Whitman S - Search Results

1

Spectroscopic and biochemical characterization of heme binding to yeast Dap1p and mouse PGRMC1p.

Ghosh K, Thompson AM, Goldbeck RA, Shi X, Whitman S, Oh E, Zhiwu Z, Vulpe C, Holman TR. Ghosh K, et al. Among authors: whitman s. Biochemistry. 2005 Dec 20;44(50):16729-36. doi: 10.1021/bi0511585. Biochemistry. 2005. PMID: 16342963 Free PMC article.

2

Tryptophan 500 and arginine 707 define product and substrate active site binding in soybean lipoxygenase-1.

Ruddat VC, Mogul R, Chorny I, Chen C, Perrin N, Whitman S, Kenyon V, Jacobson MP, Bernasconi CF, Holman TR. Ruddat VC, et al. Among authors: whitman s. Biochemistry. 2004 Oct 19;43(41):13063-71. doi: 10.1021/bi0489098. Biochemistry. 2004. PMID: 15476400 Free article.

3

Stopped-flow kinetic investigations of the activation of soybean lipoxygenase-1 and the influence of inhibitors on the allosteric site.

Ruddat VC, Whitman S, Holman TR, Bernasconi CF. Ruddat VC, et al. Among authors: whitman s. Biochemistry. 2003 Apr 15;42(14):4172-8. doi: 10.1021/bi020698o. Biochemistry. 2003. PMID: 12680771 Free article.

4

An analysis of phakellin and oroidin structures stimulated by further study of an Agelas sponge.

Gautschi JT, Whitman S, Holman TR, Crews P. Gautschi JT, et al. Among authors: whitman s. J Nat Prod. 2004 Aug;67(8):1256-61. doi: 10.1021/np0340495. J Nat Prod. 2004. PMID: 15332838

5

Evidence for downregulation of calcium signaling proteins in advanced mouse adenocarcinoma.

Ruddat VC, Whitman S, Klein RD, Fischer SM, Holman TR. Ruddat VC, et al. Among authors: whitman s. Prostate. 2005 Jul 1;64(2):128-38. doi: 10.1002/pros.20207. Prostate. 2005. PMID: 15666362 Free article.

6

Structure-activity relationship studies of nordihydroguaiaretic acid inhibitors toward soybean, 12-human, and 15-human lipoxygenase.

Whitman S, Gezginci M, Timmermann BN, Holman TR. Whitman S, et al. J Med Chem. 2002 Jun 6;45(12):2659-61. doi: 10.1021/jm0201262. J Med Chem. 2002. PMID: 12036375 Free article.

7

Redox inactivation of human 15-lipoxygenase by marine-derived meroditerpenes and synthetic chromanes: archetypes for a unique class of selective and recyclable inhibitors.

Cichewicz RH, Kenyon VA, Whitman S, Morales NM, Arguello JF, Holman TR, Crews P. Cichewicz RH, et al. Among authors: whitman s. J Am Chem Soc. 2004 Nov 17;126(45):14910-20. doi: 10.1021/ja046082z. J Am Chem Soc. 2004. PMID: 15535718 Free article.

8

Exploring sponge-derived terpenoids for their potency and selectivity against 12-human, 15-human, and 15-soybean lipoxygenases.

Amagata T, Whitman S, Johnson TA, Stessman CC, Loo CP, Lobkovsky E, Clardy J, Crews P, Holman TR. Amagata T, et al. Among authors: whitman s. J Nat Prod. 2003 Feb;66(2):230-5. doi: 10.1021/np020462l. J Nat Prod. 2003. PMID: 12608855 Free article.

9

Probing the activity differences of simple and complex brominated aryl compounds against 15-soybean, 15-human, and 12-human lipoxygenase.

Segraves EN, Shah RR, Segraves NL, Johnson TA, Whitman S, Sui JK, Kenyon VA, Cichewicz RH, Crews P, Holman TR. Segraves EN, et al. Among authors: whitman s. J Med Chem. 2004 Jul 29;47(16):4060-5. doi: 10.1021/jm049872s. J Med Chem. 2004. PMID: 15267244 Free article.

10

Discovery of platelet-type 12-human lipoxygenase selective inhibitors by high-throughput screening of structurally diverse libraries.

Deschamps JD, Gautschi JT, Whitman S, Johnson TA, Gassner NC, Crews P, Holman TR. Deschamps JD, et al. Among authors: whitman s. Bioorg Med Chem. 2007 Nov 15;15(22):6900-8. doi: 10.1016/j.bmc.2007.08.015. Epub 2007 Aug 22. Bioorg Med Chem. 2007. PMID: 17826100 Free PMC article.

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