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Dorsal pancreas agenesis in retinoic acid-deficient Raldh2 mutant mice.
Martín M, Gallego-Llamas J, Ribes V, Kedinger M, Niederreither K, Chambon P, Dollé P, Gradwohl G. Martín M, et al. Among authors: chambon p. Dev Biol. 2005 Aug 15;284(2):399-411. doi: 10.1016/j.ydbio.2005.05.035. Dev Biol. 2005. PMID: 16026781 Free article.
The regional pattern of retinoic acid synthesis by RALDH2 is essential for the development of posterior pharyngeal arches and the enteric nervous system.
Niederreither K, Vermot J, Le Roux I, Schuhbaur B, Chambon P, Dollé P. Niederreither K, et al. Among authors: chambon p. Development. 2003 Jun;130(11):2525-34. doi: 10.1242/dev.00463. Development. 2003. PMID: 12702665
Transient maternal RA supplementation from E7.5 to (at least) E8.5 rescues most of these defects, but the supplemented Raldh2(-/-) mutants die prenatally, from a lack of septation of the heart outflow tract (Niederreither, K., Vermot, J., Messaddeq, N., Schuhbaur, B., Chambon …
Transient maternal RA supplementation from E7.5 to (at least) E8.5 rescues most of these defects, but the supplemented Raldh2(-/-) mutants d …
1,063 results