Saeed M - Search Results

1

The greater reactivity of estradiol-3,4-quinone vs estradiol-2,3-quinone with DNA in the formation of depurinating adducts: implications for tumor-initiating activity.

Zahid M, Kohli E, Saeed M, Rogan E, Cavalieri E. Zahid M, et al. Among authors: saeed m. Chem Res Toxicol. 2006 Jan;19(1):164-72. doi: 10.1021/tx050229y. Chem Res Toxicol. 2006. PMID: 16411670

2

Catechol ortho-quinones: the electrophilic compounds that form depurinating DNA adducts and could initiate cancer and other diseases.

Cavalieri EL, Li KM, Balu N, Saeed M, Devanesan P, Higginbotham S, Zhao J, Gross ML, Rogan EG. Cavalieri EL, et al. Among authors: saeed m. Carcinogenesis. 2002 Jun;23(6):1071-7. doi: 10.1093/carcin/23.6.1071. Carcinogenesis. 2002. PMID: 12082031

3

Slow loss of deoxyribose from the N7deoxyguanosine adducts of estradiol-3,4-quinone and hexestrol-3',4'-quinone. Implications for mutagenic activity.

Saeed M, Zahid M, Gunselman SJ, Rogan E, Cavalieri E. Saeed M, et al. Steroids. 2005 Jan;70(1):29-35. doi: 10.1016/j.steroids.2004.09.011. Epub 2004 Nov 23. Steroids. 2005. PMID: 15610894

4

Formation of the depurinating N3adenine and N7guanine adducts by reaction of DNA with hexestrol-3',4'-quinone or enzyme-activated 3'-hydroxyhexestrol. Implications for a unifying mechanism of tumor initiation by natural and synthetic estrogens.

Saeed M, Gunselman SJ, Higginbotham S, Rogan E, Cavalieri E. Saeed M, et al. Steroids. 2005 Jan;70(1):37-45. doi: 10.1016/j.steroids.2004.09.012. Epub 2004 Nov 24. Steroids. 2005. PMID: 15610895

5

Formation of depurinating N3adenine and N7guanine adducts after reaction of 1,2-naphthoquinone or enzyme-activated 1,2-dihydroxynaphthalene with DNA. Implications for the mechanism of tumor initiation by naphthalene.

Saeed M, Higginbotham S, Rogan E, Cavalieri E. Saeed M, et al. Chem Biol Interact. 2007 Feb 20;165(3):175-88. doi: 10.1016/j.cbi.2006.12.007. Epub 2006 Dec 16. Chem Biol Interact. 2007. PMID: 17224140

6

Formation of depurinating N3Adenine and N7Guanine adducts by MCF-10F cells cultured in the presence of 4-hydroxyestradiol.

Saeed M, Rogan E, Fernandez SV, Sheriff F, Russo J, Cavalieri E. Saeed M, et al. Int J Cancer. 2007 Apr 15;120(8):1821-4. doi: 10.1002/ijc.22399. Int J Cancer. 2007. PMID: 17230531

7

Estrogen metabolism and formation of estrogen-DNA adducts in estradiol-treated MCF-10F cells. The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin induction and catechol-O-methyltransferase inhibition.

Lu F, Zahid M, Saeed M, Cavalieri EL, Rogan EG. Lu F, et al. Among authors: saeed m. J Steroid Biochem Mol Biol. 2007 Jun-Jul;105(1-5):150-8. doi: 10.1016/j.jsbmb.2006.12.102. Epub 2007 May 16. J Steroid Biochem Mol Biol. 2007. PMID: 17582757 Free PMC article.

8

Inhibition of catechol-O-methyltransferase increases estrogen-DNA adduct formation.

Zahid M, Saeed M, Lu F, Gaikwad N, Rogan E, Cavalieri E. Zahid M, et al. Among authors: saeed m. Free Radic Biol Med. 2007 Dec 1;43(11):1534-40. doi: 10.1016/j.freeradbiomed.2007.08.005. Epub 2007 Aug 19. Free Radic Biol Med. 2007. PMID: 17964424 Free PMC article.

9

Prevention of estrogen-DNA adduct formation in MCF-10F cells by resveratrol.

Zahid M, Gaikwad NW, Ali MF, Lu F, Saeed M, Yang L, Rogan EG, Cavalieri EL. Zahid M, et al. Among authors: saeed m. Free Radic Biol Med. 2008 Jul 15;45(2):136-45. doi: 10.1016/j.freeradbiomed.2008.03.017. Epub 2008 Apr 8. Free Radic Biol Med. 2008. PMID: 18423413 Free PMC article.

10

Mechanism of metabolic activation and DNA adduct formation by the human carcinogen diethylstilbestrol: the defining link to natural estrogens.

Saeed M, Rogan E, Cavalieri E. Saeed M, et al. Int J Cancer. 2009 Mar 15;124(6):1276-84. doi: 10.1002/ijc.24113. Int J Cancer. 2009. PMID: 19089919 Free PMC article.

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