Communication between the regulatory and the catalytic region of the cAMP-responsive guanine nucleotide exchange factor Epac.
Rehmann H, Rueppel A, Bos JL, Wittinghofer A.
Rehmann H, et al. Among authors: wittinghofer a.
J Biol Chem. 2003 Jun 27;278(26):23508-14. doi: 10.1074/jbc.M301680200. Epub 2003 Apr 21.
J Biol Chem. 2003.
PMID: 12707263
Free article.
This protein consists of a regulatory region with a cAMP-binding domain and a catalytic region that mediates the GEF activity. ...L., and Wittinghofer, A. (2003) Nat. Struct. Biol. 10, 26-32). Here we show that mutations of conserved residues in …
This protein consists of a regulatory region with a cAMP-binding domain and a catalytic region that mediates the GEF ac …