Fagan P - Search Results

1

2',3'-dideoxynucleoside 5'-beta, gamma-(difluoromethylene) triphosphates with alpha-P-thio or alpha-P-seleno modifications: synthesis and their inhibition of HIV-1 reverse transcriptase.

Boyle NA, Fagan P, Brooks JL, Prhavc M, Lambert J, Cook PD. Boyle NA, et al. Among authors: fagan p. Nucleosides Nucleotides Nucleic Acids. 2005;24(10-12):1651-64. doi: 10.1080/15257770500267055. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 16438041

2

Synthesis of azole nucleoside 5'-monophosphate mimics (P1Ms) and their inhibitory properties of IMP dehydrogenases.

Wang G, Sakthivel K, Rajappan V, Bruice TW, Tucker K, Fagan P, Brooks JL, Hurd T, Leeds JM, Cook PD. Wang G, et al. Among authors: fagan p. Nucleosides Nucleotides Nucleic Acids. 2004;23(1-2):317-37. doi: 10.1081/ncn-120027838. Nucleosides Nucleotides Nucleic Acids. 2004. PMID: 15043157

3

Synthesis of AZT 5'-triphosphate mimics and their inhibitory effects on HIV-1 reverse transcriptase.

Wang G, Boyle N, Chen F, Rajappan V, Fagan P, Brooks JL, Hurd T, Leeds JM, Rajwanshi VK, Jin Y, Prhavc M, Bruice TW, Cook PD. Wang G, et al. Among authors: fagan p. J Med Chem. 2004 Dec 30;47(27):6902-13. doi: 10.1021/jm040116w. J Med Chem. 2004. PMID: 15615539

4

Synthesis of 2',3'-dideoxynucleoside 5'-alpha-P-borano-beta,gamma-(difluoromethylene)triphosphates and their inhibition of HIV-1 reverse transcriptase.

Boyle NA, Rajwanshi VK, Prhavc M, Wang G, Fagan P, Chen F, Ewing GJ, Brooks JL, Hurd T, Leeds JM, Bruice TW, Cook PD. Boyle NA, et al. Among authors: fagan p. J Med Chem. 2005 Apr 7;48(7):2695-700. doi: 10.1021/jm040101y. J Med Chem. 2005. PMID: 15801860

5

Synthesis of 5'-triphosphate mimics (P3Ms) of 3'-azido-3',5'-dideoxythymidine and 3',5'-dideoxy-5'-difluoromethylenethymidine as HIV-1 reverse transcriptase inhibitors.

Rajwanshi VK, Prhavc M, Fagan P, Brooks JL, Hurd T, Cook PD, Wang G. Rajwanshi VK, et al. Among authors: fagan p. Nucleosides Nucleotides Nucleic Acids. 2005;24(3):179-89. doi: 10.1081/NCN-55707. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 15892257

6

The binding modes of a rationally designed photoactivated DNA nuclease determined by NMR.

Spielmann HP, Fagan PA, Bregant TM, Little RD, Wemmer DE. Spielmann HP, et al. Among authors: fagan pa. Nucleic Acids Res. 1995 May 11;23(9):1576-83. doi: 10.1093/nar/23.9.1576. Nucleic Acids Res. 1995. PMID: 7784213 Free PMC article.

7

An NMR study of [d(CGCGAATTCGCG)]2 containing an interstrand cross-link derived from a distamycin-pyrrole conjugate.

Fagan PA, Spielmann HP, Sigurdsson S, Rink SM, Hopkins PB, Wemmer DE. Fagan PA, et al. Nucleic Acids Res. 1996 Apr 15;24(8):1566-73. doi: 10.1093/nar/24.8.1566. Nucleic Acids Res. 1996. PMID: 8628693 Free PMC article.

8

NMR study of the conformation of the 2-aminopurine:cytosine mismatch in DNA.

Fagan PA, Fàbrega C, Eritja R, Goodman MF, Wemmer DE. Fagan PA, et al. Biochemistry. 1996 Apr 2;35(13):4026-33. doi: 10.1021/bi952657g. Biochemistry. 1996. PMID: 8672436

9

A simple method for N-15 labelling of exocyclic amino groups in synthetic oligodeoxynucleotides.

Acedo M, Fàbrega C, Aviño A, Goodman M, Fagan P, Wemmer D, Eritja R. Acedo M, et al. Among authors: fagan p. Nucleic Acids Res. 1994 Aug 11;22(15):2982-9. doi: 10.1093/nar/22.15.2982. Nucleic Acids Res. 1994. PMID: 8065910 Free PMC article.

10

NMR structural refinement of a tandem G.A mismatched decamer d(CCAAGATTGG)2 via the hybrid matrix procedure.

Nikonowicz EP, Meadows RP, Fagan P, Gorenstein DG. Nikonowicz EP, et al. Among authors: fagan p. Biochemistry. 1991 Feb 5;30(5):1323-34. doi: 10.1021/bi00219a024. Biochemistry. 1991. PMID: 1991114

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