine metabolism.

Coleman CS, Stanley BA, Jones AD, Pegg AE. Coleman CS, et al. Biochem J. 2004 Nov 15;384(Pt 1):139-48. doi: 10.1042/BJ20040790. Biochem J. 2004. PMID: 15283699 Free PMC article.

3

Spermidine/spermine N1-acetyltransferase specifically binds to the integrin alpha9 subunit cytoplasmic domain and enhances cell migration.

Chen C, Young BA, Coleman CS, Pegg AE, Sheppard D. Chen C, et al. Among authors: coleman cs. J Cell Biol. 2004 Oct 11;167(1):161-70. doi: 10.1083/jcb.200312166. J Cell Biol. 2004. PMID: 15479742 Free PMC article.

4

Role of the carboxyl terminal MATEE sequence of spermidine/spermine N1-acetyltransferase in the activity and stabilization by the polyamine analog N1,N12-bis(ethyl)spermine.

Coleman CS, Huang H, Pegg AE. Coleman CS, et al. Biochemistry. 1995 Oct 17;34(41):13423-30. doi: 10.1021/bi00041a020. Biochemistry. 1995. PMID: 7577929

5

Structure and critical residues at the active site of spermidine/spermine-N1-acetyltransferase.

Coleman CS, Huang H, Pegg AE. Coleman CS, et al. Biochem J. 1996 Jun 15;316 ( Pt 3)(Pt 3):697-701. doi: 10.1042/bj3160697. Biochem J. 1996. PMID: 8670140 Free PMC article.

6

Proteasomal degradation of spermidine/spermine N1-acetyltransferase requires the carboxyl-terminal glutamic acid residues.

Coleman CS, Pegg AE. Coleman CS, et al. J Biol Chem. 1997 May 2;272(18):12164-9. doi: 10.1074/jbc.272.18.12164. J Biol Chem. 1997. PMID: 9115288 Free article.

7

Properties and regulation of human spermidine/spermine N1-acetyltransferase stably expressed in Chinese hamster ovary cells.

McCloskey DE, Coleman CS, Pegg AE. McCloskey DE, et al. Among authors: coleman cs. J Biol Chem. 1999 Mar 5;274(10):6175-82. doi: 10.1074/jbc.274.10.6175. J Biol Chem. 1999. PMID: 10037702 Free article.

8

Polyamine analogues inhibit the ubiquitination of spermidine/spermine N1-acetyltransferase and prevent its targeting to the proteasome for degradation.

Coleman CS, Pegg AE. Coleman CS, et al. Biochem J. 2001 Aug 15;358(Pt 1):137-45. doi: 10.1042/0264-6021:3580137. Biochem J. 2001. PMID: 11485561 Free PMC article.

9

Targeted expression of spermidine/spermine N1-acetyltransferase increases susceptibility to chemically induced skin carcinogenesis.

Coleman CS, Pegg AE, Megosh LC, Guo Y, Sawicki JA, O'Brien TG. Coleman CS, et al. Carcinogenesis. 2002 Feb;23(2):359-64. doi: 10.1093/carcin/23.2.359. Carcinogenesis. 2002. PMID: 11872645

10

Studies of the mechanism by which increased spermidine/spermine N1-acetyltransferase activity increases susceptibility to skin carcinogenesis.

Wang X, Feith DJ, Welsh P, Coleman CS, Lopez C, Woster PM, O'Brien TG, Pegg AE. Wang X, et al. Among authors: coleman cs. Carcinogenesis. 2007 Nov;28(11):2404-11. doi: 10.1093/carcin/bgm162. Epub 2007 Aug 3. Carcinogenesis. 2007. PMID: 17675337

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