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A feedback amplifier circuit with Notch and E2A orchestrates T-cell fate and suppresses the innate lymphoid cell lineages during thymic ontogeny.
Miyazaki K, Horie K, Watanabe H, Hidaka R, Hayashi R, Hayatsu N, Fujiwara K, Kuwata R, Uehata T, Ochi Y, Takenaka M, Kawaguchi RK, Ikuta K, Takeuchi O, Ogawa S, Hozumi K, Holländer GA, Kondoh G, Akiyama T, Miyazaki M. Miyazaki K, et al. Among authors: hayashi r. Genes Dev. 2025 Feb 4. doi: 10.1101/gad.352111.124. Online ahead of print. Genes Dev. 2025. PMID: 39904558
First-line biologics as a treatment for ulcerative colitis: a multicenter randomized control study.
Naganuma M, Shiga H, Shimoda M, Matsuura M, Takenaka K, Fujii T, Yamamoto S, Matsubayashi M, Kobayashi T, Aoyama N, Saito D, Yokoyama K, Moriya K, Tsuchiya K, Shibui S, Kawamoto A, Shimizu H, Okamoto R, Sakamoto K, Yaguchi K, Kunisaki R, Akiyama S, Hayashi R, Hasui K, Kanmura S, Bamba S, Mishima Y, Kakimoto K, Sugimoto S, Nakazawa A, Abe T, Ogata H, Hisamatsu T; Collaborators of the Study. Naganuma M, et al. Among authors: hayashi r. J Gastroenterol. 2025 Jan 30. doi: 10.1007/s00535-025-02216-0. Online ahead of print. J Gastroenterol. 2025. PMID: 39883201
Role of transforming growth factor-β1 in regulating adipocyte progenitors.
Phuong NQ, Bilal M, Nawaz A, Anh LD, Memoona, Aslam MR, Khalid S, Kado T, Watanabe Y, Nishimura A, Igarashi Y, Okabe K, Hirabayashi K, Yamamoto S, Nakagawa T, Mori H, Usui I, Fujisaka S, Hayashi R, Tobe K. Phuong NQ, et al. Among authors: hayashi r. Sci Rep. 2025 Jan 17;15(1):941. doi: 10.1038/s41598-024-81917-7. Sci Rep. 2025. PMID: 39824986 Free PMC article.
Blood DNA virome associates with autoimmune diseases and COVID-19.
Sasa N, Kojima S, Koide R, Hasegawa T, Namkoong H, Hirota T, Watanabe R, Nakamura Y, Oguro-Igashira E, Ogawa K, Yata T, Sonehara K, Yamamoto K, Kishikawa T, Sakaue S, Edahiro R, Shirai Y, Maeda Y, Nii T, Chubachi S, Tanaka H, Yabukami H, Suzuki A, Nakajima K, Arase N, Okamoto T, Nishikawa R, Namba S, Naito T, Miyagawa I, Tanaka H, Ueno M, Ishitsuka Y, Furuta J, Kunimoto K, Kajihara I, Fukushima S, Miyachi H, Matsue H, Kamata M, Momose M, Bito T, Nagai H, Ikeda T, Horikawa T, Adachi A, Matsubara T, Ikumi K, Nishida E, Nakagawa I, Yagita-Sakamaki M, Yoshimura M, Ohshima S, Kinoshita M, Ito S, Arai T, Hirose M, Tanino Y, Nikaido T, Ichiwata T, Ohkouchi S, Hirano T, Takada T, Tazawa R, Morimoto K, Takaki M, Konno S, Suzuki M, Tomii K, Nakagawa A, Handa T, Tanizawa K, Ishii H, Ishida M, Kato T, Takeda N, Yokomura K, Matsui T, Uchida A, Inoue H, Imaizumi K, Goto Y, Kida H, Fujisawa T, Suda T, Yamada T, Satake Y, Ibata H, Saigusa M, Shirai T, Hizawa N, Nakata K; Japan COVID-19 Task Force; Imafuku S, Tada Y, Asano Y, Sato S, Nishigori C, Jinnin M, Ihn H, Asahina A, Saeki H, Kawamura T, Shimada S, Katayama I, Poisner HM, Mack TM, Bick AG, Higasa K, Okuno T, Mochizuki H, Ishii M, Koike R, K… See abstract for full author list ➔ Sasa N, et al. Nat Genet. 2025 Jan;57(1):65-79. doi: 10.1038/s41588-024-02022-z. Epub 2025 Jan 3. Nat Genet. 2025. PMID: 39753770 Free PMC article.
Inadequate Efficacy of Biologics for Treating Proximal Ileal Lesions in Crohn's Disease; A Prospective Multicenter Study.
Takenaka K, Hisamatsu T, Kobayashi T, Yamamoto H, Ohmiya N, Hayashi R, Matsuoka K, Saruta M, Andoh A, Fukata N, Watanabe K, Imaeda H, Hirai F, Matsumoto T, Hirakawa A, Yano T, Matsuura M, Okamoto R, Ohtsuka K, Watanabe M. Takenaka K, et al. Among authors: hayashi r. Clin Gastroenterol Hepatol. 2024 Dec 16:S1542-3565(24)01084-X. doi: 10.1016/j.cgh.2024.10.030. Online ahead of print. Clin Gastroenterol Hepatol. 2024. PMID: 39694212
1,601 results