Horwitz SB - Search Results

1

Potentiation of taxol efficacy and by discodermolide in ovarian carcinoma xenograft-bearing mice.

Huang GS, Lopez-Barcons L, Freeze BS, Smith AB 3rd, Goldberg GL, Horwitz SB, McDaid HM. Huang GS, et al. Among authors: horwitz sb. Clin Cancer Res. 2006 Jan 1;12(1):298-304. doi: 10.1158/1078-0432.CCR-05-0229. Clin Cancer Res. 2006. PMID: 16397055 Free PMC article.

2

Activation of the steroid and xenobiotic receptor (human pregnane X receptor) by nontaxane microtubule-stabilizing agents.

Mani S, Huang H, Sundarababu S, Liu W, Kalpana G, Smith AB, Horwitz SB. Mani S, et al. Among authors: horwitz sb. Clin Cancer Res. 2005 Sep 1;11(17):6359-69. doi: 10.1158/1078-0432.CCR-05-0252. Clin Cancer Res. 2005. PMID: 16144941

3

The effect of ketoconazole on the pharmacokinetics and pharmacodynamics of ixabepilone: a first in class epothilone B analogue in late-phase clinical development.

Goel S, Cohen M, Cömezoglu SN, Perrin L, André F, Jayabalan D, Iacono L, Comprelli A, Ly VT, Zhang D, Xu C, Humphreys WG, McDaid H, Goldberg G, Horwitz SB, Mani S. Goel S, et al. Among authors: horwitz sb. Clin Cancer Res. 2008 May 1;14(9):2701-9. doi: 10.1158/1078-0432.CCR-07-4151. Clin Cancer Res. 2008. PMID: 18451235 Clinical Trial.

4

The microtubule stabilizing agent discodermolide is a potent inducer of accelerated cell senescence.

Klein LE, Freeze BS, Smith AB 3rd, Horwitz SB. Klein LE, et al. Among authors: horwitz sb. Cell Cycle. 2005 Mar;4(3):501-7. doi: 10.4161/cc.4.3.1550. Epub 2005 Mar 18. Cell Cycle. 2005. PMID: 15711127

5

Enhancement of the therapeutic efficacy of taxol by the mitogen-activated protein kinase kinase inhibitor CI-1040 in nude mice bearing human heterotransplants.

McDaid HM, Lopez-Barcons L, Grossman A, Lia M, Keller S, Pérez-Soler R, Horwitz SB. McDaid HM, et al. Among authors: horwitz sb. Cancer Res. 2005 Apr 1;65(7):2854-60. doi: 10.1158/0008-5472.CAN-04-4391. Cancer Res. 2005. PMID: 15805287

6

Targeting protein translation in human non small cell lung cancer via combined MEK and mammalian target of rapamycin suppression.

Legrier ME, Yang CP, Yan HG, Lopez-Barcons L, Keller SM, Pérez-Soler R, Horwitz SB, McDaid HM. Legrier ME, et al. Among authors: horwitz sb. Cancer Res. 2007 Dec 1;67(23):11300-8. doi: 10.1158/0008-5472.CAN-07-0702. Cancer Res. 2007. PMID: 18056456

7

Insulin-like growth factor 2 expression modulates Taxol resistance and is a candidate biomarker for reduced disease-free survival in ovarian cancer.

Huang GS, Brouwer-Visser J, Ramirez MJ, Kim CH, Hebert TM, Lin J, Arias-Pulido H, Qualls CR, Prossnitz ER, Goldberg GL, Smith HO, Horwitz SB. Huang GS, et al. Among authors: horwitz sb. Clin Cancer Res. 2010 Jun 1;16(11):2999-3010. doi: 10.1158/1078-0432.CCR-09-3233. Epub 2010 Apr 19. Clin Cancer Res. 2010. PMID: 20404007 Free PMC article.

8

Resistance to discodermolide, a microtubule-stabilizing agent and senescence inducer, is 4E-BP1-dependent.

Chao SK, Lin J, Brouwer-Visser J, Smith AB 3rd, Horwitz SB, McDaid HM. Chao SK, et al. Among authors: horwitz sb. Proc Natl Acad Sci U S A. 2011 Jan 4;108(1):391-6. doi: 10.1073/pnas.1016962108. Epub 2010 Dec 20. Proc Natl Acad Sci U S A. 2011. PMID: 21173253 Free PMC article.

9

Structural Refinement of the Tubulin Ligand (+)-Discodermolide to Attenuate Chemotherapy-Mediated Senescence.

Guo B, Rodriguez-Gabin A, Prota AE, Mühlethaler T, Zhang N, Ye K, Steinmetz MO, Horwitz SB, Smith AB 3rd, McDaid HM. Guo B, et al. Among authors: horwitz sb. Mol Pharmacol. 2020 Aug;98(2):156-167. doi: 10.1124/mol.119.117457. Epub 2020 Jun 26. Mol Pharmacol. 2020. PMID: 32591477 Free PMC article.

10

Taxol in ovarian cancer.

Runowicz CD, Wiernik PH, Einzig AI, Goldberg GL, Horwitz SB. Runowicz CD, et al. Among authors: horwitz sb. Cancer. 1993 Feb 15;71(4 Suppl):1591-6. doi: 10.1002/cncr.2820710442. Cancer. 1993. PMID: 8094322 Review.

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