Kozikowski AP - Search Results

1

Synthesis and structure-activity relationships of 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine analogues as potent, noncompetitive metabotropic glutamate receptor subtype 5 antagonists; search for cocaine medications.

Iso Y, Grajkowska E, Wroblewski JT, Davis J, Goeders NE, Johnson KM, Sanker S, Roth BL, Tueckmantel W, Kozikowski AP. Iso Y, et al. Among authors: kozikowski ap. J Med Chem. 2006 Feb 9;49(3):1080-100. doi: 10.1021/jm050570f. J Med Chem. 2006. PMID: 16451073

2

Synthesis of urea-based inhibitors as active site probes of glutamate carboxypeptidase II: efficacy as analgesic agents.

Kozikowski AP, Zhang J, Nan F, Petukhov PA, Grajkowska E, Wroblewski JT, Yamamoto T, Bzdega T, Wroblewska B, Neale JH. Kozikowski AP, et al. J Med Chem. 2004 Mar 25;47(7):1729-38. doi: 10.1021/jm0306226. J Med Chem. 2004. PMID: 15027864

3

Synthesis, molecular modeling, and biological studies of novel piperidine-based analogues of cocaine: evidence of unfavorable interactions proximal to the 3alpha-position of the piperidine ring.

Petukhov PA, Zhang J, Wang CZ, Ye YP, Johnson KM, Kozikowski AP. Petukhov PA, et al. Among authors: kozikowski ap. J Med Chem. 2004 Jun 3;47(12):3009-18. doi: 10.1021/jm0303296. J Med Chem. 2004. PMID: 15163183

4

Further structure-activity relationship studies of piperidine-based monoamine transporter inhibitors: effects of piperidine ring stereochemistry on potency. Identification of norepinephrine transporter selective ligands and broad-spectrum transporter inhibitors.

He R, Kurome T, Giberson KM, Johnson KM, Kozikowski AP. He R, et al. Among authors: kozikowski ap. J Med Chem. 2005 Dec 15;48(25):7970-9. doi: 10.1021/jm050694s. J Med Chem. 2005. PMID: 16335921

5

Synthesis and pharmacological evaluation of novel 9- and 10-substituted cytisine derivatives. Nicotinic ligands of enhanced subtype selectivity.

Chellappan SK, Xiao Y, Tueckmantel W, Kellar KJ, Kozikowski AP. Chellappan SK, et al. Among authors: kozikowski ap. J Med Chem. 2006 May 4;49(9):2673-6. doi: 10.1021/jm051196m. J Med Chem. 2006. PMID: 16640326 Free PMC article.

6

Selective 5-hydroxytryptamine 2C receptor agonists derived from the lead compound tranylcypromine: identification of drugs with antidepressant-like action.

Cho SJ, Jensen NH, Kurome T, Kadari S, Manzano ML, Malberg JE, Caldarone B, Roth BL, Kozikowski AP. Cho SJ, et al. Among authors: kozikowski ap. J Med Chem. 2009 Apr 9;52(7):1885-902. doi: 10.1021/jm801354e. J Med Chem. 2009. PMID: 19284718 Free PMC article.

7

Design and Discovery of Functionally Selective Serotonin 2C (5-HT_2C) Receptor Agonists.

Cheng J, McCorvy JD, Giguere PM, Zhu H, Kenakin T, Roth BL, Kozikowski AP. Cheng J, et al. Among authors: kozikowski ap. J Med Chem. 2016 Nov 10;59(21):9866-9880. doi: 10.1021/acs.jmedchem.6b01194. Epub 2016 Oct 25. J Med Chem. 2016. PMID: 27726356

8

SAR studies of piperidine-based analogues of cocaine. 4. Effect of N-modification and ester replacement.

Petukhov PA, Zhang J, Kozikowski AP, Wang CZ, Ye YP, Johnson KM, Tella SR. Petukhov PA, et al. Among authors: kozikowski ap. J Med Chem. 2002 Jul 18;45(15):3161-70. doi: 10.1021/jm0200153. J Med Chem. 2002. PMID: 12109901

9

alpha-substituted quisqualic acid analogs: new metabotropic glutamate receptor group II selective antagonists.

Kozikowski AP, Steensma D, Varasi M, Pshenichkin S, Surina E, Wroblewski JT. Kozikowski AP, et al. Bioorg Med Chem Lett. 1998 Mar 3;8(5):447-52. doi: 10.1016/s0960-894x(98)00052-3. Bioorg Med Chem Lett. 1998. PMID: 9871596 Free article.

10

Chemical synthesis and pharmacology of 6- and 7-hydroxylated 2-carbomethoxy-3-(p-tolyl)tropanes: antagonism of cocaine's locomotor stimulant effects.

Zhao L, Johnson KM, Zhang M, Flippen-Anderson J, Kozikowski AP. Zhao L, et al. Among authors: kozikowski ap. J Med Chem. 2000 Aug 24;43(17):3283-94. doi: 10.1021/jm000141b. J Med Chem. 2000. PMID: 10966747

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

346 results

Search Page

Filters