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Human monoclonal anti-protective antigen antibody completely protects rabbits and is synergistic with ciprofloxacin in protecting mice and guinea pigs against inhalation anthrax.
Peterson JW, Comer JE, Noffsinger DM, Wenglikowski A, Walberg KG, Chatuev BM, Chopra AK, Stanberry LR, Kang AS, Scholz WW, Sircar J. Peterson JW, et al. Among authors: noffsinger dm. Infect Immun. 2006 Feb;74(2):1016-24. doi: 10.1128/IAI.74.2.1016-1024.2006. Infect Immun. 2006. PMID: 16428748 Free PMC article.
Human monoclonal antibody AVP-21D9 to protective antigen reduces dissemination of the Bacillus anthracis Ames strain from the lungs in a rabbit model.
Peterson JW, Comer JE, Baze WB, Noffsinger DM, Wenglikowski A, Walberg KG, Hardcastle J, Pawlik J, Bush K, Taormina J, Moen S, Thomas J, Chatuev BM, Sower L, Chopra AK, Stanberry LR, Sawada R, Scholz WW, Sircar J. Peterson JW, et al. Among authors: noffsinger dm. Infect Immun. 2007 Jul;75(7):3414-24. doi: 10.1128/IAI.00352-07. Epub 2007 Apr 23. Infect Immun. 2007. PMID: 17452469 Free PMC article.