Wu M - Search Results

1

Synthesis of 9-[1-(substituted)-2-(phosphonomethoxy)ethyl]adenine derivatives as possible antiviral agents.

Wu M, El-Kattan Y, Lin TH, Ghosh A, Kumar VS, Kotian PL, Cheng X, Bantia S, Babu YS, Chand P. Wu M, et al. Nucleosides Nucleotides Nucleic Acids. 2005;24(10-12):1569-85. doi: 10.1080/15257770500265315. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 16438035

2

Synthesis of 9-[1-(substituted)-3-(phosphonomethoxy)propyl]adenine derivatives as possible antiviral agents.

Wu M, El-Kattan Y, Lin TH, Ghosh A, Vadlakonda S, Kotian PL, Babu YS, Chand P. Wu M, et al. Nucleosides Nucleotides Nucleic Acids. 2005;24(10-12):1543-68. doi: 10.1080/15257770500268673. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 16438034

3

Synthesis of 9-[1-(1 -hydroxyethyl)-3-(phosphonomethoxy)propyl]adenine and prodrug as possible antiviral agents.

Ghosh A, El-Kattan Y, Wu M, Lin TH, Vadlakonda S, Kotian PL, Babu YS, Chand P. Ghosh A, et al. Among authors: wu m. Nucleosides Nucleotides Nucleic Acids. 2005;24(10-12):1587-95. doi: 10.1080/15257770500265612. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 16438036

4

Synthesis of N6-substituted 9-[3-(phosphonomethoxy)propyl]adenine derivatives as possible antiviral agents.

El-Kattan Y, Lin TH, Wu M, Kumar VS, Kotian PL, Ghosh A, Cheng X, Bantia S, Babu YS, Chand P. El-Kattan Y, et al. Among authors: wu m. Nucleosides Nucleotides Nucleic Acids. 2005;24(10-12):1597-611. doi: 10.1080/15257770500265760. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 16438037

5

An efficient synthesis of acyclic N7- and N9-adenine nucleosides via alkylation with secondary carbon electrophiles to introduce versatile functional groups at the C-1 position of acyclic moiety.

Kotian PL, Kumar VS, Lin TH, El-Kattan Y, Ghosh A, Wu M, Cheng X, Bantia S, Babu YS, Chand P. Kotian PL, et al. Among authors: wu m. Nucleosides Nucleotides Nucleic Acids. 2006;25(2):121-40. doi: 10.1080/15257770500446816. Nucleosides Nucleotides Nucleic Acids. 2006. PMID: 16541957

6

Berotralstat (BCX7353): Structure-Guided Design of a Potent, Selective, and Oral Plasma Kallikrein Inhibitor to Prevent Attacks of Hereditary Angioedema (HAE).

Kotian PL, Wu M, Vadlakonda S, Chintareddy V, Lu P, Juarez L, Kellogg-Yelder D, Chen X, Muppa S, Chambers-Wilson R, Davis Parker C, Williams J, Polach KJ, Zhang W, Raman K, Babu YS. Kotian PL, et al. Among authors: wu m. J Med Chem. 2021 Sep 9;64(17):12453-12468. doi: 10.1021/acs.jmedchem.1c00511. Epub 2021 Aug 26. J Med Chem. 2021. PMID: 34436898

7

Discovery and optimization of orally bioavailable and potent plasma Kallikrein inhibitors bearing a quaternary carbon.

Zhang W, Vadlakonda S, Wu M, Chintareddy V, Vogeti LN, Juarez L, Muppa S, Parker C, Kellogg-Yelder D, Williams J, Polach K, Chen X, Raman K, Babu YS, Kotian P. Zhang W, et al. Among authors: wu m. Bioorg Med Chem. 2022 Nov 1;73:117035. doi: 10.1016/j.bmc.2022.117035. Epub 2022 Sep 30. Bioorg Med Chem. 2022. PMID: 36208543

8

Scaffold hopping via ring opening enables identification of acyclic compounds as new complement Factor D inhibitors.

Zhang W, Wu M, Vadlakonda S, Juarez L, Cheng X, Muppa S, Chintareddy V, Vogeti L, Kellogg-Yelder D, Williams J, Polach K, Chen X, Raman K, Babu YS, Kotian P. Zhang W, et al. Among authors: wu m. Bioorg Med Chem. 2022 Nov 15;74:117034. doi: 10.1016/j.bmc.2022.117034. Epub 2022 Oct 9. Bioorg Med Chem. 2022. PMID: 36272185

9

Synthesis of novel azasugar-containing 2'β-C-Me 9-deaza nucleosides as potential anti-hepatitis C virus agents.

Kotian PL, Wu M, Ghosh A, Polach KJ, El-Kattan Y, Kumar VS, Lin TH, Cheng X, Bantia S, Raman K, Chand P, Babu YS. Kotian PL, et al. Among authors: wu m. Nucleosides Nucleotides Nucleic Acids. 2023;42(4):317-327. doi: 10.1080/15257770.2022.2142609. Epub 2022 Nov 10. Nucleosides Nucleotides Nucleic Acids. 2023. PMID: 36354089

10

Synthesis and biological evaluation of Ribo 7-N/O/S pyrimidine 9-deaza C-nucleoside analogs as new antiviral agents for inhibiting HCV RNA-dependent RNA polymerases.

Wu M, Vadlakonda S, El-Kattan Y, Ghosh A, Lin TH, Chambers-Wilson R, Cheng X, Bantia S, Kellogg-Yelder D, Chand P, Babu YS, Kotian PL. Wu M, et al. Eur J Med Chem. 2024 Jan 15;264:115991. doi: 10.1016/j.ejmech.2023.115991. Epub 2023 Nov 29. Eur J Med Chem. 2024. PMID: 38118393

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