Ramírez de Molina A - Search Results

1

Noninvasive magnetic resonance spectroscopic pharmacodynamic markers of the choline kinase inhibitor MN58b in human carcinoma models.

Al-Saffar NM, Troy H, Ramírez de Molina A, Jackson LE, Madhu B, Griffiths JR, Leach MO, Workman P, Lacal JC, Judson IR, Chung YL. Al-Saffar NM, et al. Among authors: ramirez de molina a. Cancer Res. 2006 Jan 1;66(1):427-34. doi: 10.1158/0008-5472.CAN-05-1338. Cancer Res. 2006. PMID: 16397258

2

Targeting new anticancer drugs within signalling pathways regulated by the Ras GTPase superfamily (Review).

Ramírez De Molina A, Rodríguez-González A, Lacal JC. Ramírez De Molina A, et al. Int J Oncol. 2001 Jul;19(1):5-17. Int J Oncol. 2001. PMID: 11408916 Review.

3

Inhibition of ChoK is an efficient antitumor strategy for Harvey-, Kirsten-, and N-ras-transformed cells.

Ramírez de Molina A, Rodríguez-González A, Penalva V, Lucas L, Lacal JC. Ramírez de Molina A, et al. Biochem Biophys Res Commun. 2001 Jul 27;285(4):873-9. doi: 10.1006/bbrc.2001.5250. Biochem Biophys Res Commun. 2001. PMID: 11467831

4

Regulation of choline kinase activity by Ras proteins involves Ral-GDS and PI3K.

Ramírez de Molina A, Penalva V, Lucas L, Lacal JC. Ramírez de Molina A, et al. Oncogene. 2002 Jan 31;21(6):937-46. doi: 10.1038/sj.onc.1205144. Oncogene. 2002. PMID: 11840339

5

Increased choline kinase activity in human breast carcinomas: clinical evidence for a potential novel antitumor strategy.

Ramírez de Molina A, Gutiérrez R, Ramos MA, Silva JM, Silva J, Bonilla F, Sánchez JJ, Lacal JC. Ramírez de Molina A, et al. Oncogene. 2002 Jun 20;21(27):4317-22. doi: 10.1038/sj.onc.1205556. Oncogene. 2002. PMID: 12082619

6

Overexpression of choline kinase is a frequent feature in human tumor-derived cell lines and in lung, prostate, and colorectal human cancers.

Ramírez de Molina A, Rodríguez-González A, Gutiérrez R, Martínez-Piñeiro L, Sánchez J, Bonilla F, Rosell R, Lacal J. Ramírez de Molina A, et al. Biochem Biophys Res Commun. 2002 Aug 23;296(3):580-3. doi: 10.1016/s0006-291x(02)00920-8. Biochem Biophys Res Commun. 2002. PMID: 12176020

7

Phospholipase D and choline kinase: their role in cancer development and their potential as drug targets.

Rodríguez-González A, Ramírez de Molina A, Benítez-Rajal J, Lacal JC. Rodríguez-González A, et al. Among authors: ramirez de molina a. Prog Cell Cycle Res. 2003;5:191-201. Prog Cell Cycle Res. 2003. PMID: 14593713 Review.

8

Inhibition of choline kinase as a specific cytotoxic strategy in oncogene-transformed cells.

Rodríguez-González A, Ramírez de Molina A, Fernández F, Ramos MA, del Carmen Núñez M, Campos J, Lacal JC. Rodríguez-González A, et al. Among authors: ramirez de molina a. Oncogene. 2003 Dec 4;22(55):8803-12. doi: 10.1038/sj.onc.1207062. Oncogene. 2003. PMID: 14654777

9

From Ras signalling to ChoK inhibitors: a further advance in anticancer drug design.

Ramírez de Molina A, Rodríguez-González A, Lacal JC. Ramírez de Molina A, et al. Cancer Lett. 2004 Apr 8;206(2):137-48. doi: 10.1016/j.canlet.2003.08.031. Cancer Lett. 2004. PMID: 15013519 Review.

10

Choline kinase activation is a critical requirement for the proliferation of primary human mammary epithelial cells and breast tumor progression.

Ramírez de Molina A, Báñez-Coronel M, Gutiérrez R, Rodríguez-González A, Olmeda D, Megías D, Lacal JC. Ramírez de Molina A, et al. Cancer Res. 2004 Sep 15;64(18):6732-9. doi: 10.1158/0008-5472.CAN-04-0489. Cancer Res. 2004. PMID: 15374991

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